Is Alzheimer's a disease of the white matter?
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Lin Zhuang | P. Sachdev | W. Wen | N. Braidy | Zhuang Lin
[1] R. Escourolle,et al. Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy , 1985, Annals of neurology.
[2] A. Brun,et al. A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study , 1986, Annals of neurology.
[3] S. M. de la Monte. Quantitation of cerebral atrophy in preclinical and end‐stage alzheimer's disease , 1989, Annals of neurology.
[4] S. M. de la Monte,et al. Quantitation of cerebral atrophy in preclinical and end‐stage alzheimer's disease , 1989, Annals of neurology.
[5] A Brun,et al. White matter changes in dementia of Alzheimer's type: the difference in vulnerability between cell compartments , 1990, Histopathology.
[6] W. Yuh,et al. Leukoencephalopathy in cerebral amyloid angiopathy: MR imaging in four cases. , 1990, AJNR. American journal of neuroradiology.
[7] P. Scheltens,et al. White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer's disease. Evidence for heterogeneity. , 1992, Brain : a journal of neurology.
[8] Albert Hofman,et al. Cognitive Correlates of Ventricular Enlargement and Cerebral White Matter Lesions on Magnetic Resonance Imaging: The Rotterdam Study , 1994, Stroke.
[9] A. Hofman,et al. Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study , 1994, Neurology.
[10] Khadija Iqbal,et al. Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[11] H. Braak,et al. Evolution of the neuropathology of Alzheimer's disease , 1996, Acta neurologica Scandinavica. Supplementum.
[12] P. Basser,et al. Diffusion tensor MR imaging of the human brain. , 1996, Radiology.
[13] Joseph H. Su,et al. Amyloid deposition in cerebrovascular angiopathy. , 1997, Annals of the New York Academy of Sciences.
[14] E. Mandelkow,et al. Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease , 1998, The Journal of cell biology.
[15] Yu-Min Kuo,et al. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease. , 1998, The American journal of pathology.
[16] R O Weller,et al. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease. , 1998, The American journal of pathology.
[17] Elisabet Englund,et al. Neuropathology of White Matter Changes in Alzheimer’s Disease and Vascular Dementia , 1998, Dementia and Geriatric Cognitive Disorders.
[18] R. Weller,et al. Cerebral Amyloid Angiopathy: Accumulation of Aβ in Interstitial Fluid Drainage Pathways in Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.
[19] R. Weller,et al. Cerebral amyloid angiopathy: accumulation of A beta in interstitial fluid drainage pathways in Alzheimer's disease. , 2000, Annals of the New York Academy of Sciences.
[20] R. Nitsch,et al. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.
[21] M. Goldberg,et al. Amyloid-β Peptides Are Cytotoxic to Oligodendrocytes , 2001, The Journal of Neuroscience.
[22] D. Le Bihan,et al. Diffusion tensor imaging: Concepts and applications , 2001, Journal of magnetic resonance imaging : JMRI.
[23] Yu-Min Kuo,et al. Increased Aβ Peptides and Reduced Cholesterol and Myelin Proteins Characterize White Matter Degeneration in Alzheimer's Disease† , 2002 .
[24] E. Englund,et al. Cerebral Amyloid Angiopathy, White Matter Lesions and Alzheimer Encephalopathy – A Histopathological Assessment , 2002, Dementia and Geriatric Cognitive Disorders.
[25] J. Hardy,et al. The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .
[26] E. Mandelkow,et al. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress , 2002, The Journal of cell biology.
[27] D. Selkoe. Alzheimer's Disease Is a Synaptic Failure , 2002, Science.
[28] N. Shahani,et al. Functions and malfunctions of the tau proteins , 2002, Cellular and Molecular Life Sciences CMLS.
[29] Douglas Walker,et al. Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease. , 2002, Biochemistry.
[30] V. Perry,et al. Axon pathology in neurological disease: a neglected therapeutic target , 2002, Trends in Neurosciences.
[31] A. Hofman,et al. Silent Brain Infarcts and White Matter Lesions Increase Stroke Risk in the General Population: The Rotterdam Scan Study , 2003, Stroke.
[32] M. Rossor. Contribution of cerebral amyloid angiopathy to Alzheimer ’ s disease , 2003 .
[33] E. Englund,et al. Glial levels determine severity of white matter disease in Alzheimer's disease: a neuropathological study of glial changes , 2003, Neuropathology and applied neurobiology.
[34] T. Beach,et al. Cortical and Leptomeningeal Cerebrovascular Amyloid and White Matter Pathology in Alzheimer’s Disease , 2003, Molecular medicine.
[35] A. Hofman,et al. Silent brain infarcts and the risk of dementia and cognitive decline. , 2003, The New England journal of medicine.
[36] F. LaFerla,et al. Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer’s disease , 2003, Neurobiology of Aging.
[37] G. Bartzokis. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer’s disease , 2004, Neurobiology of Aging.
[38] A. Hofman,et al. Cerebral white matter lesions and the risk of dementia. , 2004, Archives of neurology.
[39] P. Scheltens,et al. Measuring progression of cerebral white matter lesions on MRI , 2004, Neurology.
[40] G. Bartzokis,et al. Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical “disconnection” in aging and Alzheimer’s disease , 2004, Neurobiology of Aging.
[41] J. O'Brien,et al. Comparison of the pathology of cerebral white matter with post‐mortem magnetic resonance imaging (MRI) in the elderly brain , 2004, Neuropathology and applied neurobiology.
[42] Xianlin Han,et al. Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase–ceramide pathway , 2004, The Journal of Cell Biology.
[43] Sheng-Kwei Song,et al. Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition , 2004, Neurobiology of Disease.
[44] M. Rossor,et al. NEUROLOGICAL INFECTION AND INFLAMMATION , 2004, Journal of Neurology Neurosurgery & Psychiatry.
[45] R. Weller,et al. Cerebral amyloid angiopathy plays a direct role in the pathogenesis of Alzheimer’s disease Pro-CAA position statement , 2004, Neurobiology of Aging.
[46] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[47] Chi Li,et al. Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[48] G. Gong,et al. Evaluation of bilateral cingulum with tractography in patients with Alzheimer's disease , 2005, Neuroreport.
[49] Mahendra S Rao,et al. Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation , 2005, Nature Medicine.
[50] Alexandra Flemming,et al. Infectious disease: Unravelling SARS lethality , 2005, Nature Reviews Drug Discovery.
[51] D. Rowitch,et al. Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[52] S. Love,et al. Contributors to white matter damage in the frontal lobe in Alzheimer's disease , 2005, Neuropathology and applied neurobiology.
[53] E. Masliah,et al. Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease , 2005, Science.
[54] Min-Ying Su,et al. Regional Quantification of White Matter Hyperintensity in Normal Aging, Mild Cognitive Impairment, and Alzheimer’s Disease , 2006, Dementia and Geriatric Cognitive Disorders.
[55] J. O'Brien,et al. White Matter Lesions in an Unselected Cohort of the Elderly: Molecular Pathology Suggests Origin From Chronic Hypoperfusion Injury , 2006, Stroke.
[56] W. Klein,et al. Temporal Profile of Amyloid-β (Aβ) Oligomerization in an in Vivo Model of Alzheimer Disease , 2006, Journal of Biological Chemistry.
[57] Jacek Szczygielski,et al. Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease , 2006, Acta Neuropathologica.
[58] W. Klein,et al. Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. , 2006, The Journal of biological chemistry.
[59] Eric E. Smith,et al. White Matter Alterations in Cerebral Amyloid Angiopathy Measured by Diffusion Tensor Imaging , 2006, Stroke.
[60] N. Schuff,et al. Headache and cerebral venous air embolism , 2007, Neurology.
[61] V. Hachinski. The 2005 Thomas Willis Lecture: Stroke and Vascular Cognitive Impairment: A Transdisciplinary, Translational and Transactional Approach , 2007, Stroke.
[62] J. O'Brien,et al. Microglial activation in white matter lesions and nonlesional white matter of ageing brains , 2007, Neuropathology and applied neurobiology.
[63] J. O'Brien,et al. White matter lesions in an unselected cohort of the elderly: astrocytic, microglial and oligodendrocyte precursor cell responses , 2007, Neuropathology and applied neurobiology.
[64] Oliver Wirths,et al. Age-dependent axonal degeneration in an Alzheimer mouse model , 2007, Neurobiology of Aging.
[65] Hui Zheng,et al. In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease , 2007, NeuroImage.
[66] D. Selkoe,et al. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide , 2007, Nature Reviews Molecular Cell Biology.
[67] L. Mucke,et al. Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model , 2007, Science.
[68] Aidong Yuan,et al. Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice , 2008, The Journal of Neuroscience.
[69] S. Back,et al. Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury , 2008, Annals of neurology.
[70] J. Baron,et al. Relationships between Hippocampal Atrophy, White Matter Disruption, and Gray Matter Hypometabolism in Alzheimer's Disease , 2008, The Journal of Neuroscience.
[71] C. McCollum,et al. Paradoxical embolisation and cerebral white matter lesions in dementia. , 2008, The British journal of radiology.
[72] Eric E. Smith,et al. Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. , 2008, Archives of neurology.
[73] Bruce Fischl,et al. Regional white matter volume differences in nondemented aging and Alzheimer's disease , 2009, NeuroImage.
[74] J. O'Brien,et al. Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer’s disease, and dementia with Lewy bodies , 2010, Acta Neuropathologica.
[75] W. Bowers,et al. Triple‐transgenic Alzheimer's disease mice exhibit region‐specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology , 2009, Glia.
[76] Takahira Yamauchi,et al. Abnormalities of the uncinate fasciculus and posterior cingulate fasciculus in mild cognitive impairment and early Alzheimer's disease: A diffusion tensor tractography study , 2009, Brain Research.
[77] C. Yasuda,et al. Differences in grey and white matter atrophy in amnestic mild cognitive impairment and mild Alzheimer’s disease , 2009, European journal of neurology.
[78] J. O'Brien,et al. Microarray RNA Expression Analysis of Cerebral White Matter Lesions Reveals Changes in Multiple Functional Pathways , 2009, Stroke.
[79] Lawrence R. Frank,et al. Decreased white matter integrity in late-myelinating fiber pathways in Alzheimer's disease supports retrogenesis , 2009, NeuroImage.
[80] B. Fischl,et al. White matter pathology isolates the hippocampal formation in Alzheimer's disease , 2010, Neurobiology of Aging.
[81] J. Sloane,et al. Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2 , 2010, Proceedings of the National Academy of Sciences.
[82] Anders H. Andersen,et al. Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease , 2010, NeuroImage.
[83] Kai Zhang,et al. Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport , 2010, Science.
[84] Deborah A. Ryan,et al. Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. , 2010, The American journal of pathology.
[85] G. Halliday,et al. Focal demyelination in Alzheimer’s disease and transgenic mouse models , 2010, Acta Neuropathologica.
[86] Jürgen Götz,et al. Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models , 2010, Cell.
[87] Kuncheng Li,et al. Voxel-based assessment of gray and white matter volumes in Alzheimer's disease , 2010, Neuroscience Letters.
[88] In Chan Song,et al. Posterior cingulate cortex atrophy and regional cingulum disruption in mild cognitive impairment and Alzheimer's disease , 2010, Neurobiology of Aging.
[89] Vascular cognitive impairment: introduction. , 2004, Stroke.
[90] D. Wilcock,et al. Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease , 2010, Neuroscience.
[91] Guy B. Williams,et al. Absolute diffusivities define the landscape of white matter degeneration in Alzheimer's disease. , 2010, Brain : a journal of neurology.
[92] C. Jack,et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade , 2010, The Lancet Neurology.
[93] W. Brown,et al. Review: Cerebral microvascular pathology in ageing and neurodegeneration , 2011, Neuropathology and applied neurobiology.
[94] L. Mucke,et al. Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease , 2011, The Journal of Neuroscience.
[95] T. Montine,et al. White matter lesions defined by diffusion tensor imaging in older adults , 2011, Annals of neurology.
[96] Klaus P. Ebmeier,et al. The APOE ɛ4 allele modulates brain white matter integrity in healthy adults , 2011, Molecular Psychiatry.
[97] Meaghan Morris,et al. The Many Faces of Tau , 2011, Neuron.
[98] B. Delatour,et al. Fiber Tracts Anomalies in APPxPS1 Transgenic Mice Modeling Alzheimer's Disease , 2011, Journal of aging research.
[99] Massimo Filippi,et al. White matter damage in Alzheimer disease and its relationship to gray matter atrophy. , 2011, Radiology.
[100] K. Hwang,et al. Regional white matter hyperintensities in normal aging, single domain amnestic mild cognitive impairment, and mild Alzheimer’s disease , 2011, Journal of Clinical Neuroscience.
[101] J. Molinuevo,et al. Multiple DTI index analysis in normal aging, amnestic MCI and AD. Relationship with neuropsychological performance , 2012, Neurobiology of Aging.
[102] Simone Reppermund,et al. Abnormalities of the fornix in mild cognitive impairment are related to episodic memory loss. , 2012, Journal of Alzheimer's disease : JAD.
[103] Lin Zhuang,et al. Microstructural white matter changes in cognitively normal individuals at risk of amnestic MCI , 2012, Neurology.
[104] D. Y. Lee,et al. Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer’s Disease , 2012, Front. Ag. Neurosci..
[105] Takayuki Itoh,et al. Amyloid β1–42 oligomer inhibits myelin sheet formation in vitro , 2012, Neurobiology of Aging.
[106] C Caltagirone,et al. White matter damage along the uncinate fasciculus contributes to cognitive decline in AD and DLB. , 2012, Current Alzheimer research.
[107] Anders M. Fjell,et al. White matter imaging changes in subjective and mild cognitive impairment , 2012, Alzheimer's & Dementia.
[108] Igor O. Korolev,et al. Disruption of limbic white matter pathways in mild cognitive impairment and Alzheimer's disease: A DTI/FDG‐PET Study , 2012, Human brain mapping.
[109] M. Götz,et al. Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men , 2013, Glia.
[110] L. Mucke,et al. Amyloid-beta / Fyn – Induced Synaptic , Network , and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer ’ s Disease , 2015 .