Dynamic knee stability: current theory and implications for clinicians and scientists.

We will discuss the mechanisms by which dynamic knee stability may be achieved and relate this to issues that interest clinicians and scientists concerned with dynamic knee stability. Emphasis is placed on the neurophysiologic evidence and theory related to neuromuscular control. Specific topics discussed include the ensemble firing of peripheral mechanoreceptors, the potential for muscle stiffness modulation via force and length feedback, postural control synergies, motor programs, and the neural control of gait. Factors related to answering the difficult question of whether or not knee ligament injuries can be prevented during athletic activities are discussed. Prevention programs that train athletes to perform their sport skills in a safe fashion are put forth as the most promising prospect for injury prevention. Methods of assessing neuromuscular function are reviewed critically and the need for future research in this area is emphasized. We conclude with a brief review of the literature regarding neuromuscular training programs.

[1]  M. Alexander,et al.  Principles of Neural Science , 1981 .

[2]  D. Burke,et al.  Responses to passive movement of receptors in joint, skin and muscle of the human hand. , 1988, The Journal of physiology.

[3]  P. Grigg,et al.  Responses of rapidly adapting afferent neurons to dynamic stretch of rat hairy skin. , 1998, Journal of neurophysiology.

[4]  W E Garrett,et al.  The anterior cruciate ligament enigma. Injury mechanisms and prevention. , 2000, Clinical orthopaedics and related research.

[5]  D. Hedden,et al.  Proprioception in Anterior Cruciate Ligament-Deficient and Reconstructed Knees , 1996, The American journal of sports medicine.

[6]  H. Schaible,et al.  Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint. , 1983, Journal of neurophysiology.

[7]  H Johansson,et al.  Actions on gamma‐motoneurones elicited by electrical stimulation of joint afferent fibres in the hind limb of the cat. , 1986, The Journal of physiology.

[8]  Scott M. Lephart,et al.  Proprioception and neuromuscular control in joint stability , 2000 .

[9]  H. Skinner,et al.  Proprioception in the anterior cruciate deficient knee , 1989, The American journal of sports medicine.

[10]  A. Caraffa,et al.  Prevention of anterior cruciate ligament injuries in soccer , 1996, The Journal of orthopaedic and sports physical therapy.

[11]  T. Jenkinson,et al.  Joint position sense and rehabilitation in the anterior cruciate ligament deficient knee. , 1997, British journal of sports medicine.

[12]  D. Burke,et al.  Perceptual responses to microstimulation of single afferents innervating joints, muscles and skin of the human hand. , 1990, The Journal of physiology.

[13]  L. Huston,et al.  Neuromuscular Performance in Normal and Anterior Cruciate Ligament-Deficient Lower Extremities , 1994, The American journal of sports medicine.

[14]  Contralateral hamstring (biceps femoris) coactivation patterns and anterior cruciate ligament dysfunction. , 1995, Medicine and science in sports and exercise.

[15]  J. O'Connor,et al.  Can muscle co-contraction protect knee ligaments after injury or repair? , 1993, The Journal of bone and joint surgery. British volume.

[16]  Per Sjölander,et al.  Fusimotor reflexes in triceps surae muscle elicited by natural and electrical stimulation of joint afferents , 1988 .

[17]  Per Sjölander,et al.  Fusimotor neurones can be reflexy influenced by activity in receptor afferents from the posterior cruciate ligament , 1989, Brain Research.

[18]  P. Katonis,et al.  Mechanoreceptors in the posterior cruciate ligament. Histologic study on cadaver knees. , 1991, Acta orthopaedica Scandinavica.

[19]  C A Morehouse,et al.  Effect of muscular tension on knee stability. , 1973, Medicine and science in sports.

[20]  Per Sjölander,et al.  Fusimotor reflexes to antagonistic muscles simultaneously assessed by multi-afferent recordings from muscle spindle afferents , 1987, Brain Research.

[21]  A. Lindstrand,et al.  Proprioception in people with anterior cruciate ligament-deficient knees: comparison of symptomatic and asymptomatic patients. , 1999, The Journal of orthopaedic and sports physical therapy.

[22]  Freddie H. Fu,et al.  Determination of the in situ loads on the human anterior cruciate ligament , 1993, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[23]  M. Hulliger,et al.  The responses of afferent fibres from the glabrous skin of the hand during voluntary finger movements in man. , 1979, The Journal of physiology.

[24]  David L. Butler,et al.  Biomechanics of the Anterior Cruciate Ligament and its Replacements , 1990 .

[25]  I. A. Boyd,et al.  Proprioceptive discharges from stretch‐receptors in the knee‐joint of the cat , 1953, The Journal of physiology.

[26]  S M Lephart,et al.  Knee Joint Laxity and Neuromuscular Characteristics of Male and Female Soccer and Basketball Players , 1999, The American journal of sports medicine.

[27]  Freddie H. Fu,et al.  Importance of the medial meniscus in the anterior cruciate ligament‐deficient knee , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[28]  A. Lindstrand,et al.  Proprioceptive defects after an anterior cruciate ligament rupture – the relation to associated anatomical lesions and subjective knee function , 1999, Knee Surgery, Sports Traumatology, Arthroscopy.

[29]  H B Skinner,et al.  Joint position sense in the normal and pathologic knee joint. , 1991, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[30]  T A Abelew,et al.  Rapid spinal mechanisms of motor coordination. , 1999, Exercise and sport sciences reviews.

[31]  B. Beynnon,et al.  The Effect of Anterior Cruciate Ligament Trauma and Bracing on Knee Proprioception , 1999, The American journal of sports medicine.

[32]  J. D. Withrow,et al.  Biomechanics of Knee Ligaments , 1993, The American journal of sports medicine.

[33]  H. Skinner,et al.  Effect of articular disease and total knee arthroplasty on knee joint-position sense. , 1983, Journal of neurophysiology.

[34]  J. Houk,et al.  Regulatory actions of human stretch reflex. , 1976, Journal of neurophysiology.

[35]  P. Matthews Evolving views on the internal operation and functional role of the muscle spindle. , 1981, The Journal of physiology.

[36]  T. Nichols,et al.  The role of musculoskeletal mechanics in motor coordination. , 1999, Progress in brain research.

[37]  T. Buchanan,et al.  Selective muscle activation following rapid varus/valgus perturbations at the knee. , 1996, Medicine and science in sports and exercise.

[38]  S M Lephart,et al.  Muscle preactivity of anterior cruciate ligament-deficient and -reconstructed females during functional activities. , 1999, Journal of athletic training.

[39]  M. Axe,et al.  Proposed practice guidelines for nonoperative anterior cruciate ligament rehabilitation of physically active individuals. , 2000, The Journal of orthopaedic and sports physical therapy.

[40]  J. Kehne The Neural Basis of Motor Control , 1987, The Yale Journal of Biology and Medicine.

[41]  S. Bouisset,et al.  [Voluntary movement]. , 1953, Journal de physiologie.

[42]  R. Vanderby,et al.  Hamstrings and gastrocnemius co-contraction protects the anterior cruciate ligament against failure: an in vivo study in the rat. , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[43]  F. Noyes,et al.  BIOMECHANICS OF LIGAMENTS AND TENDONS , 1978, Exercise and sport sciences reviews.

[44]  H. Johansson,et al.  Activity in receptor afferents from the anterior cruciate ligament evokes reflex effects on fusimotor neurones , 1990, Neuroscience Research.

[45]  Jamps C Houic Participation of Reflex Mechanisms and : Reaction-Time Processes in the Compensatory Adjustments to Mechanical Disturbances , 2022 .

[46]  S. Grillner Control of Locomotion in Bipeds, Tetrapods, and Fish , 1981 .

[47]  J. Parlange,et al.  Water uptake, diameter change, and nonlinear diffusion in tree stems. , 1975, Plant physiology.

[48]  H J Yack Further evidence against a direct automatic neuromotor link between the ACL and hamstrings. , 1993, Medicine and science in sports and exercise.

[49]  S. P. Evseev,et al.  The Control of Movement , 1996 .

[50]  S. Skoglund,et al.  On the reflex effects from the knee joint of the cat. , 1960, Acta physiologica Scandinavica.

[51]  T. Thach Neural Basis of Motor Control , 1993 .

[52]  E. Evarts Motor Cortex Reflexes Associated with Learned Movement , 1973, Science.

[53]  T. Hewett,et al.  Noncontact anterior cruciate ligament injuries: risk factors and prevention strategies. , 2000, The Journal of the American Academy of Orthopaedic Surgeons.

[54]  T S Buchanan,et al.  Selective muscle activation following electrical stimulation of the collateral ligaments of the human knee joint. , 1995, Archives of physical medicine and rehabilitation.

[55]  P. Grigg,et al.  Mechanical factors influencing response of joint afferent neurons from cat knee. , 1975, Journal of neurophysiology.

[56]  D. Burke,et al.  Does the nervous system depend on kinesthetic information to control natural limb movements , 1992 .

[57]  D. McCloskey,et al.  Kinaesthetic signals and muscle contraction , 1992, Trends in Neurosciences.

[58]  B. Edin,et al.  Skin strain patterns provide kinaesthetic information to the human central nervous system. , 1995, The Journal of physiology.

[59]  L. Good,et al.  Postural control — a comparison between patients with chronic anterior cruciate ligament insufficiency and healthy individuals , 1998, Scandinavian journal of medicine & science in sports.

[60]  K. Markolf,et al.  The role of joint load in knee stability. , 1981, The Journal of bone and joint surgery. American volume.

[61]  T. Sinkjaer,et al.  Muscle stiffness in human ankle dorsiflexors: intrinsic and reflex components. , 1988, Journal of neurophysiology.

[62]  J. Houk,et al.  Responses of Golgi tendon organs to active contractions of the soleus muscle of the cat. , 1967, Journal of neurophysiology.

[63]  A. Lindstrand,et al.  The Effect of Physiotherapy on Standing Balance in Chronic Anterior Cruciate Ligament Insufficiency , 1994, The American journal of sports medicine.

[64]  R. Warren,et al.  The Effect of Joint-Compressive Load and Quadriceps Muscle Force on Knee Motion in the Intact and Anterior Cruciate Ligament-Sectioned Knee , 1994, The American journal of sports medicine.

[65]  Muscle, reflex and central components in the control of the ankle joint in healthy and spastic man. , 1997, Acta neurologica Scandinavica. Supplementum.

[66]  H Tropp,et al.  Altered movement and muscular-activation patterns during the one-legged jump in patients with an old anterior cruciate ligament rupture , 1992, The American journal of sports medicine.

[67]  H. Johansson,et al.  Receptors in the knee joint ligaments and their role in the biomechanics of the joint. , 1991, Critical reviews in biomedical engineering.

[68]  B. Wyke,et al.  The innervation of the knee joint. An anatomical and histological study in the cat. , 1967, Journal of anatomy.

[69]  Timothy D. Lee,et al.  Motor Control and Learning: A Behavioral Emphasis , 1982 .

[70]  R. Shiavi,et al.  EMG profiles of knee joint musculature during walking: Changes induced by anterior cruciate ligament deficiency , 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[71]  H. Schaible,et al.  Sensory innervation of the anterior cruciate ligament. An electrophysiological study of the response properties of single identified mechanoreceptors in the cat. , 1992, The Journal of bone and joint surgery. American volume.

[72]  R. D'ambrosia,et al.  The synergistic action of the anterior cruciate ligament and thigh muscles in maintaining joint stability , 1987, The American journal of sports medicine.

[73]  S Grillner,et al.  Central pattern generators for locomotion, with special reference to vertebrates. , 1985, Annual review of neuroscience.

[74]  F. Girgis,et al.  The cruciate ligaments of the knee joint. Anatomical, functional and experimental analysis. , 1975, Clinical orthopaedics and related research.

[75]  A Prochazka,et al.  Ensemble firing of muscle afferents recorded during normal locomotion in cats , 1998, The Journal of physiology.

[76]  J. Houk,et al.  Improvement in linearity and regulation of stiffness that results from actions of stretch reflex. , 1976, Journal of neurophysiology.

[77]  J. Kennedy,et al.  Nerve supply of the human knee and its functional importance , 1982, The American journal of sports medicine.

[78]  A. Lindstrand,et al.  Early rehabilitation of acute anterior cruciate ligament injury—a randomized clinical trial , 1998, Scandinavian journal of medicine & science in sports.

[79]  Thomas Sinkjær,et al.  Altered timing of hamstring muscle action in anterior cruciate ligament deficient patients , 1990, The American journal of sports medicine.

[80]  H. Johansson,et al.  Influence from stretch-sensitive receptors in the collateral ligaments of the knee joint on the γ-muscle-spindle systems of flexor and extensor muscles , 1991, Neuroscience Research.

[81]  P. Grigg,et al.  Responses of mechanoreceptor neurons in the cat knee joint capsule before and after anterior cruciate ligament transection , 1996, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[82]  C D Mote,et al.  Contribution of the musculature to rotatory laxity and torsional stiffness at the knee. , 1987, Journal of biomechanics.

[83]  S. Woo,et al.  The importance of quadriceps and hamstring muscle loading on knee kinematics and in-situ forces in the ACL. , 1999, Journal of biomechanics.

[84]  M. Allen,et al.  Sports Injuries: Mechanisms, Prevention, Treatment , 2001 .

[85]  S. Grillner Locomotion in vertebrates: central mechanisms and reflex interaction. , 1975, Physiological reviews.

[86]  Van de Crommert HW,et al.  Neural control of locomotion; The central pattern generator from cats to humans. , 1998, Gait & posture.

[87]  H. V. D. Crommert,et al.  Neural control of locomotion: sensory control of the central pattern generator and its relation to treadmill training. , 1998, Gait & posture.

[88]  K. R. Campbell,et al.  Electromyographic study of the anterior cruciate ligament–hamstrings synergy during isometric knee extension , 1989, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[89]  F. Horak,et al.  Central programming of postural movements: adaptation to altered support-surface configurations. , 1986, Journal of neurophysiology.

[90]  W. Ferrell The adequacy of stretch receptors in the cat knee joint for signalling joint angle throughout a full range of movement. , 1980, The Journal of physiology.

[91]  S. Lephart,et al.  Proprioception of the Ankle and Knee , 1998, Sports medicine.

[92]  Musculoskeletal,et al.  Biology and biomechanics of the traumatized synovial joint : the knee as a model , 1992 .

[93]  A H Hoffman,et al.  Properties of Ruffini afferents revealed by stress analysis of isolated sections of cat knee capsule. , 1982, Journal of neurophysiology.

[94]  J. O'Connor,et al.  Reflex hamstring contraction latency in anterior cruciate ligament deficiency , 1994, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[95]  F. J. Clark,et al.  Characteristics of knee joint receptors in the cat , 1969, The Journal of physiology.

[96]  K. Markolf,et al.  The role of the meniscus in the anterior-posterior stability of the loaded anterior cruciate-deficient knee. Effects of partial versus total excision. , 1986, The Journal of bone and joint surgery. American volume.

[97]  B. Boden,et al.  Mechanisms of anterior cruciate ligament injury. , 2000, Orthopedics.

[98]  H Johansson,et al.  Actions on gamma‐motoneurones elicited by electrical stimulation of group I muscle afferent fibres in the hind limb of the cat. , 1983, The Journal of physiology.

[99]  P. Walker,et al.  Ligament length patterns, strength, and rotational axes of the knee joint. , 1976, Clinical orthopaedics and related research.

[100]  S. Grillner,et al.  Cellular network underlying locomotion as revealed in a lower vertebrate model: transmitters, membrane properties, circuitry, and simulation. , 1990, Cold Spring Harbor symposia on quantitative biology.

[101]  A. Lindstrand,et al.  Proprioception in the nearly extended knee. Measurements of position and movement in healthy individuals and in symptomatic anterior cruciate ligament injured patients. , 1996, Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA.

[102]  J. Desmedt Cerebral motor control in man : long loop mechanisms , 1978 .

[103]  W. Seering,et al.  The function of the primary ligaments of the knee in anterior-posterior and medial-lateral motions. , 1980, Journal of biomechanics.

[104]  J P Corrigan,et al.  Proprioception in the cruciate deficient knee. , 1992, The Journal of bone and joint surgery. British volume.

[105]  R. Petrella,et al.  THE EFFECT OF AGE AND ACTIVITY ON KNEE‐JOINT PROPRIOCEPTION , 1996, American journal of physical medicine & rehabilitation.

[106]  S. Lyman,et al.  The effect of neuromuscular training on the incidence of knee injury in female athletes: a prospective study. , 2000, The American journal of sports medicine.

[107]  Scott M. Lephart,et al.  Reestablishing Proprioception and Neuromuscular Control in the ACL-Injured Athlete , 1997 .

[108]  H. Skinner,et al.  Effect of fatigue on joint position sense of the knee , 1986, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[109]  R. Marshall,et al.  Landing characteristics in subjects with normal and anterior cruciate ligament deficient knee joints. , 1994, Archives of physical medicine and rehabilitation.

[110]  T. Sinkjaer,et al.  Muscle coordination following rupture of the anterior cruciate ligament. Electromyographic studies of 14 patients. , 1991, Acta orthopaedica Scandinavica.

[111]  R. Warren,et al.  The effect of medial meniscectomy on anterior-posterior motion of the knee. , 1982, The Journal of bone and joint surgery. American volume.

[112]  K. J. Cole,et al.  Physiologic loading of the anterior cruciate ligament does not activate quadriceps or hamstrings in the anesthetized cat , 1990, The American journal of sports medicine.

[113]  F. J. Clark,et al.  Slowly adapting receptors in cat knee joint: can they signal joint angle? , 1975, Journal of neurophysiology.

[114]  M G Carpenter,et al.  Postural control is scaled to level of postural threat. , 2000, Gait & posture.

[115]  S. Rossignol,et al.  Phase dependent reflex reversal during walking in chronic spinal cats , 1975, Brain Research.

[116]  E. Gardner The innervation of the knee joint , 1948, The Anatomical record.

[117]  T. Nichols Receptor mechanisms underlying heterogenic reflexes among the triceps surae muscles of the cat. , 1999, Journal of neurophysiology.

[118]  J Houk,et al.  Feedback control of skeletal muscles. , 1967, Brain research.

[119]  K. Pearson Proprioceptive regulation of locomotion , 1995, Current Opinion in Neurobiology.

[120]  M. Hulliger,et al.  The mammalian muscle spindle and its central control. , 1984, Reviews of physiology, biochemistry and pharmacology.

[121]  William S. Quillen,et al.  Athletic injuries and rehabilitation , 1996 .

[122]  I. A. Boyd,et al.  The histological structure of the receptors in the knee‐joint of the cat correlated with their physiological response , 1954, The Journal of physiology.

[123]  A. Simpson,et al.  Proprioception enhancement for anterior cruciate ligament deficiency. A prospective randomised trial of two physiotherapy regimes. , 1994, The Journal of bone and joint surgery. British volume.

[124]  Peter Grigg,et al.  Peripheral Neural Mechanisms in Proprioception , 1994 .

[125]  K. Froberg,et al.  Prevention of injuries in young female players in European team handball. A prospective intervention study , 1999, Scandinavian journal of medicine & science in sports.

[126]  William E. Garrett,et al.  Electromyographic and kinematic analysis of cutting maneuvers: implications for anterior cruciate ligament injury , 1999 .

[127]  H. Alfredson,et al.  Balance board training: prevention of traumatic injuries of the lower extremities in female soccer players? , 2000, Knee Surgery, Sports Traumatology, Arthroscopy.

[128]  H B Skinner,et al.  Joint position sense in total knee arthroplasty , 1984, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[129]  T. Hewett Neuromuscular and Hormonal Factors Associated With Knee Injuries in Female Athletes , 2000, Sports medicine.

[130]  The effect of mechanical stimulation of knee joint afferents on quadriceps motor unit activity in the decerebrate cat , 1987, Brain Research.

[131]  F. Girgis,et al.  The prime static stabilizer of the medical side of the knee. , 1974, The Journal of bone and joint surgery. American volume.

[132]  J. Duysens,et al.  Neural control of locomotion; Part 1: The central pattern generator from cats to humans , 1998 .

[133]  N. Friederich,et al.  Occurrence of free nerve endings in the soft tissue of the knee joint , 1992, The American journal of sports medicine.

[134]  D. Stuart,et al.  Ensemble characteristics of cat locomotion and its neural control. , 1982, Progress in neurobiology.

[135]  Z. Halata,et al.  The ultrastructure of the sensory nerve endings in the articular capsule of the knee joint of the domestic cat (Ruffini corpuscles and Pacinian corpuscles). , 1977, Journal of anatomy.

[136]  A. Lindstrand,et al.  Proprioception after an acute knee ligament injury: A longitudinal study on 16 consecutive patients , 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[137]  M. Hulliger,et al.  Ensemble proprioceptive activity in the cat step cycle: towards a representative look-up chart. , 1989, Progress in brain research.

[138]  Mark D. Miller,et al.  Biomechanics of knee ligaments: basic concepts and clinical application. , 1993, Instructional course lectures.

[139]  Marjorie H. Woollacott,et al.  Motor Control: Theory and Practical Applications , 1995 .

[140]  T. Nichols A biomechanical perspective on spinal mechanisms of coordinated muscular action: an architecture principle. , 1994, Acta anatomica.

[141]  M. Sager,et al.  Proprioception of the cruciate ligaments: receptor mapping in an animal model , 1998, Archives of Orthopaedic and Trauma Surgery.

[142]  M. Axe,et al.  The efficacy of perturbation training in nonoperative anterior cruciate ligament rehabilitation programs for physical active individuals. , 2000, Physical therapy.

[143]  F. J. Clark,et al.  Signaling of kinesthetic information by peripheral sensory receptors. , 1982, Annual review of neuroscience.

[144]  R. Schmidt,et al.  Fiber size distribution of myelinated and unmyelinated axons in the medial and posterior articular nerves of the cat's knee joint. , 1988, Somatosensory research.

[145]  K. Markolf,et al.  Stiffness and laxity of the knee--the contributions of the supporting structures. A quantitative in vitro study. , 1976, The Journal of bone and joint surgery. American volume.

[146]  J C Houk,et al.  Regulation of stiffness by skeletomotor reflexes. , 1979, Annual review of physiology.

[147]  L. Micheli,et al.  Mechanoreceptors in human cruciate ligaments. A histological study. , 1984, The Journal of bone and joint surgery. American volume.

[148]  E. Gómez-Barrena,et al.  Neural and muscular electric activity in the cat's knee. Changes when the anterior cruciate ligament is transected. , 1997, Acta orthopaedica Scandinavica.

[149]  D. McCloskey,et al.  The role of joint receptors in human kinaesthesia when intramuscular receptors cannot contribute. , 1987, The Journal of physiology.

[150]  F. Noyes,et al.  Ligamentous restraints to anterior-posterior drawer in the human knee. A biomechanical study. , 1980, The Journal of bone and joint surgery. American volume.

[151]  R J Johnson,et al.  The role of the musculature in injuries to the medial collateral ligament. , 1979, The Journal of bone and joint surgery. American volume.

[152]  S M Lephart,et al.  Reactive muscle firing of anterior cruciate ligament-injured females during functional activities. , 1999, Journal of athletic training.

[153]  Thomas Sinkjær,et al.  Muscle, reflex and central components in the control of the ankle joint in healthy and spastic man. , 1997 .

[154]  L. Draganich,et al.  An in vitro study of anterior cruciate ligament strain induced by quadriceps and hamstrings forces , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[155]  P. A. Hageman,et al.  Age and gender effects on postural control measures. , 1995, Archives of physical medicine and rehabilitation.

[156]  Douglas G. Stuart,et al.  Ensemble characterivstics ofcat locovmotionand its neural control , 1976, Progress in Neurobiology.

[157]  L. Kempe Handbook of Physiology. Section I. The Nervous System , 1982 .

[158]  S M Lephart,et al.  The Effects of Joint Position and Direction of Joint Motion on Proprioceptive Sensibility in Anterior Cruciate Ligament-Deficient Athletes , 1997, The American journal of sports medicine.

[159]  Matthews Pb Recent advances in the understanding of the muscle spindle. , 1971, The Scientific basis of medicine annual reviews.

[160]  S L Woo,et al.  The effects of knee motion and external loading on the length of the anterior cruciate ligament (ACL): a kinematic study. , 1991, Journal of biomechanical engineering.

[161]  J. L. Marshall,et al.  The supporting structures and layers on the medial side of the knee: an anatomical analysis. , 1979, The Journal of bone and joint surgery. American volume.

[162]  F. Bloom Principles of Neural Science, 3rd ed , 1993 .

[163]  E. Dabezies,et al.  Mechanoreceptors in the human anterior cruciate ligament , 1986, The Anatomical record.

[164]  P. Walker,et al.  Stabilizing mechanisms of the loaded and unloaded knee joint. , 1976, The Journal of bone and joint surgery. American volume.

[165]  K. Browne,et al.  The sensation of passive movement at the metatarso‐phalangeal joint of the great toe in man , 1954 .

[166]  K. Markolf,et al.  In vivo knee stability. A quantitative assessment using an instrumented clinical testing apparatus. , 1978, The Journal of bone and joint surgery. American volume.

[167]  B. Beynnon,et al.  Joint position sense is not changed after acute disruption of the anterior cruciate ligament. , 1999, Acta orthopaedica Scandinavica.

[168]  C F Ettlinger,et al.  A Method to Help Reduce the Risk of Serious Knee Sprains Incurred in Alpine Skiing , 1995, The American journal of sports medicine.

[169]  F. Fuss Anatomy of the cruciate ligaments and their function in extension and flexion of the human knee joint. , 1989, The American journal of anatomy.

[170]  H. Johansson,et al.  A sensory role for the cruciate ligaments. , 1991, Clinical orthopaedics and related research.

[171]  A. K. Aune,et al.  Hamstrings and gastrocnemius co‐contraction protects the anterior cruciate ligament against failure: An in vivo study in the rat , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.