Checkpoint-Independent Stabilization of Kinetochore-Microtubule Attachments by Mad2 in Human Cells
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[1] T. Holak,et al. Shugoshin is a Mad1/Cdc20‐like interactor of Mad2 , 2011, The EMBO journal.
[2] R. Benezra,et al. Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. , 2011, Cancer cell.
[3] R. Poon,et al. Orderly Inactivation of the Key Checkpoint Protein Mitotic Arrest Deficient 2 (MAD2) during Mitotic Progression* , 2011, The Journal of Biological Chemistry.
[4] S. Kondo,et al. Overexpression of MAD2 predicts clinical outcome in primary lung cancer patients. , 2011, Lung cancer.
[5] D. Compton,et al. Mechanisms of Chromosomal Instability , 2010, Current Biology.
[6] Nicholas D. Socci,et al. Mad2-induced chromosome instability leads to lung tumor relapse after oncogene withdrawal , 2010, Nature.
[7] E. Nigg,et al. Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1 , 2010, Journal of Cell Science.
[8] D. Compton,et al. Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability , 2009, Current Biology.
[9] R. Karess,et al. Separating the spindle, checkpoint, and timer functions of BubR1 , 2009, The Journal of cell biology.
[10] Samuel F. Bakhoum,et al. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics , 2008, Nature Cell Biology.
[11] T. Barraclough,et al. Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates , 2009 .
[12] H. Hashimoto,et al. Aberrant MAD2 expression in soft‐tissue sarcoma , 2008, Pathology international.
[13] E. Logarinho,et al. The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments. , 2008, Molecular biology of the cell.
[14] Duane A. Compton,et al. Examining the link between chromosomal instability and aneuploidy in human cells , 2008, The Journal of cell biology.
[15] R. Medema,et al. Mps1 Phosphorylates Borealin to Control Aurora B Activity and Chromosome Alignment , 2008, Cell.
[16] Andrea Musacchio,et al. The Mad2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint , 2007, Cell.
[17] E. Nigg,et al. Tension-sensitive Plk1 phosphorylation on BubR1 regulates the stability of kinetochore microtubule interactions. , 2007, Genes & development.
[18] E. Salmon,et al. The spindle-assembly checkpoint in space and time , 2007, Nature Reviews Molecular Cell Biology.
[19] S. Lowe,et al. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. , 2007, Cancer cell.
[20] M. Mapelli,et al. The Mad 2 Conformational Dimer : Structure and Implications for the Spindle Assembly Checkpoint , 2007 .
[21] D. Cimini,et al. Aurora Kinase Promotes Turnover of Kinetochore Microtubules to Reduce Chromosome Segregation Errors , 2006, Current Biology.
[22] P. Todd Stukenberg,et al. Two Complexes of Spindle Checkpoint Proteins Containing Cdc20 and Mad2 Assemble during Mitosis Independently of the Kinetochore in Saccharomyces cerevisiae , 2005, Eukaryotic Cell.
[23] P. Sorger,et al. A dual role for Bub1 in the spindle checkpoint and chromosome congression , 2005, The EMBO journal.
[24] T. Kapoor,et al. The human mitotic checkpoint protein BubR1 regulates chromosome–spindle attachments , 2005, Nature Cell Biology.
[25] W. Gerald,et al. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control , 2004, Nature.
[26] Elliot Botvinick,et al. Dynamics of Centromere and Kinetochore Proteins Implications for Checkpoint Signaling and Silencing , 2004, Current Biology.
[27] Viji M. Draviam,et al. Chromosome segregation and genomic stability. , 2004, Current opinion in genetics & development.
[28] A. Murray,et al. Spindle Checkpoint Component Mad2 Contributes to Biorientation of Homologous Chromosomes , 2003, Current Biology.
[29] Hao Li,et al. Mad2 and p53 expression profiles in colorectal cancer and its clinical significance. , 2003, World journal of gastroenterology.
[30] J. Peters,et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint , 2003, The Journal of cell biology.
[31] Stephen S. Taylor,et al. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores , 2003, The Journal of cell biology.
[32] D. Botstein,et al. Gene expression patterns in human liver cancers. , 2002, Molecular biology of the cell.
[33] Hongtao Yu,et al. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. , 2002, Molecular cell.
[34] Samantha G. Zeitlin,et al. CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis , 2001, The Journal of cell biology.
[35] G. Lucchini,et al. Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores , 2001, The EMBO journal.
[36] D. Botstein,et al. Diversity of gene expression in adenocarcinoma of the lung , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[37] G. Chan,et al. Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 , 2001, The Journal of cell biology.
[38] C. Miki,et al. Mitotic Checkpoint Protein hsMAD2 as a Marker Predicting Liver Metastasis of Human Gastric Cancers , 2001, Japanese journal of cancer research : Gann.
[39] Stephen S. Taylor,et al. Aneuploid colon cancer cells have a robust spindle checkpoint , 2001, EMBO reports.
[40] Alexey Khodjakov,et al. Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells , 2001, The Journal of cell biology.
[41] M. Kirschner,et al. Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20 , 2000, Nature Structural Biology.
[42] Ash A. Alizadeh,et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling , 2000, Nature.
[43] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[44] G. Borisy,et al. Kinetochore microtubule dynamics and the metaphase-anaphase transition , 1995, The Journal of cell biology.