Neuropathology of suicide: recent findings and future directions

[1]  M. Faghihi,et al.  Ketamine up-regulates a cluster of intronic miRNAs within the serotonin receptor 2C gene by inhibiting glycogen synthase kinase-3 , 2017, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[2]  J. Mann,et al.  Biomarkers of Suicide Attempt Behavior: Towards a Biological Model of Risk , 2017, Current Psychiatry Reports.

[3]  R. Jope,et al.  Up-regulation of insulin-like growth factor 2 by ketamine requires glycogen synthase kinase-3 inhibition , 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[4]  E. Sibille,et al.  Decrease in somatostatin‐positive cell density in the amygdala of females with major depression , 2017, Depression and anxiety.

[5]  J. Eriksson,et al.  Associations Between Self-Reported and Objectively Recorded Early Life Stress, FKBP5 Polymorphisms, and Depressive Symptoms in Midlife , 2016, Biological Psychiatry.

[6]  Randy F. Stout,et al.  Ketamine Inhibits ATP-Evoked Exocytotic Release of Brain-Derived Neurotrophic Factor from Vesicles in Cultured Rat Astrocytes , 2016, Molecular Neurobiology.

[7]  P. Courtet,et al.  Neuroinflammation in suicide: Toward a comprehensive model , 2016, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[8]  L. Pereira de Almeida,et al.  Gene therapy for the CNS using AAVs: The impact of systemic delivery by AAV9. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[9]  J. Savitz,et al.  Neuropathology of mood disorders: do we see the stigmata of inflammation? , 2016, Translational psychiatry.

[10]  D. Swaab,et al.  Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide. , 2016, Journal of psychiatric research.

[11]  O. Mors,et al.  Parental Psychiatric Disease and Risks of Attempted Suicide and Violent Criminal Offending in Offspring: A Population-Based Cohort Study. , 2016, JAMA psychiatry.

[12]  A. Juvekar,et al.  Agmatine ameliorates lipopolysaccharide induced depressive-like behaviour in mice by targeting the underlying inflammatory and oxido-nitrosative mediators , 2016, Pharmacology Biochemistry and Behavior.

[13]  D. Wasserman,et al.  Polygenic associations of neurodevelopmental genes in suicide attempt , 2016, Molecular Psychiatry.

[14]  T. Bredy,et al.  Evolving insights into RNA modifications and their functional diversity in the brain , 2016, Nature Neuroscience.

[15]  David Cohen,et al.  Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions , 2016, Front. Psychiatry.

[16]  D. Stellwagen,et al.  Bidirectional Homeostatic Regulation of a Depression-Related Brain State by Gamma-Aminobutyric Acidergic Deficits and Ketamine Treatment , 2016, Biological Psychiatry.

[17]  P. Xie,et al.  Serotonin-1A receptor alterations in depression: a meta-analysis of molecular imaging studies , 2016, BMC Psychiatry.

[18]  L. Skov,et al.  Risk of self‐harm and nonfatal suicide attempts, and completed suicide in patients with psoriasis: a population‐based cohort study , 2016, The British journal of dermatology.

[19]  Yonatan Stelzer,et al.  Editing DNA Methylation in the Mammalian Genome , 2016, Cell.

[20]  C. Farina,et al.  Astrocytes: Key Regulators of Neuroinflammation. , 2016, Trends in immunology.

[21]  R. Jope,et al.  Ketamine‐induced inhibition of glycogen synthase kinase‐3 contributes to the augmentation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid (AMPA) receptor signaling , 2016, Bipolar disorders.

[22]  O. Chiba-Falek,et al.  Gene Expression Analysis of Neurons and Astrocytes Isolated by Laser Capture Microdissection from Frozen Human Brain Tissues , 2016, Front. Mol. Neurosci..

[23]  Nicole R. Zürcher,et al.  Insights into neuroepigenetics through human histone deacetylase PET imaging , 2016, Science Translational Medicine.

[24]  L. Cavarec,et al.  Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression , 2016, Translational Psychiatry.

[25]  Y. Gao,et al.  The effects of cytosine methylation on general transcription factors , 2016, Scientific Reports.

[26]  L. Brundin,et al.  Role of Inflammation in Suicide: From Mechanisms to Treatment , 2016, Neuropsychopharmacology.

[27]  M. Vawter,et al.  Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission , 2016, Neuroscience & Biobehavioral Reviews.

[28]  M. Ronaghi,et al.  Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain , 2016, Science.

[29]  E. Brown,et al.  Rapid and Sustained Reductions in Current Suicidal Ideation Following Repeated Doses of Intravenous Ketamine: Secondary Analysis of an Open-Label Study. , 2016, The Journal of clinical psychiatry.

[30]  T. Bredy,et al.  Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice , 2016, The Journal of Neuroscience.

[31]  G. Rosoklija,et al.  Whole-transcriptome brain expression and exon-usage profiling in major depression and suicide: evidence for altered glial, endothelial and ATPase activity , 2016, Molecular Psychiatry.

[32]  Jens Hjerling-Leffler,et al.  Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system , 2016, Science.

[33]  A. Bani-Fatemi,et al.  GWAS analysis of suicide attempt in schizophrenia: Main genetic effect and interaction with early life trauma , 2016, Neuroscience Letters.

[34]  Gideon Rechavi,et al.  RNA modifications: what have we learned and where are we headed? , 2016, Nature Reviews Genetics.

[35]  Davide Cittaro,et al.  Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing , 2016, Cell.

[36]  J. Panksepp,et al.  Ultra-Low-Dose Buprenorphine as a Time-Limited Treatment for Severe Suicidal Ideation: A Randomized Controlled Trial. , 2016, The American journal of psychiatry.

[37]  L. Minuzzi,et al.  Exploring the Association between Serum BDNF and Attempted Suicide , 2016, Scientific Reports.

[38]  Xi-Ping Huang,et al.  NMDAR inhibition-independent antidepressant actions of ketamine metabolites , 2016, Nature.

[39]  G. Turecki,et al.  Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides , 2016, Molecular Psychiatry.

[40]  Gustavo Turecki,et al.  Suicide and suicidal behaviour , 2016, The Lancet.

[41]  Abraham Weizman,et al.  The CD44 ligand hyaluronic acid is elevated in the cerebrospinal fluid of suicide attempters and is associated with increased blood-brain barrier permeability. , 2016, Journal of affective disorders.

[42]  Vanja Tadić,et al.  Repurposing the CRISPR-Cas9 system for targeted DNA methylation , 2016, Nucleic acids research.

[43]  J. David Sweatt,et al.  Neural plasticity and behavior – sixty years of conceptual advances , 2016, Journal of neurochemistry.

[44]  E. Nestler Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction? , 2016, PLoS biology.

[45]  G. Rajkowska,et al.  Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder , 2016, Neuroscience.

[46]  Mikaela Behm,et al.  RNA Editing: A Contributor to Neuronal Dynamics in the Mammalian Brain. , 2016, Trends in genetics : TIG.

[47]  G. Rosoklija,et al.  A pilot integrative genomics study of GABA and glutamate neurotransmitter systems in suicide, suicidal behavior, and major depressive disorder , 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[48]  A. Caspi,et al.  Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort , 2016, PloS one.

[49]  M. Fava,et al.  Opioid Modulation With Buprenorphine/Samidorphan as Adjunctive Treatment for Inadequate Response to Antidepressants: A Randomized Double-Blind Placebo-Controlled Trial. , 2016, The American journal of psychiatry.

[50]  M. Meaney,et al.  Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review , 2016, Biological Psychiatry.

[51]  L. Minuzzi,et al.  Association between BDNF levels and suicidal behaviour: a systematic review and meta-analysis , 2015, Systematic Reviews.

[52]  J. Mattick,et al.  Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice , 2015, Biological Psychiatry.

[53]  J. Rinn,et al.  Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution , 2015, Neuron.

[54]  E. Koonin,et al.  Substantial DNA methylation differences between two major neuronal subtypes in human brain , 2015, Nucleic acids research.

[55]  G. Turecki,et al.  Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides , 2015, European Neuropsychopharmacology.

[56]  D. Rujescu,et al.  A genome‐wide association study of suicidal behavior , 2015, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[57]  G. Turecki,et al.  Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution , 2015, BMC Genomics.

[58]  Qi Xu,et al.  An association study of the m6A genes with major depressive disorder in Chinese Han population. , 2015, Journal of affective disorders.

[59]  R. Rajkumar,et al.  Ketamine and suicidal ideation in depression: Jumping the gun? , 2015, Pharmacological research.

[60]  J. Ecker,et al.  Non-CG Methylation in the Human Genome. , 2015, Annual review of genomics and human genetics.

[61]  N. Schork,et al.  Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach , 2015, Molecular Psychiatry.

[62]  Shiqing Ma,et al.  Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. , 2015, Nature chemical biology.

[63]  B. Bradley,et al.  Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder , 2015, Translational Psychiatry.

[64]  J. Kleinman,et al.  Sex differences in glutamate receptor gene expression in major depression and suicide , 2015, Molecular Psychiatry.

[65]  T. Haaf,et al.  Epigenetic Dysregulation in the Prefrontal Cortex of Suicide Completers , 2015, Cytogenetic and Genome Research.

[66]  Stuart J. Andrews,et al.  Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 (SAT1) gene in major depression and suicide , 2015, Neurobiology of Disease.

[67]  B. Miller,et al.  Meta-Analysis of Cytokines and Chemokines in Suicidality: Distinguishing Suicidal Versus Nonsuicidal Patients , 2015, Biological Psychiatry.

[68]  Terrence J. Sejnowski,et al.  Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain , 2015, Neuron.

[69]  J. Ecker,et al.  Exceptional epigenetics in the brain , 2015, Science.

[70]  G. Rajkowska,et al.  Oligodendrocyte morphometry and expression of myelin - Related mRNA in ventral prefrontal white matter in major depressive disorder. , 2015, Journal of psychiatric research.

[71]  Sarah A. Gagliano,et al.  A genome-wide association study of suicide severity scores in bipolar disorder. , 2015, Journal of psychiatric research.

[72]  S. Šviković,et al.  Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patients with major psychiatric disorders , 2015, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[73]  C. Blanco,et al.  Mental disorders and risk of suicide attempt: a national prospective study , 2015, Molecular Psychiatry.

[74]  K. Kaestner,et al.  TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts. , 2015, The Journal of clinical investigation.

[75]  J. Mann,et al.  DNA Methylation Perturbations in Genes Involved in Polyunsaturated Fatty Acid Biosynthesis Associated with Depression and Suicide Risk , 2015, Front. Neurol..

[76]  Wei Li,et al.  MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome , 2015, Proceedings of the National Academy of Sciences.

[77]  S. Brand,et al.  The relationship between lifetime suicide attempts, serum lipid levels, and metabolic syndrome in patients with bipolar disorders , 2015, International journal of psychiatry in clinical practice.

[78]  R. Hen,et al.  Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors , 2015, Neuropsychopharmacology.

[79]  L. Minthon,et al.  Low IL‐8 is associated with anxiety in suicidal patients: genetic variation and decreased protein levels , 2015, Acta psychiatrica Scandinavica.

[80]  B. Misiak,et al.  Higher total cholesterol level is associated with suicidal ideation in first-episode schizophrenia females , 2015, Psychiatry Research.

[81]  S. Linnarsson,et al.  Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq , 2015, Science.

[82]  Harrison W. Gabel,et al.  Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2 , 2015, Proceedings of the National Academy of Sciences.

[83]  Harrison W. Gabel,et al.  Disruption of DNA methylation-dependent long gene repression in Rett syndrome , 2015, Nature.

[84]  Miao Yu,et al.  Bacterial infection remodels the DNA methylation landscape of human dendritic cells , 2015, bioRxiv.

[85]  A. Rodrigues,et al.  Agmatine enhances antidepressant potency of MK-801 and conventional antidepressants in mice , 2015, Pharmacology Biochemistry and Behavior.

[86]  B. Birmaher,et al.  Familial pathways to early-onset suicide attempt: a 5.6-year prospective study. , 2015, JAMA psychiatry.

[87]  H. Nicolini,et al.  The role of brain‐derived neurotrophic factor (BDNF) Val66Met genetic polymorphism in bipolar disorder: a case–control study, comorbidities, and meta‐analysis of 16,786 subjects , 2015, Bipolar disorders.

[88]  G. Turecki,et al.  MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression , 2015, Translational Psychiatry.

[89]  R. Parsey,et al.  Positron emission tomography quantification of serotonin(1A) receptor binding in suicide attempters with major depressive disorder. , 2015, JAMA psychiatry.

[90]  C. Lim,et al.  A role for inflammatory metabolites as modulators of the glutamate N-methyl-d-aspartate receptor in depression and suicidality , 2015, Brain, Behavior, and Immunity.

[91]  Olivia J. Kirtley,et al.  The role of endogenous opioids in non-suicidal self-injurious behavior: Methodological challenges , 2015, Neuroscience & Biobehavioral Reviews.

[92]  K. Tye,et al.  From circuits to behaviour in the amygdala , 2015, Nature.

[93]  D. Levey,et al.  Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions , 2015, Molecular Psychiatry.

[94]  Christine DeLorenzo,et al.  Quantification of the Serotonin 1A Receptor Using PET: Identification of a Potential Biomarker of Major Depression in Males , 2015, Neuropsychopharmacology.

[95]  Maria da Graça Cantarelli,et al.  Potential neurochemical links between cholesterol and suicidal behavior , 2014, Psychiatry Research.

[96]  S. Balasubramanian,et al.  5-Hydroxymethylcytosine is a predominantly stable DNA modification. , 2014, Nature chemistry.

[97]  E. Baca-García,et al.  Toward a biosignature for suicide. , 2014, The American journal of psychiatry.

[98]  Yiyun Huang,et al.  Association of in vivo κ-opioid receptor availability and the transdiagnostic dimensional expression of trauma-related psychopathology. , 2014, JAMA psychiatry.

[99]  G. Turecki,et al.  Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides , 2014, Brain, Behavior, and Immunity.

[100]  A. Jackowski,et al.  Early life adversity, genomic plasticity, and psychopathology. , 2014, The lancet. Psychiatry.

[101]  W. Eaton,et al.  Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors. , 2014, The American journal of psychiatry.

[102]  M. Hiasa,et al.  Identification of a mammalian vesicular polyamine transporter , 2014, Scientific Reports.

[103]  G. Turecki The molecular bases of the suicidal brain , 2014, Nature Reviews Neuroscience.

[104]  E. Nestler,et al.  Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors , 2014, Nature Neuroscience.

[105]  G. Turecki,et al.  Elevated gene expression of glutamate receptors in noradrenergic neurons from the locus coeruleus in major depression. , 2014, The international journal of neuropsychopharmacology.

[106]  D. Wasserman,et al.  An overview of the neurobiology of suicidal behaviors as one meta-system , 2014, Molecular Psychiatry.

[107]  G. Rosoklija,et al.  Microglia of Prefrontal White Matter in Suicide , 2014, Journal of neuropathology and experimental neurology.

[108]  E. Isometsä,et al.  Differences in incidence of suicide attempts between bipolar I and II disorders and major depressive disorder , 2014, Bipolar disorders.

[109]  Maxwell R. Mumbach,et al.  Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA , 2014, Cell.

[110]  R. Lam,et al.  A systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials of ketamine in the rapid treatment of major depressive episodes , 2014, Psychological Medicine.

[111]  M. Rietschel,et al.  Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study , 2014, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[112]  Claire L. Lill,et al.  Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain , 2014, Neurobiology of Aging.

[113]  M. Nock,et al.  The psychology of suicidal behaviour. , 2014, The lancet. Psychiatry.

[114]  J. Mann,et al.  The neurobiology of suicide. , 2014, The lancet. Psychiatry.

[115]  G. Turecki,et al.  Functional DNA methylation in a transcript specific 3′UTR region of TrkB associates with suicide , 2014, Epigenetics.

[116]  L. Siever,et al.  A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide. , 2014, Human molecular genetics.

[117]  T. Bredy,et al.  Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation , 2014, Proceedings of the National Academy of Sciences.

[118]  J. Hooker,et al.  Visualizing epigenetics: Current advances and advantages in HDAC PET imaging techniques , 2014, Neuroscience.

[119]  G. Turecki,et al.  DNA methylation and childhood maltreatment: From animal models to human studies , 2014, Neuroscience.

[120]  E. Baca-García,et al.  Increased severity of suicidal behavior in impulsive aggressive patients exposed to familial adversities , 2014, Psychological Medicine.

[121]  M. Szyf,et al.  Astrocytic abnormalities and global DNA methylation patterns in depression and suicide , 2014, Molecular Psychiatry.

[122]  Andiara E. Freitas,et al.  Depressive-like behavior induced by tumor necrosis factor-α is abolished by agmatine administration , 2014, Behavioural Brain Research.

[123]  J. O. Roaldset,et al.  Triglycerides as a biological marker of repeated re-hospitalization resulting from deliberate self-harm in acute psychiatry patients: a prospective observational study , 2014, BMC Psychiatry.

[124]  J. Hauser,et al.  Possible association between haplotypes of the FKBP5 gene and suicidal bipolar disorder, but not with melancholic depression and psychotic features, in the course of bipolar disorder , 2014, Neuropsychiatric disease and treatment.

[125]  Guoping Fan,et al.  Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain , 2013, Nature Neuroscience.

[126]  M. Hiller,et al.  Transcriptome sequencing during mouse brain development identifies long non‐coding RNAs functionally involved in neurogenic commitment , 2013, The EMBO journal.

[127]  I. Craig,et al.  The protective effect of the obesity-associated rs9939609 A variant in fat mass- and obesity-associated gene on depression , 2013, Molecular Psychiatry.

[128]  M. Pompili,et al.  The role of inflammatory cytokines in suicidal behavior: A systematic review , 2013, European Neuropsychopharmacology.

[129]  G. Rosoklija,et al.  A pilot genome wide association and gene expression array study of suicide with and without major depression , 2013, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[130]  Yogesh Kumar Dwivedi,et al.  The Involvement of MicroRNAs in Major Depression, Suicidal Behavior, and Related Disorders: A Focus on miR-185 and miR-491-3p , 2013, Cellular and Molecular Neurobiology.

[131]  Sung-Wan Kim,et al.  BDNF promoter methylation and suicidal behavior in depressive patients. , 2013, Journal of affective disorders.

[132]  G. Turecki,et al.  Suicide and the polyamine system. , 2013, CNS & neurological disorders drug targets.

[133]  George M Church,et al.  Deciphering the functions and regulation of brain-enriched A-to-I RNA editing , 2013, Nature Neuroscience.

[134]  M. Mihanović,et al.  Brain-derived neurotrophic factor as a suicide factor in mental disorders , 2013, Acta Neuropsychiatrica.

[135]  D. Rujescu,et al.  Serotonergic genes and suicide: A systematic review , 2013, European Neuropsychopharmacology.

[136]  N. Volkow,et al.  Pain and suicidality: Insights from reward and addiction neuroscience , 2013, Progress in Neurobiology.

[137]  B. Czéh,et al.  Altered glial plasticity in animal models for mood disorders. , 2013, Current drug targets.

[138]  E. Gordon,et al.  Widespread reductions in gray matter volume in depression☆ , 2013, NeuroImage: Clinical.

[139]  E. Verona,et al.  Childhood emotional environment and self-injurious behaviors: the moderating role of the BDNF Val66Met polymorphism. , 2013, Journal of affective disorders.

[140]  N. Schork,et al.  Discovery and validation of blood biomarkers for suicidality , 2013, Molecular Psychiatry.

[141]  J. John Mann,et al.  Positron Emission Tomography Quantification of Serotonin Transporter in Suicide Attempters with Major Depressive Disorder , 2013, Biological Psychiatry.

[142]  Scott J. Russo,et al.  The brain reward circuitry in mood disorders , 2013, Nature Reviews Neuroscience.

[143]  Matthew D. Schultz,et al.  Global Epigenomic Reconfiguration During Mammalian Brain Development , 2013, Science.

[144]  M. M. Aglawe,et al.  Evidences for the agmatine involvement in antidepressant like effect of bupropion in mouse forced swim test , 2013, Pharmacology Biochemistry and Behavior.

[145]  B. Birmaher,et al.  Early childhood sexual abuse increases suicidal intent , 2013, World psychiatry : official journal of the World Psychiatric Association.

[146]  Gustavo Turecki,et al.  Gene expression deficits in pontine locus coeruleus astrocytes in men with major depressive disorder. , 2013, Journal of psychiatry & neuroscience : JPN.

[147]  P. Lutz Multiple serotonergic paths to antidepressant efficacy. , 2013, Journal of neurophysiology.

[148]  M. Szyf,et al.  Genome-wide methylation changes in the brains of suicide completers. , 2013, The American journal of psychiatry.

[149]  M. Boldrini,et al.  Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression , 2013, Neuropsychopharmacology.

[150]  J. Mann,et al.  The serotonergic system in mood disorders and suicidal behaviour , 2013, Philosophical Transactions of the Royal Society B: Biological Sciences.

[151]  J. Flegr How and why Toxoplasma makes us crazy. , 2013, Trends in parasitology.

[152]  G. Turecki,et al.  Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide. , 2013, Journal of psychiatric research.

[153]  Matthew K Nock,et al.  Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the National Comorbidity Survey Replication Adolescent Supplement. , 2013, JAMA psychiatry.

[154]  B. Kieffer,et al.  Opioid receptors: distinct roles in mood disorders , 2013, Trends in Neurosciences.

[155]  G. Turecki,et al.  Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide. , 2013, Journal of psychiatric research.

[156]  B. Shopsin The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study , 2013, Acta Neuropsychiatrica.

[157]  Xiaodong Cheng,et al.  High-resolution enzymatic mapping of genomic 5-hydroxymethylcytosine in mouse embryonic stem cells. , 2013, Cell reports.

[158]  J. Jui,et al.  Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. , 2013, Cell reports.

[159]  M. Barrachina,et al.  Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease , 2013, NeuroMolecular Medicine.

[160]  G. Turecki,et al.  Cholesterol and phospholipids in frontal cortex and synaptosomes of suicide completers: relationship with endosomal lipid trafficking genes. , 2013, Journal of psychiatric research.

[161]  A. Ghosh,et al.  Decreased mRNA and Protein Expression of BDNF, NGF, and their Receptors in the Hippocampus from Suicide: An Analysis in Human Postmortem Brain , 2013, Clinical medicine insights. Pathology.

[162]  N. Heintz,et al.  MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system , 2012, Epigenetics & Chromatin.

[163]  E. Baca-García,et al.  Suicidal phenotypes associated with family history of suicidal behavior and early traumatic experiences. , 2012, Journal of affective disorders.

[164]  S. Janelidze,et al.  Connecting inflammation with glutamate agonism in suicidality , 2012, Neuropsychopharmacology.

[165]  B. Bradley,et al.  Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions , 2012, Nature Neuroscience.

[166]  P. Mortensen,et al.  Toxoplasma gondii infection and self-directed violence in mothers. , 2012, Archives of general psychiatry.

[167]  M. Boldrini,et al.  Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression , 2012, Biological Psychiatry.

[168]  G. Corfas,et al.  A Critical Period for Social Experience–Dependent Oligodendrocyte Maturation and Myelination , 2012, Science.

[169]  G. Turecki,et al.  Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide. , 2012, The international journal of neuropsychopharmacology.

[170]  David G. Knowles,et al.  The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression , 2012, Genome research.

[171]  M. Åsberg,et al.  Low plasma vascular endothelial growth factor (VEGF) associated with completed suicide , 2012, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[172]  J. Doudna,et al.  A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity , 2012, Science.

[173]  Raymond K. Auerbach,et al.  An Integrated Encyclopedia of DNA Elements in the Human Genome , 2012, Nature.

[174]  P. Greengard,et al.  Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior , 2012, Proceedings of the National Academy of Sciences.

[175]  P. Barker,et al.  Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers , 2012, PloS one.

[176]  O. Elemento,et al.  Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons , 2012, Cell.

[177]  G. Hon,et al.  Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome , 2012, Cell.

[178]  Peter A. Jones Functions of DNA methylation: islands, start sites, gene bodies and beyond , 2012, Nature Reviews Genetics.

[179]  P. Greengard,et al.  Identification of the Cortical Neurons that Mediate Antidepressant Responses , 2012, Cell.

[180]  G. Ficz,et al.  Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution , 2012, Science.

[181]  N. Eisenberger The pain of social disconnection: examining the shared neural underpinnings of physical and social pain , 2012, Nature Reviews Neuroscience.

[182]  M. Cohen-Salmon,et al.  Deletion of Astroglial Connexins Weakens the Blood–Brain Barrier , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[183]  B. Wanner,et al.  Childhood trajectories of anxiousness and disruptiveness explain the association between early-life adversity and attempted suicide , 2012, Psychological Medicine.

[184]  Colm E. Nestor,et al.  Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. , 2012, Genome research.

[185]  F. Holsboer,et al.  Genome-Wide Association Study of Antidepressant Treatment-Emergent Suicidal Ideation , 2012, Neuropsychopharmacology.

[186]  G. Harrington,et al.  Fats and Factors: Lipid Profiles Associate with Personality Factors and Suicidal History in Bipolar Subjects , 2012, PloS one.

[187]  G. Turecki,et al.  Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides , 2011, Neuropsychopharmacology.

[188]  Peng Jin,et al.  5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging , 2011, Nature Neuroscience.

[189]  G. Turecki,et al.  Epigenetic regulation of spermidine/spermine N1-acetyltransferase (SAT1) in suicide. , 2011, Journal of psychiatric research.

[190]  M. Meaney,et al.  Dysfunction of Astrocyte Connexins 30 and 43 in Dorsal Lateral Prefrontal Cortex of Suicide Completers , 2011, Biological Psychiatry.

[191]  J. Mann,et al.  Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder , 2011, Brain, Behavior, and Immunity.

[192]  Takao K. Hensch,et al.  A critical period for auditory thalamocortical connectivity , 2011, Nature Neuroscience.

[193]  Bertram Müller-Myhsok,et al.  Genomewide Association Scan of Suicidal Thoughts and Behaviour in Major Depression , 2011, PloS one.

[194]  P. Lichtenstein,et al.  Familial clustering of suicide risk: a total population study of 11.4 million individuals , 2011, Psychological Medicine.

[195]  S. Nelson,et al.  Cell Type-Specific Transcriptomics in the Brain , 2011, The Journal of Neuroscience.

[196]  R. Hen,et al.  Antidepressants recruit new neurons to improve stress response regulation , 2011, Molecular Psychiatry.

[197]  M. Selbach,et al.  Global quantification of mammalian gene expression control , 2011, Nature.

[198]  Keji Zhao,et al.  Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. , 2011, Genes & development.

[199]  G. Turecki,et al.  The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression. , 2011, The international journal of neuropsychopharmacology.

[200]  A. Malafosse,et al.  Clinical and genetic correlates of suicidal ideation during antidepressant treatment in a depressed outpatient sample. , 2011, Pharmacogenomics.

[201]  Pamela B. Mahon,et al.  A genome-wide association study of attempted suicide , 2011, Molecular Psychiatry.

[202]  N. Pivac,et al.  The association between brain-derived neurotrophic factor polymorphism (BDNF Val66Met) and suicide. , 2011, Journal of affective disorders.

[203]  S. Janelidze,et al.  Cytokine levels in the blood may distinguish suicide attempters from depressed patients , 2011, Brain, Behavior, and Immunity.

[204]  O. Shirakawa,et al.  Association of FKBP5 gene haplotypes with completed suicide in the Japanese population , 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[205]  Per Svenningsson,et al.  Modulation of monoamine receptors by adaptor proteins and lipid rafts: role in some effects of centrally acting drugs and therapeutic agents. , 2011, Annual review of pharmacology and toxicology.

[206]  S. Cichon,et al.  Genome-wide association study of suicide attempts in mood disorder patients. , 2010, The American journal of psychiatry.

[207]  G. Dussor,et al.  Central modulation of pain. , 2010, The Journal of clinical investigation.

[208]  C. Nemeroff,et al.  Neurobiological and psychiatric consequences of child abuse and neglect. , 2010, Developmental psychobiology.

[209]  Mark Taylor,et al.  Suicide and schizophrenia: a systematic review of rates and risk factors , 2010, Journal of psychopharmacology.

[210]  M. Rietschel,et al.  Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project , 2010, The Pharmacogenomics Journal.

[211]  David R. Williams,et al.  Twelve-month prevalence of and risk factors for suicide attempts in the World Health Organization World Mental Health Surveys. , 2010, The Journal of clinical psychiatry.

[212]  M. Bianchin,et al.  The BDNF Val66Met polymorphism is an independent risk factor for high lethality in suicide attempts of depressed patients , 2010, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[213]  R. Tremblay,et al.  Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene–environment study , 2010, Molecular Psychiatry.

[214]  E. Isometsä,et al.  Incidence and predictors of suicide attempts in DSM-IV major depressive disorder: a five-year prospective study. , 2010, The American journal of psychiatry.

[215]  J. Mann,et al.  Non-suicidal self-injurious behavior, endogenous opioids and monoamine neurotransmitters. , 2010, Journal of affective disorders.

[216]  A. Nordström,et al.  Cholesterol, CSF 5-HIAA, violence and intent in suicidal men , 2010, Psychiatry Research.

[217]  N. Pedersen,et al.  Genetic influences on suicide and nonfatal suicidal behavior: Twin study findings , 2010, European Psychiatry.

[218]  K. Behar,et al.  Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole , 2010, Molecular Psychiatry.

[219]  Kelly C. Cukrowicz,et al.  The interpersonal theory of suicide. , 2010, Psychological review.

[220]  G. Turecki,et al.  Anterior cingulate pyramidal neurons display altered dendritic branching in depressed suicides. , 2010, Journal of psychiatric research.

[221]  A. Gratton,et al.  Evidence of Altered Polyamine Concentrations in Cerebral Cortex of Suicide Completers , 2010, Neuropsychopharmacology.

[222]  V. Carli,et al.  Increased BDNF promoter methylation in the Wernicke area of suicide subjects. , 2010, Archives of general psychiatry.

[223]  B. Devlin,et al.  Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study. , 2010, The American journal of psychiatry.

[224]  D. Goldman,et al.  Interaction of FKBP5, a Stress-Related Gene, with Childhood Trauma Increases the Risk for Attempting Suicide , 2010, Neuropsychopharmacology.

[225]  Yogesh K. Dwivedi Brain-derived neurotrophic factor and suicide pathogenesis , 2010, Annals of medicine.

[226]  H. Anisman,et al.  Altered Organization of GABAA Receptor mRNA Expression in the Depressed Suicide Brain , 2009, Front. Mol. Neurosci..

[227]  Sarah A. Zimmerman,et al.  Toxoplasma gondii Antibody Titers and History of Suicide Attempts in Patients With Recurrent Mood Disorders , 2009, The Journal of nervous and mental disease.

[228]  D. Rujescu,et al.  Profiling brain expression of the spermidine/spermine N1‐acetyltransferase 1 (SAT1) gene in suicide , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[229]  Gustavo Turecki,et al.  Familial aggregation of suicide explained by cluster B traits: a three-group family study of suicide controlling for major depressive disorder. , 2009, The American journal of psychiatry.

[230]  B. Taksande,et al.  Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine , 2009, Neuropharmacology.

[231]  G. Turecki,et al.  Histone methylation and decreased expression of TrkB.T1 in orbital frontal cortex of suicide completers , 2009, Molecular Psychiatry.

[232]  G. Turecki,et al.  Identification and Characterization of Spermidine/Spermine N1-Acetyltransferase Promoter Variants in Suicide Completers , 2009, Biological Psychiatry.

[233]  F. McMahon,et al.  Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients , 2009, Pharmacogenetics and genomics.

[234]  D. Charney,et al.  Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression , 2009, Biological Psychiatry.

[235]  Mark S Levenson,et al.  Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration , 2009, BMJ : British Medical Journal.

[236]  W. Bunney,et al.  Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression , 2009, PloS one.

[237]  David R. Williams,et al.  Cross-National Analysis of the Associations among Mental Disorders and Suicidal Behavior: Findings from the WHO World Mental Health Surveys , 2009, PLoS medicine.

[238]  Martin Samuelsson,et al.  Interleukin-6 Is Elevated in the Cerebrospinal Fluid of Suicide Attempters and Related to Symptom Severity , 2009, Biological Psychiatry.

[239]  M. Parent,et al.  Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers. , 2009, Journal of psychiatry & neuroscience : JPN.

[240]  J. John Mann,et al.  Antidepressants increase neural progenitor cells in the human hippocampus , 2009, Neuropsychopharmacology.

[241]  V. Carli,et al.  Brain derived neurotrophic factor (BDNF) genetic polymorphism (Val66Met) in suicide: A study of 512 cases , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[242]  N. Heintz,et al.  The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.

[243]  David R. Liu,et al.  Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1 , 2009, Science.

[244]  J. Sweatt,et al.  Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene , 2009, Biological Psychiatry.

[245]  J. Dietschy Central nervous system: cholesterol turnover, brain development and neurodegeneration , 2009, Biological chemistry.

[246]  Gustavo Turecki,et al.  Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse , 2009, Nature Neuroscience.

[247]  V. Willour,et al.  Family-based association of FKBP5 in bipolar disorder , 2009, Molecular Psychiatry.

[248]  A. Sequeira,et al.  Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression , 2009, Molecular Psychiatry.

[249]  A. Nordström,et al.  CSF 5-HIAA and DST non-suppression — Orthogonal biologic risk factors for suicide in male mood disorder inpatients , 2009, Psychiatry Research.

[250]  L. Siever,et al.  Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide , 2008, Molecular Psychiatry.

[251]  Miklós Palkovits,et al.  GABAA Receptor Promoter Hypermethylation in Suicide Brain: Implications for the Involvement of Epigenetic Processes , 2008, Biological Psychiatry.

[252]  H. Walter,et al.  Aberrant functional connectivity of dorsolateral prefrontal and cingulate networks in patients with major depression during working memory processing , 2008, Psychological Medicine.

[253]  Avram J. Holmes,et al.  Response conflict and frontocingulate dysfunction in unmedicated participants with major depression , 2008, Neuropsychologia.

[254]  L. Sher,et al.  The Role of Endogenous Opioids in the Pathophysiology of Self-Injurious and Suicidal Behavior , 2008, Archives of suicide research : official journal of the International Academy for Suicide Research.

[255]  R. Tremblay,et al.  Predicting suicide attempts in young adults with histories of childhood abuse , 2008, British Journal of Psychiatry.

[256]  A. Roy,et al.  Association of Polymorphism (Val66Met) of Brain-Derived Neurotrophic Factor with Suicide Attempts in Depressed Patients , 2008, Neuropsychobiology.

[257]  D. Ray,et al.  Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor , 2008, The Journal of endocrinology.

[258]  G. Turecki,et al.  The genetics of suicide: a critical review of molecular studies. , 2008, The Psychiatric clinics of North America.

[259]  M. Alda,et al.  Course of major depressive disorder and suicide outcome: a psychological autopsy study. , 2008, The Journal of clinical psychiatry.

[260]  D. Gerrelli,et al.  Neuronal function of Tbx20 conserved from nematodes to vertebrates. , 2008, Developmental biology.

[261]  M. Boldrini,et al.  Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides. , 2008, Journal of psychiatric research.

[262]  P. Cowen,et al.  Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression , 2008, British Journal of Psychiatry.

[263]  M. Leboyer,et al.  Interaction between BDNF Val66Met and childhood trauma on adult’s violent suicide attempt , 2008, Genes, brain, and behavior.

[264]  D. Rujescu,et al.  Elevated cytokine expression in the orbitofrontal cortex of victims of suicide , 2008, Acta psychiatrica Scandinavica.

[265]  G. Turecki,et al.  Implication of the polyamine system in mental disorders. , 2008, Journal of psychiatry & neuroscience : JPN.

[266]  S. Kennedy,et al.  Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder. , 2008, Bipolar disorders.

[267]  V. Arango,et al.  Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides , 2008, Molecular Psychiatry.

[268]  Mark A Frye,et al.  Increased Anterior Cingulate/Medial Prefrontal Cortical Glutamate and Creatine in Bipolar Depression , 2007, Neuropsychopharmacology.

[269]  D. Kupfer,et al.  Serotonin-1A receptor imaging in recurrent depression: replication and literature review. , 2007, Nuclear medicine and biology.

[270]  D. M. Lyons,et al.  Stress-induced changes in primate prefrontal profiles of gene expression , 2007, Molecular Psychiatry.

[271]  Abbas F. Sadikot,et al.  Serotonin4 (5-HT4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action , 2007, Neuron.

[272]  L. Stone,et al.  Potassium‐ and capsaicin‐induced release of agmatine from spinal nerve terminals , 2007, Journal of neurochemistry.

[273]  E. Levy,et al.  Fatty acid composition in postmortem brains of people who completed suicide. , 2007, Journal of psychiatry & neuroscience : JPN.

[274]  M. Fava,et al.  Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study. , 2007, Archives of general psychiatry.

[275]  R. Tremblay,et al.  Natural history of suicidal behaviors in a population-based sample of young adults , 2007, Psychological Medicine.

[276]  Sarah H Lisanby,et al.  Antidepressant-Induced Neurogenesis in the Hippocampus of Adult Nonhuman Primates , 2007, The Journal of Neuroscience.

[277]  J P Hatch,et al.  Fronto-limbic brain structures in suicidal and non-suicidal female patients with major depressive disorder , 2007, Molecular Psychiatry.

[278]  E. Levy,et al.  Cholesterol content in brains of suicide completers. , 2007, The international journal of neuropsychopharmacology.

[279]  C. Benkelfat,et al.  Patterns of gene expression in the limbic system of suicides with and without major depression , 2007, Molecular Psychiatry.

[280]  Punita Bhansali,et al.  Early Life Stress Alters Adult Serotonin 2C Receptor Pre-mRNA Editing and Expression of the α Subunit of the Heterotrimeric G-Protein Gq , 2007, The Journal of Neuroscience.

[281]  G. Rajkowska,et al.  GABAergic Neurons Immunoreactive for Calcium Binding Proteins are Reduced in the Prefrontal Cortex in Major Depression , 2007, Neuropsychopharmacology.

[282]  B. Bogerts,et al.  Dysregulation of GABAergic Neurotransmission in Mood Disorders , 2007, Annals of the New York Academy of Sciences.

[283]  Robert A Koeppe,et al.  Dysregulation of endogenous opioid emotion regulation circuitry in major depression in women. , 2006, Archives of general psychiatry.

[284]  Paul J Carlson,et al.  A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. , 2006, Archives of general psychiatry.

[285]  René Hen,et al.  Hippocampal Neurogenesis: Regulation by Stress and Antidepressants , 2006, Biological Psychiatry.

[286]  V. Arango,et al.  Neuronal Tryptophan Hydroxylase mRNA Expression in the Human Dorsal and Median Raphe Nuclei: Major Depression and Suicide , 2006, Neuropsychopharmacology.

[287]  Marc Flajolet,et al.  Alterations in 5-HT1B Receptor Function by p11 in Depression-Like States , 2006, Science.

[288]  James P. Herman,et al.  Limbic system mechanisms of stress regulation: Hypothalamo-pituitary-adrenocortical axis , 2005, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[289]  R. Myers,et al.  Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[290]  Nancy C Andreasen,et al.  Subgenual prefrontal cortex volumes in major depressive disorder and schizophrenia: diagnostic specificity and prognostic implications. , 2005, The American journal of psychiatry.

[291]  C. Brayne,et al.  Depression in the elderly: pathological study of raphe and locus ceruleus , 2005, Neuropathology and applied neurobiology.

[292]  G. Turecki,et al.  Familial aggregation of suicidal behavior: a family study of male suicide completers from the general population. , 2005, The American journal of psychiatry.

[293]  M. Boldrini,et al.  More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides , 2005, Brain Research.

[294]  H. Rytsälä,et al.  Prospective study of risk factors for attempted suicide among patients with DSM–IV major depressive disorder , 2005, British Journal of Psychiatry.

[295]  Andrew H. Miller,et al.  Cytokines and psychopathology: Lessons from interferon-α , 2004, Biological Psychiatry.

[296]  James C. Overholser,et al.  Cellular changes in the postmortem hippocampus in major depression , 2004, Biological Psychiatry.

[297]  M. Nowaczyk,et al.  Cholesterol metabolism and suicidality in Smith-Lemli-Opitz syndrome carriers. , 2004, The American journal of psychiatry.

[298]  B. Ravnkilde,et al.  Hippocampal volume and depression: a meta-analysis of MRI studies. , 2004, The American journal of psychiatry.

[299]  J. Mann,et al.  Familial transmission of mood disorders: convergence and divergence with transmission of suicidal behavior. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[300]  T. Matise,et al.  Widespread RNA editing of embedded alu elements in the human transcriptome. , 2004, Genome research.

[301]  I. Weaver,et al.  Epigenetic programming by maternal behavior , 2004, Nature Neuroscience.

[302]  P. Escribá,et al.  Increased mRNA Expression of α2A-Adrenoceptors, Serotonin Receptors and μ-Opioid Receptors in the Brains of Suicide Victims , 2004, Neuropsychopharmacology.

[303]  Eric Vermetten,et al.  Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. , 2004, The American journal of psychiatry.

[304]  N. Uranova,et al.  Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium , 2004, Schizophrenia Research.

[305]  J. Price,et al.  Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes , 2004, Biological Psychiatry.

[306]  David R Rosenberg,et al.  Reduced anterior cingulate cortex glutamatergic concentrations in childhood major depression. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[307]  R. Koeppe,et al.  Regulation of human affective responses by anterior cingulate and limbic mu-opioid neurotransmission. , 2003, Archives of general psychiatry.

[308]  Paul J. Harrison,et al.  The distribution and morphology of prefrontal cortex pyramidal neurons identified using anti-neurofilament antibodies SMI32, N200 and FNP7. Normative data and a comparison in subjects with schizophrenia, bipolar disorder or major depression. , 2003, Journal of psychiatric research.

[309]  Hoi-Chung Leung,et al.  Frontal activations associated with accessing and evaluating information in working memory: an fMRI study , 2003, NeuroImage.

[310]  G. Gilad,et al.  Overview of the Brain Polyamine-Stress-Response: Regulation, Development, and Modulation by Lithium and Role in Cell Survival , 2003, Cellular and Molecular Neurobiology.

[311]  Y. Hacımusalar,et al.  Neurobiology of suicidal behaviour , 2003, Nature Reviews Neuroscience.

[312]  Andrew H. Miller,et al.  When Not Enough Is Too Much: The Role of Insufficient Glucocorticoid Signaling in the Pathophysiology of Stress-Related Disorders , 2003 .

[313]  R. Hen,et al.  Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants , 2003, Science.

[314]  Yogesh K. Dwivedi,et al.  Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. , 2003, Archives of general psychiatry.

[315]  H. Kraemer,et al.  Untreated depression and hippocampal volume loss. , 2003, The American journal of psychiatry.

[316]  C. Schmauss Serotonin 2C Receptors: Suicide, Serotonin, and Runaway RNA Editing , 2003, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[317]  C. Benkelfat,et al.  A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior , 2003, Molecular Psychiatry.

[318]  A. Caspi,et al.  Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene , 2003, Science.

[319]  Robert Layfield,et al.  Oligodendrocytes Promote Neuronal Survival and Axonal Length by Distinct Intracellular Mechanisms: A Novel Role for Oligodendrocyte-Derived Glial Cell Line-Derived Neurotrophic Factor , 2003, The Journal of Neuroscience.

[320]  M. Åsberg,et al.  "Serotonin depression"--a biochemical subgroup within the affective disorders? , 2003, Science.

[321]  J. Price,et al.  Low glial numbers in the amygdala in major depressive disorder , 2002, Biological Psychiatry.

[322]  D. Reis,et al.  Evidence for endogenous agmatine in hypothalamo-neurohypophysial tract and its modulation on vasopressin release and Ca2+ channels , 2002, Brain Research.

[323]  C. Beasley,et al.  The density and spatial distribution of gabaergic neurons, labelled using calcium binding proteins, in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia , 2002, Biological Psychiatry.

[324]  K. Bucholz,et al.  A twin study of genetic and environmental influences on suicidality in men , 2002, Psychological Medicine.

[325]  Victoria Arango,et al.  Serotonin 1A Receptors, Serotonin Transporter Binding and Serotonin Transporter mRNA Expression in the Brainstem of Depressed Suicide Victims , 2001, Neuropsychopharmacology.

[326]  F. Holsboer,et al.  Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus , 2001, The European journal of neuroscience.

[327]  T. Pollmächer,et al.  Cytokine-associated emotional and cognitive disturbances in humans. , 2001, Archives of general psychiatry.

[328]  W. Drevets Neuroimaging studies of mood disorders , 2000, Biological Psychiatry.

[329]  A. Bird,et al.  Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[330]  E. Vartiainen,et al.  High serum cholesterol and risk of suicide. , 2000, The American journal of psychiatry.

[331]  J D Gabrieli,et al.  A resource model of the neural basis of executive working memory. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[332]  Bernadette Lipinski,et al.  Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study , 2000, Biological Psychiatry.

[333]  John H Krystal,et al.  Antidepressant effects of ketamine in depressed patients , 2000, Biological Psychiatry.

[334]  D. Fergusson,et al.  Risk factors and life processes associated with the onset of suicidal behaviour during adolescence and early adulthood , 2000, Psychological Medicine.

[335]  M. Meaney,et al.  Nongenomic transmission across generations of maternal behavior and stress responses in the rat. , 1999, Science.

[336]  J. Haycock,et al.  Elevated levels of tyrosine hydroxylase in the locus coeruleus in major depression , 1999, Biological Psychiatry.

[337]  B. Roth,et al.  Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗ ∗ See accompanying Editorial, in this issue. , 1999, Biological Psychiatry.

[338]  J. Price,et al.  Glial reduction in the subgenual prefrontal cortex in mood disorders. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[339]  L. Bierut,et al.  Suicidal behaviour: an epidemiological and genetic study , 1998, Psychological Medicine.

[340]  Yvette I. Sheline,et al.  Amygdala core nuclei volumes are decreased in recurrent major depression , 1998, Neuroreport.

[341]  J. Kleinman,et al.  Prodynorphin mRNA expression is increased in the patch vs matrix compartment of the caudate nucleus in suicide subjects , 1997, Molecular Psychiatry.

[342]  Shakti Sharma,et al.  Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. , 1997, Science.

[343]  D. Brent,et al.  Suicidal behavior runs in families. A controlled family study of adolescent suicide victims. , 1996, Archives of general psychiatry.

[344]  V. Arango,et al.  Fewer pigmented locus coeruleus neurons in suicide victims: Preliminary results , 1996, Biological Psychiatry.

[345]  J. García-Sevilla,et al.  Increased density of μ-opioid receptors in the postmortem brain of suicide victims , 1995, Brain Research.

[346]  E. Mościcki Gender differences in completed and attempted suicides. , 1994, Annals of epidemiology.

[347]  J. Haycock,et al.  Elevated Tyrosine Hydroxylase in the Locus Coeruleus of Suicide Victims , 1994, Journal of neurochemistry.

[348]  A. Biegon,et al.  Reduced tyrosine hydroxylase immunoreactivity in locus coeruleus of suicide victims , 1992, Synapse.

[349]  Anat Biegon,et al.  Regionally selective increases in μ opioid receptor density in the brains of suicide victims , 1990, Brain Research.

[350]  J. Egeland,et al.  Suicide and family loading for affective disorders. , 1985, JAMA.

[351]  J. Schildkraut,et al.  The catecholamine hypothesis of affective disorders: a review of supporting evidence. , 1965, The American journal of psychiatry.

[352]  E. D. Klonsky,et al.  Recent advances in differentiating suicide attempters from suicide ideators , 2017, Current opinion in psychiatry.

[353]  D. Rujescu,et al.  Combined Toxoplasma gondii seropositivity and high blood kynurenine--Linked with nonfatal suicidal self-directed violence in patients with schizophrenia. , 2016, Journal of psychiatric research.

[354]  Sung-Wan Kim,et al.  Associations between serum lipid levels and suicidal ideation among Korean older people. , 2016, Journal of affective disorders.

[355]  Patricia Langenberg,et al.  "Latent" infection with Toxoplasma gondii: association with trait aggression and impulsivity in healthy adults. , 2015, Journal of psychiatric research.

[356]  D. Steffens,et al.  Basolateral amygdala volume and cell numbers in major depressive disorder: a postmortem stereological study , 2014, Brain Structure and Function.

[357]  G. Turecki,et al.  Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers. , 2014, The international journal of neuropsychopharmacology.

[358]  Maiken Nedergaard,et al.  Heterogeneity of astrocytic form and function. , 2012, Methods in molecular biology.

[359]  Yogesh K. Dwivedi,et al.  Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims. , 2012, Journal of psychiatric research.

[360]  Y. Conwell,et al.  The relationships of attachment style and social maladjustment to death ideation in depressed women with a history of childhood sexual abuse. , 2012, Journal of clinical psychology.

[361]  D. Goldman,et al.  Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior. , 2012, Journal of psychiatric research.

[362]  V. Arango,et al.  Neuroanatomy of Serotonergic Abnormalities in Suicide , 2012 .

[363]  J. Dalmau,et al.  The emerging link between autoimmune disorders and neuropsychiatric disease. , 2011, The Journal of neuropsychiatry and clinical neurosciences.

[364]  A. Sequeira,et al.  Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers. , 2010, Journal of affective disorders.

[365]  M. Mintun,et al.  Antidepressant treatment normalizes hypoactivity in dorsolateral prefrontal cortex during emotional interference processing in major depression. , 2009, Journal of affective disorders.

[366]  B. Bogerts,et al.  Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide. , 2008, Journal of psychiatric research.

[367]  Andrew H. Miller,et al.  Cytokines sing the blues: inflammation and the pathogenesis of depression. , 2006, Trends in immunology.

[368]  Fuad G. Gwadry,et al.  Implication of SSAT by gene expression and genetic variation in suicide and major depression. , 2006, Archives of general psychiatry.

[369]  BMC Psychiatry BioMed Central , 2005 .

[370]  Arthur W Toga,et al.  Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex. , 2004, The American journal of psychiatry.

[371]  V. Arango,et al.  Serotonin brain circuits involved in major depression and suicide. , 2002, Progress in brain research.

[372]  Y. Hurd,et al.  Subjects with major depression or bipolar disorder show reduction of prodynorphin mRNA expression in discrete nuclei of the amygdaloid complex , 2002, Molecular Psychiatry.

[373]  B. Bogerts,et al.  Tyrosine hydroxylase immunoreactivity in the locus coeruleus is reduced in depressed non-suicidal patients but normal in depressed suicide patients , 1999, European Archives of Psychiatry and Clinical Neuroscience.

[374]  The FASEB Journal express article 10.1096/fj.00-0815fje. Published online June 27, 2001. Essential role for cholesterol in synaptic plasticity and neuronal degeneration , 2022 .