High-Level Expression of the Smad Ubiquitin Ligase Smurf 2 Correlates with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma 1
暂无分享,去创建一个
H. Kuwano | H. Kato | T. Miyazaki | M. Nakajima | Y. Fukai | N. Masuda | K. Tsukada | M. Fukuchi | M. Sohda | Ryokuhei Manda
[1] H. Kuwano,et al. Decreased Smad4 expression in the transforming growth factor‐β signaling pathway during progression of esophageal squamous cell carcinoma , 2002, Cancer.
[2] C. Muro-Cacho,et al. Defective transforming growth factor beta signaling pathway in head and neck squamous cell carcinoma as evidenced by the lack of expression of activated Smad2. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[3] A. Atfi,et al. Mechanism for Mutational Inactivation of the Tumor Suppressor Smad2 , 2001, Molecular and Cellular Biology.
[4] R. Derynck,et al. Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[5] J. Wrana,et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. , 2000, Molecular cell.
[6] Xia Lin,et al. Smurf2 Is a Ubiquitin E3 Ligase Mediating Proteasome-dependent Degradation of Smad2 in Transforming Growth Factor-β Signaling* 210 , 2000, The Journal of Biological Chemistry.
[7] R. Derynck,et al. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15Ink4B transcription in response to TGF‐β , 2000 .
[8] H. Kuwano,et al. Mutation analysis of transforming growth factor beta type II receptor, Smad2, Smad3 and Smad4 in esophageal squamous cell carcinoma. , 2000, International journal of oncology.
[9] A. Ciechanover,et al. The ubiquitin system , 2000, Nature Medicine.
[10] J. Massagué,et al. Ubiquitin-dependent degradation of TGF-β-activated Smad2 , 1999, Nature Cell Biology.
[11] Jeffrey L. Wrana,et al. A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation , 1999, Nature.
[12] M. Hochstrasser,et al. Substrate Targeting in the Ubiquitin System , 1999, Cell.
[13] H. Saeki,et al. Proliferative activity of cancer cells in front and center areas of carcinoma in situ and invasive sites of esophageal squamous‐cell carcinoma , 1998, International journal of cancer.
[14] R. White,et al. Tumor Suppressing Pathways , 1998, Cell.
[15] Kohei Miyazono,et al. TGF-β signalling from cell membrane to nucleus through SMAD proteins , 1997, Nature.
[16] K. Kinzler,et al. Frequency of Smad gene mutations in human cancers. , 1997, Cancer research.
[17] Kohei Miyazono,et al. Positive and negative regulation of TGF-β signaling , 2000 .
[18] J. Massagué,et al. TGF- SIGNAL TRANSDUCTION , 1998 .
[19] S. Markowitz,et al. Tumor suppressor activity of the TGF-beta pathway in human cancers. , 1996, Cytokine & growth factor reviews.