Simulation model for assessing quality of ultrasound strain estimation in abdominal aortic aneurysm.

The purpose of this study was to develop a simulation model for evaluating methods for ultrasound strain estimation in abdominal aortic aneurysms. Wall geometry was obtained from a real ultrasound image and wall motion was simulated applying realistic blood pressures to a nonlinear viscoelastic wall model. The ultrasound simulation included speckle, absorption and angle dependent reflection. Gaussian white noise was added to simulate various noise levels. Despite not fully replicating real ultrasound images, the model simulated realistic circumferential variations in intensity and realistic speckle patterns and has potential for initial evaluation of strain estimation methods.

[1]  Mark F Fillinger,et al.  Prediction of rupture risk in abdominal aortic aneurysm during observation: wall stress versus diameter. , 2003, Journal of vascular surgery.

[2]  M. Webster,et al.  Ex vivo biomechanical behavior of abdominal aortic aneurysm: Assessment using a new mathematical model , 1996, Annals of Biomedical Engineering.

[3]  Peter R Hoskins,et al.  The relationship between aortic wall distensibility and rupture of infrarenal abdominal aortic aneurysm. , 2003, Journal of vascular surgery.

[4]  Jonathan P Vande Geest,et al.  Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue. , 2006, Journal of vascular surgery.

[5]  Jacques Ohayon,et al.  Adapting the Lagrangian speckle model estimator for endovascular elastography: theory and validation with simulated radio-frequency data. , 2004, The Journal of the Acoustical Society of America.

[6]  D. Vorp,et al.  The effects of aneurysm on the biaxial mechanical behavior of human abdominal aorta. , 2006, Journal of biomechanics.

[7]  J. D'hooge,et al.  A fast convolution-based methodology to simulate 2-Dd/3-D cardiac ultrasound images , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  Reidar Brekken,et al.  Strain estimation in abdominal aortic aneurysms from 2-D ultrasound. , 2006, Ultrasound in medicine & biology.

[9]  T. Hergum,et al.  Fast ultrasound imaging simulation in K-space , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[10]  M. R. Roach,et al.  The composition and mechanical properties of abdominal aortic aneurysms. , 1994, Journal of vascular surgery.

[11]  M. Webster,et al.  Wall stress distribution on three-dimensionally reconstructed models of human abdominal aortic aneurysm. , 2000, Journal of vascular surgery.

[12]  Jonas Crosby,et al.  The effect of including myocardial anisotropy in simulated ultrasound images of the heart , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[13]  H. Torp,et al.  Ultrasound simulation of complex flow velocity fields based on computational fluid dynamics , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  T Länne,et al.  Abdominal aortic aneurysm wall mechanics and their relation to risk of rupture. , 1999, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[15]  Elena S. Di Martino,et al.  Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm. , 2001, Medical engineering & physics.

[16]  R. Cobbold.  Foundations of Biomedical Ultrasound , 2006 .

[17]  B J B M Wolters,et al.  A patient-specific computational model of fluid-structure interaction in abdominal aortic aneurysms. , 2005, Medical engineering & physics.

[18]  M. Thubrikar,et al.  Mechanical properties of abdominal aortic aneurysm wall , 2001, Journal of medical engineering & technology.

[19]  Bui Tuong Phong.  Illumination for computer generated pictures , 1975, Commun. ACM.

[20]  E H WOOD,et al.  Formation of peripheral pulse contour in man. , 1956, Journal of applied physiology.

[21]  J. D'hooge,et al.  A virtual environment for the evaluation, validation and optimization of strain and strain rate imaging , 2003, IEEE Symposium on Ultrasonics, 2003.

[22]  D. C. Brewster,et al.  Guidelines for the treatment of abdominal aortic aneurysms. Report of a subcommittee of the Joint Council of the American Association for Vascular Surgery and Society for Vascular Surgery. , 2003, Journal of vascular surgery.