Semiparametric Analysis for Additive Risk Model via Empirical Likelihood

ABSTRACT Cox's proportional hazards model has been the most popular model for the regression analysis of censored survival data. However, the additive risk model provides a useful alternative. In this article, we apply the empirical likelihood ratio method to the additive risk model with right censoring and derive its limiting distribution. Based on the result, we construct a confidence region for the regression parameter. Useful extensions are discussed. Simulation results are presented to compare the proposed method with that method based on normal approximation.

[1]  Song Xi Chen,et al.  Empirical Likelihood Confidence Intervals for Linear Regression Coefficients , 1994 .

[2]  Ian W. McKeague,et al.  Weighted Least Squares Estimation for Aalen's Additive Risk Model , 1991 .

[3]  Xiaotong Shen,et al.  Empirical Likelihood , 2002 .

[4]  David R. Cox,et al.  Regression models and life tables (with discussion , 1972 .

[5]  O. Aalen A linear regression model for the analysis of life times. , 1989, Statistics in medicine.

[6]  Art B. Owen,et al.  Empirical Likelihood for Linear Models , 1991 .

[7]  Jian Shi,et al.  Empirical Likelihood for Partially Linear Models , 2000 .

[8]  Zhiliang Ying,et al.  Semiparametric Analysis of General Additive-Multiplicative Hazard Models for Counting Processes , 1995 .

[9]  Mei‐jie Zhang,et al.  An Additive–Multiplicative Cox–Aalen Regression Model , 2002 .

[10]  Gang Li,et al.  EMPIRICAL LIKELIHOOD REGRESSION ANALYSIS FOR RIGHT CENSORED DATA , 2003 .

[11]  Hengjian Cui,et al.  AN EXTENDED EMPIRICAL LIKELIHOOD FOR GENERALIZED LINEAR MODELS , 2003 .

[12]  S. Cheng,et al.  Confidence Bands for Cumulative Incidence Curves Under the Additive Risk Model , 1999, Biometrics.

[13]  Bing-Yi Jing,et al.  Empirical Likelihood for Censored Linear Regression , 2001 .

[14]  Zhiliang Ying,et al.  Additive hazards regression with current status data , 1998 .

[15]  Bing-Yi Jing,et al.  EMPIRICAL LIKELIHOOD FOR COX REGRESSION MODEL UNDER RANDOM CENSORSHIP , 2001 .

[16]  Bing-Yi Jing,et al.  Censored Partial Linear Models and Empirical Likelihood , 2001 .

[17]  J. N. K. Rao,et al.  Empirical Likelihood‐based Inference in Linear Models with Missing Data , 2002 .

[18]  Odd Aalen,et al.  A Model for Nonparametric Regression Analysis of Counting Processes , 1980 .

[19]  Myles Hollander,et al.  Likelihood Ratio-Based Confidence Bands for Survival Functions , 1997 .

[20]  Gang Li,et al.  On nonparametric likelihood ratio estimation of survival probabilities for censored data , 1995 .

[21]  Rupert G. Miller,et al.  Regression with censored data , 1982 .

[22]  A. Owen Empirical Likelihood Ratio Confidence Regions , 1990 .

[23]  Ian W. McKeague,et al.  A partly parametric additive risk model , 1994 .

[24]  Bing-Yi Jing,et al.  Empirical likelihood for partial linear models with fixed designs , 1999 .

[25]  Gang Li,et al.  Empirical Likelihood Semiparametric Regression Analysis under Random Censorship , 2002 .

[26]  Gang Li,et al.  Likelihood ratio confidence bands in non-parametric regression with censored data , 2002 .

[27]  Zhiliang Ying,et al.  Semiparametric analysis of the additive risk model , 1994 .

[28]  A. Owen Empirical likelihood ratio confidence intervals for a single functional , 1988 .

[29]  Mei-Jie Zhang,et al.  Extensions and Applications of the Cox‐Aalen Survival Model , 2003, Biometrics.

[30]  Mei-Cheng Wang,et al.  Additive Hazards Models with Latent Treatment Effectiveness Lag Time , 2002 .

[31]  DavidR . Thomas,et al.  Confidence Interval Estimation of Survival Probabilities for Censored Data , 1975 .

[32]  J. Buckley Additive and multiplicative models for relative survival rates. , 1984, Biometrics.

[33]  Song Xi Chen,et al.  On the accuracy of empirical likelihood confidence regions for linear regression model , 1993 .

[34]  J. N. K. Rao,et al.  Empirical likelihood for linear regression models under imputation for missing responses , 2001 .

[35]  Buckley Jd,et al.  Additive and multiplicative models for relative survival rates. , 1984 .

[36]  Ian W. McKeague,et al.  Simultaneous confidence bands for ratios of survival functions via empirical likelihood , 2002 .

[37]  Ian W. McKeague,et al.  CONFIDENCE TUBES FOR MULTIPLE QUANTILE PLOTS VIA EMPIRICAL LIKELIHOOD , 1999 .