Filter for biomedical imaging and image processing.

Image filtering techniques have numerous potential applications in biomedical imaging and image processing. The design of filters largely depends on the a priori, knowledge about the type of noise corrupting the image. This makes the standard filters application specific. Widely used filters such as average, Gaussian, and Wiener reduce noisy artifacts by smoothing. However, this operation normally results in smoothing of the edges as well. On the other hand, sharpening filters enhance the high-frequency details, making the image nonsmooth. An integrated general approach to design a finite impulse response filter based on Hebbian learning is proposed for optimal image filtering. This algorithm exploits the interpixel correlation by updating the filter coefficients using Hebbian learning. The algorithm is made iterative for achieving efficient learning from the neighborhood pixels. This algorithm performs optimal smoothing of the noisy image by preserving high-frequency as well as low-frequency features. Evaluation results show that the proposed finite impulse response filter is robust under various noise distributions such as Gaussian noise, salt-and-pepper noise, and speckle noise. Furthermore, the proposed approach does not require any a priori knowledge about the type of noise. The number of unknown parameters is few, and most of these parameters are adaptively obtained from the processed image. The proposed filter is successfully applied for image reconstruction in a positron emission tomography imaging modality. The images reconstructed by the proposed algorithm are found to be superior in quality compared with those reconstructed by existing PET image reconstruction methodologies.

[1]  Kannan Ramchandran,et al.  Low-complexity image denoising based on statistical modeling of wavelet coefficients , 1999, IEEE Signal Processing Letters.

[2]  Lei Zhang,et al.  Noise Reduction for Magnetic Resonance Images via Adaptive Multiscale Products Thresholding , 2003, IEEE Trans. Medical Imaging.

[3]  Pekka Hänninen,et al.  Two-photon excitation 4Pi confocal microscope: enhanced axial resolution microscope for biological research , 1995 .

[4]  Jos B. T. M. Roerdink,et al.  Denoising functional MR images: a comparison of wavelet denoising and Gaussian smoothing , 2004, IEEE Transactions on Medical Imaging.

[5]  H. Wu,et al.  Adaptive impulse detection using center-weighted median filters , 2001, IEEE Signal Processing Letters.

[6]  Michael I. Miller,et al.  The Use of Sieves to Stabilize Images Produced with the EM Algorithm for Emission Tomography , 1985, IEEE Transactions on Nuclear Science.

[7]  Meltem Izzetoglu,et al.  Motion artifact cancellation in NIR spectroscopy using Wiener filtering , 2005, IEEE Transactions on Biomedical Engineering.

[8]  Jerry L. Prince,et al.  A vector Wiener filter for dual-radionuclide imaging , 1996, IEEE Trans. Medical Imaging.

[9]  Aleksandra Pizurica,et al.  A versatile wavelet domain noise filtration technique for medical imaging , 2003, IEEE Transactions on Medical Imaging.

[10]  S. Marshall,et al.  New direct design method for weighted order statistic filters , 2004 .

[11]  Donald Geman,et al.  Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images , 1984, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[12]  N C Andreasen,et al.  Functional MRI statistical software packages: A comparative analysis , 1998, Human brain mapping.

[13]  Soo-Chang Pei,et al.  Recursive order-statistic soft morphological filters , 1998 .

[14]  Giovanni Ramponi,et al.  Fuzzy operator for sharpening of noisy images , 1992 .

[15]  M. Kazubek,et al.  Wavelet domain image denoising by thresholding and Wiener filtering , 2003, IEEE Signal Processing Letters.

[16]  Moncef Gabbouj,et al.  Center weighted median filters: Some properties and their applications in image processing , 1994, Signal Process..

[17]  H. M. Voort,et al.  Restoration of confocal images for quantitative image analysis , 1995 .

[18]  L. Shepp,et al.  A Statistical Model for Positron Emission Tomography , 1985 .

[19]  Benoit M. Dawant,et al.  Topological median filters , 2002, IEEE Trans. Image Process..

[20]  Martin Vetterli,et al.  Adaptive wavelet thresholding for image denoising and compression , 2000, IEEE Trans. Image Process..

[21]  Ernst H. K. Stelzer,et al.  Optical fluorescence microscopy in three dimensions: microtomoscopy , 1985 .

[22]  Zhenyu Zhou,et al.  Approximate maximum likelihood hyperparameter estimation for Gibbs priors , 1997, IEEE Trans. Image Process..

[23]  Jaakko Astola,et al.  Optimal weighted median filtering under structural constraints , 1995, IEEE Trans. Signal Process..

[24]  Richard M. Leahy,et al.  Statistic-based MAP image-reconstruction from Poisson data using Gibbs priors , 1992, IEEE Trans. Signal Process..

[25]  Partha P Mondal,et al.  Fuzzy-rule-based image reconstruction for positron emission tomography. , 2005, Journal of the Optical Society of America. A, Optics, image science, and vision.

[26]  P. Green Bayesian reconstructions from emission tomography data using a modified EM algorithm. , 1990, IEEE transactions on medical imaging.

[27]  K. Rajan,et al.  Neural network-based image reconstruction for positron emission tomography. , 2005, Applied optics.

[28]  Ulla Ruotsalainen,et al.  Using local median as the location of the prior distribution in iterative emission tomography image reconstruction , 1997 .

[29]  Ulla Ruotsalainen,et al.  Generalization of median root prior reconstruction , 2002, IEEE Transactions on Medical Imaging.

[30]  X. Xia,et al.  Image denoising using a local contextual hidden Markov model in the wavelet domain , 2001, IEEE Signal Process. Lett..