National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998-2008.

CONTEXT It is not known whether recent declines in ischemic heart disease and its risk factors have been accompanied by declines in heart failure (HF) hospitalization and mortality. OBJECTIVE To examine changes in HF hospitalization rate and 1-year mortality rate in the United States, nationally and by state or territory. DESIGN, SETTING, AND PARTICIPANTS From acute care hospitals in the United States and Puerto Rico, 55,097,390 fee-for-service Medicare beneficiaries hospitalized between 1998 and 2008 with a principal discharge diagnosis code for HF. MAIN OUTCOME MEASURES Changes in patient demographics and comorbidities, HF hospitalization rates, and 1-year mortality rates. RESULTS The HF hospitalization rate adjusted for age, sex, and race declined from 2845 per 100,000 person-years in 1998 to 2007 per 100,000 person-years in 2008 (P < .001), a relative decline of 29.5%. Age-adjusted HF hospitalization rates declined over the study period for all race-sex categories. Black men had the lowest rate of decline (4142 to 3201 per 100,000 person-years) among all race-sex categories, which persisted after adjusting for age (incidence rate ratio, 0.81; 95% CI, 0.79-0.84). Heart failure hospitalization rates declined significantly faster than the national mean in 16 states and significantly slower in 3 states. Risk-adjusted 1-year mortality decreased from 31.7% in 1999 to 29.6% in 2008 (P < .001), a relative decline of 6.6%. One-year mortality rates declined significantly in 4 states but increased in 5 states. CONCLUSIONS The overall HF hospitalization rate declined substantially from 1998 to 2008 but at a lower rate for black men. The overall 1-year mortality rate declined slightly over the past decade but remains high. Changes in HF hospitalization and 1-year mortality rates were uneven across states.

[1]  M. Cowie,et al.  Improving survival in the 6 months after diagnosis of heart failure in the past decade: population-based data from the UK , 2009, Heart.

[2]  Harlan M Krumholz,et al.  An Administrative Claims Model Suitable for Profiling Hospital Performance Based on 30-Day Mortality Rates Among Patients With Heart Failure , 2006, Circulation.

[3]  Harlan M Krumholz,et al.  Trends in comorbidity, disability, and polypharmacy in heart failure. , 2011, The American journal of medicine.

[4]  Daniel Levy,et al.  Long-term trends in the incidence of and survival with heart failure. , 2002, The New England journal of medicine.

[5]  B. Yawn,et al.  Incidence of heart failure after myocardial infarction: is it changing over time? , 2003, American journal of epidemiology.

[6]  D. Mozaffarian,et al.  Executive summary: heart disease and stroke statistics--2010 update: a report from the American Heart Association. , 2010, Circulation.

[7]  J. Zhang,et al.  What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. , 1998, JAMA.

[8]  S. Normand,et al.  Trends in length of stay and short-term outcomes among Medicare patients hospitalized for heart failure, 1993-2006. , 2010, JAMA.

[9]  K. Swedberg,et al.  Decreasing trends in the incidence of heart failure after acute myocardial infarction from 1993–2004: a study of 175 216 patients with a first acute myocardial infarction in Sweden , 2011, European journal of heart failure.

[10]  Colin Simpson,et al.  Long-Term Trends in First Hospitalization for Heart Failure and Subsequent Survival Between 1986 and 2003: A Population Study of 5.1 Million People , 2009, Circulation.

[11]  Alan S. Go,et al.  Population trends in the incidence and outcomes of acute myocardial infarction. , 2010, The New England journal of medicine.

[12]  Joseph Hung,et al.  Heart Failure: Incidence, Case Fatality, and Hospitalization Rates in Western Australia Between 1990 and 2005 , 2010, Circulation. Heart failure.

[13]  C. Yancy,et al.  Temporal trends in clinical characteristics, treatments, and outcomes for heart failure hospitalizations, 2002 to 2004: findings from Acute Decompensated Heart Failure National Registry (ADHERE). , 2007, American heart journal.

[14]  I. Hajjar,et al.  Hypertension: trends in prevalence, incidence, and control. , 2006, Annual review of public health.

[15]  D. Levy,et al.  The epidemiology of heart failure: the Framingham Study. , 1993, Journal of the American College of Cardiology.

[16]  B. Virnig,et al.  The Medicare-HMO revolving door--the healthy go in and the sick go out. , 1997, The New England journal of medicine.

[17]  P. Kaul,et al.  The epidemiology and management of elderly patients with myocardial infarction or heart failure , 2010, Heart Failure Reviews.

[18]  V. Roger,et al.  Risk factors for heart failure: a population-based case-control study. , 2009, The American journal of medicine.

[19]  B. Gage,et al.  Accuracy of ICD-9-CM Codes for Identifying Cardiovascular and Stroke Risk Factors , 2005, Medical care.

[20]  P. Austin,et al.  Trends in heart failure outcomes and pharmacotherapy: 1992 to 2000. , 2004, The American journal of medicine.

[21]  R. Vasan,et al.  Epidemiology of uncontrolled hypertension in the United States. , 2005, Circulation.

[22]  Ben Vandermeer,et al.  Cardiac resynchronization therapy for patients with left ventricular systolic dysfunction: a systematic review. , 2007, JAMA.

[23]  Mark V. Williams,et al.  Rehospitalizations among patients in the Medicare fee-for-service program. , 2009, The New England journal of medicine.

[24]  G. Fonarow,et al.  Improving Evidence-Based Care for Heart Failure in Outpatient Cardiology Practices: Primary Results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF) , 2010, Circulation.

[25]  D. Mozaffarian,et al.  Heart disease and stroke statistics--2010 update: a report from the American Heart Association. , 2010, Circulation.

[26]  K. Swedberg,et al.  Decreasing one-year mortality and hospitalization rates for heart failure in Sweden; Data from the Swedish Hospital Discharge Registry 1988 to 2000. , 2003, European Heart Journal.

[27]  B. Yawn,et al.  Trends in heart failure incidence and survival in a community-based population. , 2004, JAMA.

[28]  George A Mensah,et al.  Heart failure-related hospitalization in the U.S., 1979 to 2004. , 2008, Journal of the American College of Cardiology.

[29]  Sharon-Lise T. Normand,et al.  An Administrative Claims Measure Suitable for Profiling Hospital Performance on the Basis of 30-Day All-Cause Readmission Rates Among Patients With Heart Failure , 2008, Circulation. Cardiovascular quality and outcomes.

[30]  J. Cuzick,et al.  A Wilcoxon-type test for trend. , 1985, Statistics in medicine.

[31]  Marita G Titler,et al.  Cost of hospital care for older adults with heart failure: medical, pharmaceutical, and nursing costs. , 2008, Health services research.

[32]  Mark V. Williams,et al.  Rehospitalizations among patients in the Medicare fee-for-service program. , 2009, The New England journal of medicine.

[33]  P. Whelton,et al.  Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study. , 2001, Archives of internal medicine.

[34]  P. Heidenreich,et al.  Characteristics and Outcomes of Very Elderly Patients After First Hospitalization for Heart Failure , 2011, Circulation. Heart failure.

[35]  S. Normand,et al.  Recent Declines in Hospitalizations for Acute Myocardial Infarction for Medicare Fee-for-Service Beneficiaries: Progress and Continuing Challenges , 2010, Circulation.

[36]  T. Lumley,et al.  Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure. , 2004, American heart journal.

[37]  Hude Quan,et al.  Trends in heart failure care: has the incident diagnosis of heart failure shifted from the hospital to the emergency department and outpatient clinics? , 2011, European journal of heart failure.

[38]  A. Bonito,et al.  More Accurate Racial and Ethnic Codes for Medicare Administrative Data , 2008, Health care financing review.

[39]  W. Abraham Trends in Heart-Failure Incidence and Survival , 2004 .

[40]  J. Finn,et al.  Heart FailureCLINICAL PERSPECTIVE , 2010 .

[41]  Kevin J. Anstrom,et al.  Incidence and prevalence of heart failure in elderly persons, 1994-2003. , 2008, Archives of internal medicine.

[42]  R. Doughty,et al.  Understanding changing patterns of survival and hospitalization for heart failure over two decades in New Zealand: utility of ‘days alive and out of hospital’ from epidemiological data , 2010, European journal of heart failure.