Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance.

[1]  M. Matsui,et al.  In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. , 2003, Molecular biology of the cell.

[2]  Masaaki Komatsu,et al.  Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice , 2005, The Journal of cell biology.

[3]  L. Rossetti,et al.  Hypothalamic sensing of fatty acids , 2005, Nature Neuroscience.

[4]  Masaaki Komatsu,et al.  Loss of autophagy in the central nervous system causes neurodegeneration in mice , 2006, Nature.

[5]  G. Barsh,et al.  Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake , 2006, Nature Medicine.

[6]  Hideyuki Okano,et al.  Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice , 2006, Nature.

[7]  F. Cordelières,et al.  A guided tour into subcellular colocalization analysis in light microscopy , 2006, Journal of microscopy.

[8]  George Thomas,et al.  Hypothalamic mTOR Signaling Regulates Food Intake , 2006, Science.

[9]  R. Taulli,et al.  Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas. , 2006, Blood.

[10]  Jianping Ye,et al.  Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism. , 2007, American journal of physiology. Endocrinology and metabolism.

[11]  A. Cuervo Autophagy and aging: keeping that old broom working. , 2008, Trends in genetics : TIG.

[12]  S. Pattingre,et al.  Regulation of macroautophagy by mTOR and Beclin 1 complexes. , 2008, Biochimie.

[13]  J. Olefsky,et al.  Inflammation and insulin resistance , 2008, FEBS letters.

[14]  Tamas L. Horvath,et al.  UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals , 2008, Nature.

[15]  Ralph A. Nixon,et al.  Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease , 2008, The Journal of Neuroscience.

[16]  A. Garfield,et al.  Role of central melanocortin pathways in energy homeostasis , 2009, Trends in Endocrinology & Metabolism.

[17]  A. Lombardi,et al.  From chronic overnutrition to insulin resistance: the role of fat-storing capacity and inflammation. , 2009, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[18]  D. Klionsky,et al.  Regulation mechanisms and signaling pathways of autophagy. , 2009, Annual review of genetics.

[19]  M. Czaja,et al.  Autophagy regulates lipid metabolism , 2009, Nature.

[20]  L. Rui,et al.  Recent advances in understanding leptin signaling and leptin resistance. , 2009, American journal of physiology. Endocrinology and metabolism.

[21]  M. Czaja,et al.  Autophagy regulates adipose mass and differentiation in mice. , 2009, The Journal of clinical investigation.

[22]  Mohammad A Ghatei,et al.  Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance , 2009, International Journal of Obesity.

[23]  J. Brüning,et al.  CNS leptin and insulin action in the control of energy homeostasis , 2010, Annals of the New York Academy of Sciences.

[24]  A. Cuervo,et al.  Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation , 2010, The Journal of Immunology.

[25]  K. Mountjoy Functions for pro-opiomelanocortin-derived peptides in obesity and diabetes. , 2010, The Biochemical journal.

[26]  D. Sulzer,et al.  CARGO RECOGNITION FAILURE IS RESPONSIBLE FOR INEFFICIENT AUTOPHAGY IN HUNTINGTON’S DISEASE , 2010, Nature Neuroscience.

[27]  A. Sainsbury,et al.  Role of the arcuate nucleus of the hypothalamus in regulation of body weight during energy deficit , 2010, Molecular and Cellular Endocrinology.

[28]  B. Viollet,et al.  Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy , 2011, Science.