Feasibility of GPU-assisted iterative image reconstruction for mobile C-arm CT

Computed tomography (CT) has been extensively studied and widely used for a variety of medical applications. The reconstruction of 3D images from a projection series is an important aspect of the modality. Reconstruction by filtered backprojection (FBP) is used by most manufacturers because of speed, ease of implementation, and relatively few parameters. Iterative reconstruction methods have a significant potential to provide superior performance with incomplete or noisy data, or with less than ideal geometries, such as cone-beam systems. However, iterative methods have a high computational cost, and regularization is usually required to reduce the effects of noise. The simultaneous algebraic reconstruction technique (SART) is studied in this paper, where the Feldkamp method (FDK) for filtered back projection is used as an initialization for iterative SART. Additionally, graphics hardware is utilized to increase the speed of SART implementation. Nvidia processors and compute unified device architecture (CUDA) form the platform for GPU computation. Total variation (TV) minimization is applied for the regularization of SART results. Preliminary results of SART on 3-D Shepp-Logan phantom using using TV regularization and GPU computation are presented in this paper. Potential improvements of the proposed framework are also discussed.