Mitochondria Associated Membranes (MAMs): Architecture and physiopathological role.

[1]  Yujie Sun,et al.  ER-mitochondria contacts promote mtDNA nucleoids active transportation via mitochondrial dynamic tubulation , 2020, Nature Communications.

[2]  S. Colombo,et al.  Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity , 2020, Proceedings of the National Academy of Sciences.

[3]  F. Bost,et al.  Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites , 2020, Nature Communications.

[4]  I. Georgakoudi,et al.  Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival , 2020, Science Signaling.

[5]  E. Clementi,et al.  Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy , 2020, Cell Death & Differentiation.

[6]  P. Mercier,et al.  The ER chaperone calnexin controls mitochondrial positioning and respiration , 2020, Science Signaling.

[7]  Chao Tong,et al.  Endoplasmic Reticulum–Mitochondria Contact Sites and Neurodegeneration , 2020, Frontiers in Cell and Developmental Biology.

[8]  Taki Nishimura,et al.  Emerging roles of ATG proteins and membrane lipids in autophagosome formation , 2020, Cell Discovery.

[9]  M. Brini,et al.  PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease , 2020, International journal of molecular sciences.

[10]  P. Pinton,et al.  Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective. , 2020, Seminars in cell & developmental biology.

[11]  Alan R. Lowe,et al.  Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery , 2019, Nature Communications.

[12]  B. Brüne,et al.  ER-Mitochondria Communication in Cells of the Innate Immune System , 2019, Cells.

[13]  M. Brini,et al.  splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants , 2019, Cells.

[14]  I. Bezprozvanny,et al.  Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases , 2019, Front. Neurosci..

[15]  K. Min,et al.  Increased ER–mitochondria tethering promotes axon regeneration , 2019, Proceedings of the National Academy of Sciences.

[16]  A. Udristioiu,et al.  Autophagy dysfunctions associated with cancer cells and their therapeutic implications. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[17]  T. Wollert Autophagy , 2019, Current Biology.

[18]  J. Rieusset,et al.  Differential Effect of Glucose on ER-Mitochondria Ca2+ Exchange Participates in Insulin Secretion and Glucotoxicity-Mediated Dysfunction of β-Cells , 2019, Diabetes.

[19]  T. Namba,et al.  BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites , 2019, Science Advances.

[20]  K. Belosludtsev,et al.  Mitochondrial Ca2+ Transport: Mechanisms, Molecular Structures, and Role in Cells , 2019, Biochemistry (Moscow).

[21]  Hyunmi Kim,et al.  Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes , 2019, Acta Neuropathologica Communications.

[22]  J. Ting,et al.  The NLRP3 inflammasome: molecular activation and regulation to therapeutics , 2019, Nature Reviews Immunology.

[23]  C. M. Eischen,et al.  Targeting the Bcl-2 Family in B Cell Lymphoma , 2019, Front. Oncol..

[24]  Pedro Carvalho,et al.  Here, there, and everywhere: The importance of ER membrane contact sites , 2018, Science.

[25]  L. Héliot,et al.  4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer. , 2018, Biochimica et biophysica acta. Molecular cell research.

[26]  J. Baudier ATAD3 proteins: brokers of a mitochondria–endoplasmic reticulum connection in mammalian cells , 2018, Biological reviews of the Cambridge Philosophical Society.

[27]  P. Pinton,et al.  Calcium Dynamics as a Machine for Decoding Signals. , 2018, Trends in cell biology.

[28]  P. Pizzo,et al.  Mitofusin 2: from functions to disease , 2018, Cell Death & Disease.

[29]  S. Tooze,et al.  A molecular perspective of mammalian autophagosome biogenesis , 2018, The Journal of Biological Chemistry.

[30]  H. Higgs,et al.  INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division , 2018, The Journal of cell biology.

[31]  L. Scorrano,et al.  SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition , 2017, Cell Death & Differentiation.

[32]  C. Culmsee,et al.  Glucose-regulated protein 75 determines ER–mitochondrial coupling and sensitivity to oxidative stress in neuronal cells , 2017, Cell Death Discovery.

[33]  Yusuke Hirabayashi,et al.  ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons , 2017, Science.

[34]  S. Shinjo,et al.  Disruption of the mitochondria‐associated ER membrane (MAM) plays a central role in palmitic acid–induced insulin resistance , 2017, Experimental cell research.

[35]  P. Pinton,et al.  Regulation of Calcium Fluxes by GPX8, a Type-II Transmembrane Peroxidase Enriched at the Mitochondria-Associated Endoplasmic Reticulum Membrane. , 2017, Antioxidants & redox signaling.

[36]  L. Schoenfeld,et al.  Receptor-mediated Drp1 oligomerization on endoplasmic reticulum , 2017, bioRxiv.

[37]  J. Rieusset,et al.  Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes , 2017, PloS one.

[38]  T. Simmen,et al.  Endoplasmic reticulum chaperones tweak the mitochondrial calcium rheostat to control metabolism and cell death. , 2017, Cell calcium.

[39]  L. Galluzzi,et al.  Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C‐ring conformation , 2017, EMBO reports.

[40]  Jun Li,et al.  Comparative Proteomic Analysis of the Mitochondria-associated ER Membrane (MAM) in a Long-term Type 2 Diabetic Rodent Model , 2017, Scientific Reports.

[41]  Stephanie S. Lam,et al.  Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation , 2017, eLife.

[42]  Michael J. Devine,et al.  α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production , 2017, Acta Neuropathologica.

[43]  A. Luini,et al.  On the role of Mitofusin 2 in endoplasmic reticulum–mitochondria tethering , 2017, Proceedings of the National Academy of Sciences.

[44]  E. Valente,et al.  PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation , 2017, Autophagy.

[45]  Yu Zhu,et al.  MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling , 2017, Scientific Reports.

[46]  W. Noble,et al.  The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy , 2017, Current Biology.

[47]  Bernd Fischer,et al.  Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses , 2016, Cell Host & Microbe.

[48]  P. Pandolfi,et al.  PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development , 2016, Cell reports.

[49]  S. Janssens,et al.  ER–Mitochondria contact sites: A new regulator of cellular calcium flux comes into play , 2016, The Journal of cell biology.

[50]  P. Várnai,et al.  Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface. , 2016, Molecular cell.

[51]  J. Nunnari,et al.  ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells , 2016, Science.

[52]  C. Shaw,et al.  ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations , 2016, EMBO reports.

[53]  A. Luini,et al.  Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2. , 2016, Cell reports.

[54]  L. Scorrano,et al.  Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice , 2016, Scientific Reports.

[55]  Wenxian Wu,et al.  FUNDC1 regulates mitochondrial dynamics at the ER–mitochondrial contact site under hypoxic conditions , 2016, The EMBO journal.

[56]  G. Drin,et al.  New molecular mechanisms of inter-organelle lipid transport. , 2016, Biochemical Society transactions.

[57]  P. Agostinis,et al.  ORP5/ORP8 localize to endoplasmic reticulum–mitochondria contacts and are involved in mitochondrial function , 2016, EMBO reports.

[58]  A. Rosato,et al.  The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α , 2016, EMBO molecular medicine.

[59]  J. Diehl,et al.  Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria. , 2016, Cell reports.

[60]  P. Pinton,et al.  Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants , 2016, Front. Oncol..

[61]  T. Wai,et al.  Mitochondrial Dynamics and Metabolic Regulation , 2016, Trends in Endocrinology & Metabolism.

[62]  M. Binder,et al.  Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus , 2015, PLoS pathogens.

[63]  J. Rieusset,et al.  Contribution of mitochondria and endoplasmic reticulum dysfunction in insulin resistance: Distinct or interrelated roles? , 2015, Diabetes & metabolism.

[64]  H. McBride,et al.  MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death. , 2015, Molecular cell.

[65]  A. Lang,et al.  Parkinson's disease , 2015, The Lancet.

[66]  J. Lippincott-Schwartz,et al.  A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division , 2015, eLife.

[67]  I. Nabi,et al.  Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria , 2015, Journal of Cell Science.

[68]  Justin Yamada,et al.  Ltc1 is an ER-localized sterol transporter and a component of ER–mitochondria and ER–vacuole contacts , 2015, The Journal of cell biology.

[69]  P. Pinton,et al.  SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity. , 2015, Human molecular genetics.

[70]  H. Bose,et al.  Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction* , 2014, The Journal of Biological Chemistry.

[71]  F. Mammano,et al.  Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling , 2014, Oncotarget.

[72]  G. Hotamisligil,et al.  Chronic enrichment of hepatic ER-mitochondria contact sites leads to calcium dependent mitochondrial dysfunction in obesity , 2014, Nature medicine.

[73]  M. Ankarcrona,et al.  Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes. , 2014, Journal of Alzheimer's disease : JAD.

[74]  R. Kaufman,et al.  Calcium trafficking integrates endoplasmic reticulum function with mitochondrial bioenergetics. , 2014, Biochimica et biophysica acta.

[75]  F. Zoulim,et al.  Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance , 2014, Diabetes.

[76]  P. Pinton,et al.  Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes , 2014, Molecular & cellular oncology.

[77]  L. Petrucelli,et al.  ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 , 2014, Nature Communications.

[78]  P. Pinton,et al.  The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications , 2014, The Journal of physiology.

[79]  E. Schon,et al.  α-Synuclein Is Localized to Mitochondria-Associated ER Membranes , 2014, The Journal of Neuroscience.

[80]  C. Coyne,et al.  Regulation of Mitochondrial Antiviral Signaling (MAVS) Expression and Signaling by the Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Protein Gp78* , 2013, The Journal of Biological Chemistry.

[81]  H. Ouadid‐Ahidouch,et al.  Molecular interaction and functional coupling between type 3 inositol 1,4,5-trisphosphate receptor and BKCa channel stimulate breast cancer cell proliferation. , 2013, European journal of cancer.

[82]  T. Ichinohe,et al.  Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection , 2013, Proceedings of the National Academy of Sciences.

[83]  D. Cleveland,et al.  Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis , 2013, Neuron.

[84]  T. Yoshimori,et al.  Up-to-date membrane biogenesis in the autophagosome formation. , 2013, Current opinion in cell biology.

[85]  N. Demaurex,et al.  From the Cover: Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology , 2013 .

[86]  H. McBride,et al.  MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2. , 2013, Molecular cell.

[87]  P. Pandolfi,et al.  Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner , 2013, Cell Death and Differentiation.

[88]  A. Negro,et al.  The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum-mitochondria tethering. , 2013, Human molecular genetics.

[89]  B. Winblad,et al.  Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models , 2013, Proceedings of the National Academy of Sciences.

[90]  R. Germain,et al.  The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation , 2013, Cell.

[91]  A. Negro,et al.  Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics. , 2013, Biochimica et biophysica acta.

[92]  Carthene R. Bazemore-Walker,et al.  In-depth proteomic analysis of mammalian mitochondria-associated membranes (MAM). , 2013, Journal of proteomics.

[93]  F. Althaus,et al.  Cytosolic Ca2+ shifts as early markers of cytotoxicity , 2013, Cell Communication and Signaling.

[94]  H. Higgs,et al.  An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2 , 2013, Science.

[95]  S. Kakinuma,et al.  Hepatitis C virus NS4B protein targets STING and abrogates RIG‐I–mediated type I interferon‐dependent innate immunity , 2013, Hepatology.

[96]  S. Aguirre,et al.  DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING , 2012, PLoS pathogens.

[97]  S. Lev Nonvesicular lipid transfer from the endoplasmic reticulum. , 2012, Cold Spring Harbor perspectives in biology.

[98]  G. Voeltz,et al.  Endoplasmic reticulum–mitochondria contacts: function of the junction , 2012, Nature Reviews Molecular Cell Biology.

[99]  J. Nunnari,et al.  Mitochondrial Dynamics and Apoptosis—the ER Connection , 2012, Science.

[100]  A. M. van der Bliek,et al.  Mitochondrial Fission, Fusion, and Stress , 2012, Science.

[101]  E. Schon,et al.  Upregulated function of mitochondria-associated ER membranes in Alzheimer disease , 2012, The EMBO journal.

[102]  A. Al-Chalabi,et al.  The genetics and neuropathology of amyotrophic lateral sclerosis , 2012, Acta Neuropathologica.

[103]  P. Pinton,et al.  Mitochondrial Ca2+ and apoptosis , 2012, Cell calcium.

[104]  P. Pinton,et al.  Ero1α regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM). , 2012, Antioxidants & redox signaling.

[105]  M. Hall,et al.  Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. , 2012, Cell metabolism.

[106]  P. Pinton,et al.  Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis , 2012, Cell Death and Disease.

[107]  A. Basu,et al.  STING Mediates Neuronal Innate Immune Response Following Japanese Encephalitis Virus Infection , 2012, Scientific Reports.

[108]  A. Negro,et al.  α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions* , 2012, The Journal of Biological Chemistry.

[109]  M. Orešič,et al.  Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis , 2012, Proceedings of the National Academy of Sciences.

[110]  S. Grimm The ER-mitochondria interface: the social network of cell death. , 2012, Biochimica et biophysica acta.

[111]  Teruo Hayashi,et al.  The role of cholesterol in the association of endoplasmic reticulum membranes with mitochondria. , 2012, Biochemical and biophysical research communications.

[112]  C. Shaw,et al.  VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis , 2011, Human molecular genetics.

[113]  Matthew West,et al.  ER Tubules Mark Sites of Mitochondrial Division , 2011, Science.

[114]  Carlotta Giorgi,et al.  Calcium signaling around Mitochondria Associated Membranes (MAMs) , 2011, Cell Communication and Signaling.

[115]  M. Gale,et al.  Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus , 2011, Proceedings of the National Academy of Sciences.

[116]  A. Messina,et al.  VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria , 2011, Cell Death and Differentiation.

[117]  G. Shore,et al.  Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum , 2011, The EMBO journal.

[118]  S. Grimm,et al.  Fis1 and Bap31 bridge the mitochondria–ER interface to establish a platform for apoptosis induction , 2011, The EMBO journal.

[119]  J. Tschopp,et al.  A role for mitochondria in NLRP3 inflammasome activation , 2011, Nature.

[120]  Benedikt Westermann,et al.  Mitochondrial fusion and fission in cell life and death , 2010, Nature Reviews Molecular Cell Biology.

[121]  S. Weber,et al.  The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations , 2010, Autophagy.

[122]  R. Schwarzenbacher,et al.  Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization , 2010, Cell.

[123]  Terry K. Smith,et al.  The Kennedy pathway—De novo synthesis of phosphatidylethanolamine and phosphatidylcholine , 2010, IUBMB life.

[124]  Peter K. Kim,et al.  Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation , 2010, Cell.

[125]  Y. Hannun,et al.  Identification and Characterization of Murine Mitochondria-associated Neutral Sphingomyelinase (MA-nSMase), the Mammalian Sphingomyelin Phosphodiesterase 5* , 2010, The Journal of Biological Chemistry.

[126]  Teruo Hayashi,et al.  Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction , 2010, Molecular Pharmacology.

[127]  Teruo Hayashi,et al.  Sigma-1 Receptors Regulate Bcl-2 Expression by Reactive Oxygen Species-Dependent Transcriptional Regulation of Nuclear Factor κB , 2010, Journal of Pharmacology and Experimental Therapeutics.

[128]  A. MacAskill,et al.  Control of mitochondrial transport and localization in neurons. , 2010, Trends in cell biology.

[129]  Atsushi Tanaka,et al.  PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin , 2010, PLoS biology.

[130]  A. Shalev,et al.  Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein* , 2009, The Journal of Biological Chemistry.

[131]  J. Opferman,et al.  GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis. , 2009, Molecular cell.

[132]  E. Schon,et al.  Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. , 2009, The American journal of pathology.

[133]  Carlotta Giorgi,et al.  Ca(2+) transfer from the ER to mitochondria: when, how and why. , 2009, Biochimica et biophysica acta.

[134]  M. Bootman,et al.  The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor , 2009, Proceedings of the National Academy of Sciences.

[135]  J. Nunnari,et al.  An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen , 2009, Science.

[136]  R. Rizzuto,et al.  Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress. , 2008, Molecular cell.

[137]  L. Scorrano,et al.  Mitofusin 2 tethers endoplasmic reticulum to mitochondria , 2008, Nature.

[138]  Y. Li,et al.  The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. , 2008, Immunity.

[139]  G. D’Angelo,et al.  Lipid-transfer proteins in biosynthetic pathways. , 2008, Current opinion in cell biology.

[140]  T. Simmen,et al.  The subcellular distribution of calnexin is mediated by PACS-2. , 2008, Molecular biology of the cell.

[141]  David J Stephens,et al.  Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation. , 2008, Molecular biology of the cell.

[142]  D. Clapham,et al.  Calcium Signaling , 2007, Cell.

[143]  D. Chan,et al.  Functions and dysfunctions of mitochondrial dynamics , 2007, Nature Reviews Molecular Cell Biology.

[144]  P. Várnai,et al.  Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels , 2006, The Journal of cell biology.

[145]  S. Kahn,et al.  Mechanisms linking obesity to insulin resistance and type 2 diabetes , 2006, Nature.

[146]  M. Goedert,et al.  A Century of Alzheimer's Disease , 2006, Science.

[147]  R. Youle,et al.  Role of Bax and Bak in mitochondrial morphogenesis , 2006, Nature.

[148]  Y. Hannun,et al.  Bioactive sphingolipids in the modulation of the inflammatory response. , 2006, Pharmacology & therapeutics.

[149]  C. Mannella,et al.  Structural and functional features and significance of the physical linkage between ER and mitochondria , 2006, The Journal of cell biology.

[150]  L. Scorrano,et al.  The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis. , 2006, Molecular biology of the cell.

[151]  C. Thompson,et al.  The endoplasmic reticulum gateway to apoptosis by Bcl-XL modulation of the InsP3R , 2005, Nature Cell Biology.

[152]  Zhijian J. Chen,et al.  Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3 , 2005, Cell.

[153]  B. Schermer,et al.  Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation , 2005, The EMBO journal.

[154]  L. Wan,et al.  PACS‐2 controls endoplasmic reticulum–mitochondria communication and Bid‐mediated apoptosis , 2005, The EMBO journal.

[155]  D. Guertin,et al.  Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex , 2005, Science.

[156]  M. Oshimura,et al.  PI3K-Akt pathway: Its functions and alterations in human cancer , 2004, Apoptosis.

[157]  R. Rizzuto,et al.  Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis. , 2004, Molecular cell.

[158]  Jian Feng,et al.  Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis. , 2004, Human molecular genetics.

[159]  L. Bruijn,et al.  Unraveling the mechanisms involved in motor neuron degeneration in ALS. , 2004, Annual review of neuroscience.

[160]  D. Stojanovski,et al.  Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology , 2004, Journal of Cell Science.

[161]  M. Berridge,et al.  Calcium: Calcium signalling: dynamics, homeostasis and remodelling , 2003, Nature Reviews Molecular Cell Biology.

[162]  P. Lockhart,et al.  Parkin Protects against the Toxicity Associated with Mutant α-Synuclein Proteasome Dysfunction Selectively Affects Catecholaminergic Neurons , 2002, Neuron.

[163]  B. Hyman,et al.  Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid β-peptide , 2001, Nature Cell Biology.

[164]  S. Frank,et al.  The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. , 2001, Developmental cell.

[165]  Y. Tsujimoto,et al.  VDAC regulation by the Bcl-2 family of proteins , 2000, Cell Death and Differentiation.

[166]  Lawrence M. Lifshitz,et al.  Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. , 1998, Science.

[167]  S. Minoshima,et al.  Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.

[168]  G. Packham,et al.  Mutation of BCL-2 Family Proteins in Cancer , 1998, Apoptosis.

[169]  J. Vance Phospholipid synthesis in a membrane fraction associated with mitochondria. , 1990, The Journal of biological chemistry.

[170]  D. Copeland,et al.  An Association between Mitochondria and the Endoplasmic Reticulum in Cells of the Pseudobranch Gland of a Teleost , 1959, The Journal of biophysical and biochemical cytology.

[171]  P. Pinton,et al.  Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death. , 2018, Cell calcium.

[172]  P. Pinton,et al.  Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs). , 2017, Advances in experimental medicine and biology.

[173]  A. Rothman,et al.  Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission. , 2017, Virology.

[174]  J. Rieusset Role of Endoplasmic Reticulum-Mitochondria Communication in Type 2 Diabetes. , 2017, Advances in experimental medicine and biology.

[175]  V. Papadopoulos,et al.  Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3. , 2015, Endocrinology.

[176]  T. Simmen,et al.  Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM). , 2013, Biochimica et biophysica acta.

[177]  Vincenzo Bonifati,et al.  Autosomal recessive parkinsonism. , 2012, Parkinsonism & related disorders.

[178]  P. Pinton,et al.  Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units. , 2012, Advances in experimental medicine and biology.

[179]  Teruo Hayashi,et al.  New insights into the role of mitochondria-associated endoplasmic reticulum membrane. , 2011, International review of cell and molecular biology.

[180]  R. Youle,et al.  Mechanisms of mitophagy , 2010, Nature Reviews Molecular Cell Biology.

[181]  M. Cookson,et al.  Genetic neuropathology of Parkinson's disease. , 2008, International journal of clinical and experimental pathology.

[182]  A. Karakashian,et al.  Role of neutral sphingomyelinases in aging and inflammation. , 2008, Sub-cellular biochemistry.