Line-reconstruction from Compton cameras: data sets and a camera design

Reconstructing the integral of a distribution of radioactivity along a line from Compton camera data could be used to produce a parallel projection, or to perform tomosynthesis, or to reconstruct the whole three-dimensional distribution itself. Analytic methods for reconstructing an integral of radioactivity along a line are presented here. The sets of data that allow an integral along a line and a parallel projection of the distribution to be reconstructed are determined here by interpreting these methods from a geometric viewpoint. These methods and the sets of data depend upon which of the two models is assumed for the data. Both of these models have been previously proposed by other researchers. In addition, a new camera design is proposed here that makes it possible to measure all these sets of data. In this design, a first detector element has to be seen from the second detector in only a "semicircle of direction." Also, two techniques for increasing the sensitivity of the new camera design are proposed here. Computer simulations are performed to illustrate these reconstruction methods.

[1]  B. Phlips,et al.  An advanced Compton telescope based on thick, position-sensitive solid-state detectors , 2004 .

[2]  P. Bleuet,et al.  An adapted fan volume sampling scheme for 3-D algebraic reconstruction in linear tomosynthesis , 2001 .

[3]  A. Cormack Representation of a Function by Its Line Integrals, with Some Radiological Applications , 1963 .

[4]  R. Bracewell The Fourier Transform and Its Applications , 1966 .

[5]  J. M. Nightingale,et al.  A proposed γ camera , 1974, Nature.

[6]  S. E. Boggs,et al.  Event reconstruction in high resolution Compton telescopes , 2000 .

[7]  Zhong He,et al.  4/spl pi/ Compton imaging using a 3-D position-sensitive CdZnTe detector via weighted list-mode maximum likelihood , 2003, 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515).

[8]  H. Haba,et al.  Multiple molecular simultaneous imaging in a live mouse using semiconductor Compton camera , 2008 .

[9]  G. W. Phillips Gamma-ray imaging with Compton cameras , 1995 .

[10]  Chan Hyeong Kim,et al.  Two approaches to implementing projector–backprojector pairs for 3D reconstruction from Compton scattered data , 2007 .

[11]  Manbir Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part I: Theoretical considerations and design criteria , 1983 .

[12]  C. Lanczos Applied Analysis , 1961 .

[13]  Mark L. McConnell,et al.  Using LaX scintillator in a new low-background Compton telescope , 2007, SPIE Optical Engineering + Applications.

[14]  J A Rowlands,et al.  Megavoltage cone beam digital tomosynthesis (MV-CBDT) for image-guided radiotherapy: a clinical investigational system , 2008, Physics in medicine and biology.

[15]  Steven Boggs,et al.  Performance of the Nuclear Compton Telescope , 2005 .

[16]  P. Antich,et al.  Compact Compton camera design: parameters and imaging algorithms , 2000, 2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149).

[17]  Manbir Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements , 1983 .

[18]  James D. Kurfess,et al.  Position sensitive germanium detectors for the Advanced Compton Telescope , 2000 .

[19]  D. Hanna,et al.  Simulations of a Scintillator Compton Gamma Imager for Safety and Security , 2008, IEEE Transactions on Nuclear Science.

[20]  Tao Wu,et al.  A comparison of reconstruction algorithms for breast tomosynthesis. , 2004, Medical physics.

[21]  J Pouliot,et al.  Characteristics of megavoltage cone-beam digital tomosynthesis. , 2008, Medical physics.

[22]  G. Shilov,et al.  PARTICULAR TYPES OF GENERALIZED FUNCTIONS , 1964 .

[23]  Bruce D. Smith Image Reconstruction from Cone-Beam Projections: Necessary and Sufficient Conditions and Reconstruction Methods , 1985, IEEE Transactions on Medical Imaging.

[24]  D. G. Grant Tomosynthesis: a three-dimensional radiographic imaging technique. , 1972, IEEE transactions on bio-medical engineering.

[25]  B. G. Ziedses des Plantes,et al.  Eine Neue Methode Zur Differenzierung in der Rontgenographie (Planigraphies) , 1932 .

[26]  Richard L. Webber,et al.  Restoration of Digital Multiplane Tomosynthesis by a Constrained Iteration Method , 1984, IEEE Transactions on Medical Imaging.

[27]  Er-Wei Bai,et al.  An in vitro evaluation of cone-beam breast CT methods. , 2008, Journal of X-ray science and technology.

[28]  T. Tomitani,et al.  Image reconstruction from limited angle Compton camera data , 2002, Physics in medicine and biology.

[29]  L. Parra,et al.  Reconstruction of cone-beam projections from Compton scattered data , 1999, 1999 IEEE Nuclear Science Symposium. Conference Record. 1999 Nuclear Science Symposium and Medical Imaging Conference (Cat. No.99CH37019).

[30]  Philip J. Bones,et al.  Towards direct reconstruction from a gamma camera based on Compton scattering , 1994, IEEE Trans. Medical Imaging.

[31]  Jonathan Raby Earnhart A Compton camera for spectroscopic imaging from 100 keV to 1 MeV , 1998 .

[32]  A. H. Compton A Quantum Theory of the Scattering of X-rays by Light Elements , 1923 .

[33]  James T Dobbins,et al.  Digital x-ray tomosynthesis: current state of the art and clinical potential. , 2003, Physics in medicine and biology.

[34]  F. Natterer The Mathematics of Computerized Tomography , 1986 .

[35]  James D. Kurfess,et al.  Compton imager for detection of special nuclear material , 2007 .

[36]  Gardner,et al.  Simulation of Compton camera imaging with a specific purpose Monte Carlo code , 2000, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[37]  T. Tomitani,et al.  An analytical image reconstruction algorithm to compensate for scattering angle broadening in Compton cameras. , 2003, Physics in medicine and biology.

[38]  Bruce Smith,et al.  Reconstruction methods and completeness conditions for two Compton data models. , 2005, Journal of the Optical Society of America. A, Optics, image science, and vision.

[39]  G T Gullberg,et al.  Application of spherical harmonics to image reconstruction for the Compton camera. , 1998, Physics in medicine and biology.

[40]  Berthold K. P. Horn Density reconstruction using arbitrary ray-sampling schemes , 1978 .

[41]  R L Webber,et al.  An optimal synthetic aperture for circular tomosynthesis. , 1989, Medical physics.

[42]  K. Lange,et al.  EM reconstruction algorithms for emission and transmission tomography. , 1984, Journal of computer assisted tomography.

[43]  M. McConnell,et al.  Instrument description and performance of the Imaging Gamma-Ray Telescope COMPTEL aboard the Compton Gamma-Ray Observatory , 1993 .

[44]  Design of a small laboratory Compton camera for the imaging of positron emitters , 1998, 1998 IEEE Nuclear Science Symposium Conference Record. 1998 IEEE Nuclear Science Symposium and Medical Imaging Conference (Cat. No.98CH36255).

[45]  L. Shepp,et al.  Maximum Likelihood Reconstruction for Emission Tomography , 1983, IEEE Transactions on Medical Imaging.

[46]  A. H. Walenta,et al.  Impact of the detector parameters on a Compton camera , 2002 .