Neural networks approach to early breast cancer detection

Efficient prevention is strongly correlated with an early detection of breast cancer. The common effort of many researchers in this field resulted in the selection of the most prominent risk factors related to breast cancer. In this paper we present a neural network based model for the efficient automated identification of women at high risk of developing breast cancer from a wide, healthy population on the basis of data, referring to a properly selected set of risk factors and symptoms. Using this model we achieved a highly accurate classification and also the initial set of features reduction.

[1]  Antonio Camurri,et al.  HARP: a system for intelligent composer's assistance , 1991, Computer.

[2]  Bernard Widrow,et al.  Layered neural nets for pattern recognition , 1988, IEEE Trans. Acoust. Speech Signal Process..

[3]  Riccardo Poli,et al.  A neural network expert system for diagnosing and treating hypertension , 1991, Computer.

[4]  W. Willett,et al.  Breast cancer (1) , 1992, The New England journal of medicine.

[5]  J. Manson,et al.  Family history, age, and risk of breast cancer. Prospective data from the Nurses' Health Study. , 1993, JAMA.

[6]  Teuvo Kohonen,et al.  Self-Organization and Associative Memory , 1988 .

[7]  M. Skolnick,et al.  BRCA1 mutations in primary breast and ovarian carcinomas. , 1994, Science.

[8]  P. Wilding,et al.  Application of neural networks to the interpretation of laboratory data in cancer diagnosis. , 1992, Clinical chemistry.

[9]  P. Wingo,et al.  Cancer statistics, 1995 , 1995, CA: a cancer journal for clinicians.

[10]  M. Slattery,et al.  A comprehensive evaluation of family history and breast cancer risk. The Utah Population Database. , 1993, JAMA.

[11]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.

[12]  Steven E. Bayer,et al.  A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. , 1994, Science.

[13]  Geoffrey E. Hinton,et al.  Learning representations by back-propagating errors , 1986, Nature.

[14]  Keinosuke Fukunaga,et al.  Introduction to Statistical Pattern Recognition , 1972 .

[15]  W.V. Stoecker,et al.  Boundary detection in skin tumor images: An overall approach and a radial search algorithm , 1990, Pattern Recognit..

[16]  Christopher J. S. de Silva,et al.  Entropy maximization networks: an application to breast cancer prognosis , 1996, IEEE Trans. Neural Networks.

[17]  D. O. Hebb,et al.  The organization of behavior , 1988 .

[18]  Shun-ichi Amari,et al.  A Theory of Adaptive Pattern Classifiers , 1967, IEEE Trans. Electron. Comput..

[19]  Richard O. Duda,et al.  Pattern classification and scene analysis , 1974, A Wiley-Interscience publication.

[20]  Richard S. Sutton,et al.  Neuronlike adaptive elements that can solve difficult learning control problems , 1983, IEEE Transactions on Systems, Man, and Cybernetics.

[21]  Kumpati S. Narendra,et al.  Identification and control of dynamical systems using neural networks , 1990, IEEE Trans. Neural Networks.

[22]  R.P. Lippmann,et al.  Pattern classification using neural networks , 1989, IEEE Communications Magazine.

[23]  R. H. Moss,et al.  Neural network diagnosis of malignant melanoma from color images , 1994, IEEE Transactions on Biomedical Engineering.

[24]  J J Hopfield,et al.  Neural networks and physical systems with emergent collective computational abilities. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Jeffrey W. Hoffmeister,et al.  Using neural networks to select wavelet features for breast cancer diagnosis , 1996 .

[26]  N. E. Breslow Statistical Methods in Cancer Research , 1986 .

[27]  Richard P. Lippmann,et al.  An introduction to computing with neural nets , 1987 .

[28]  Ken-ichi Funahashi,et al.  On the approximate realization of continuous mappings by neural networks , 1989, Neural Networks.

[29]  D Brzakovic,et al.  An approach to automated detection of tumors in mammograms. , 1990, IEEE transactions on medical imaging.

[30]  A. Hodgkin,et al.  A quantitative description of membrane current and its application to conduction and excitation in nerve , 1952, The Journal of physiology.

[31]  A. Hodgkin,et al.  Action Potentials Recorded from Inside a Nerve Fibre , 1939, Nature.

[32]  J. Kelsey,et al.  Epidemiology of breast cancer. , 1990, Epidemiologic reviews.

[33]  S K Rogers,et al.  Artificial neural networks for early detection and diagnosis of cancer. , 1994, Cancer letters.