The Effect of EHDP on the Allogenic Bone Graft in Rats

The effects of EHDP on the healing process of bone graft in rats tibia were observed roentgenographically and histologically. In the control and the treatment group with EHDP of 0. 5 mg/kg/day, remodelling of the callus was found, wheas it was not found in the group with EHDP of 1. 0 mg/day. In the groups with EHDP of 5 mg/kg/day and 30 mg/kg/day, the mineraliztion and calcification of the callus were strongly inhibited.

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