论文信息 - Intramolecular Cyclization of Mannich Reaction for Synthesis of Pyrimido[2,1-b]-1,3,5-thiadiazines.

Intramolecular Cyclization of Mannich Reaction for Synthesis of Pyrimido[2,1-b]-1,3,5-thiadiazines.

Reaction of 2-mercaptodihydropyrimidinones (I) with primary amines and formaldehyde in suitable solvent yields pyrimidothiadizinones (IV) (35 examples) via a double Mannich reaction.

A. EL-Mahdy | Z. A. Hozien | A. Sarhan | H. El-Sherief

[1] A. EL-Mahdy,et al. Intramolecular cyclization of Mannich reaction for synthesis of pyrimido[2,1‐b]‐1,3,5‐tiadiazines , 2010 .