Fluorescence spectroscopy: A technique with potential to improve the early detection of aerodigestive tract neoplasia

Any innovation which facilitates the early detection of neoplastic changes in upper aerodigestive tract mucosa has potential to greatly improve survival and quality of life in persons prone to develop malignancies in this area. One technology that has shown great promise during initial investigations is fluorescence spectroscopy. Fluorescence spectroscopy evaluates the physical and chemical properties of tissue by analyzing the intensity and character of light emitted in the form of fluorescence. This technology has been investigated for the noninvasive detection of malignancy in various sites including the gastrointestinal tract, lung, breast, and cervix.

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