Peripherally inserted central venous catheters: alternative or first choice vascular access?

Background: Peripherally inserted central catheters (PICC) are intravenous devices inserted through a superficial or deep vein of an upper or lower extremity and advanced to the distal third of the superior vena cava or proximal third of the inferior vena cava. They offer the advantages of greater safety for infusion of vesicant/irritant and hyperosmolar solutions and enable administration of antibiotics, prolonged parenteral nutrition (PPN), and chemotherapy agents. They also involve reduced risk of infection compared to other vascular catheters and are more cost-effective than centrally inserted venous catheters (CICVC). Objectives: To present the results of our team’s experience with US-guided and fluoroscopy-positioned PICC placement at the Hospital and Maternidade São Luiz (HMSL) Itaim, Rede D’or, Brazil. Methods: This was a prospective, non-randomized study, conducted from February 2015 to November 2016. The institution’s preestablished protocol was followed when vascular access was requested. Indications, prevalent diseases, type of catheter implanted, technical success, and complications related to the catheters were analyzed and inclusion and exclusion criteria are described. Results: A total of 256 vascular accesses were requested, and 236 PICCs (92.1%) and 20 CICVCs (7.9%) were implanted. The main indications were as follows: prolonged antibiotic therapy (52%), PPN (19.3%), and difficult venous access (16%). Technical successes was achieved in 246 catheter placements (96.1%). The right basilic vein was the most common vein punctured for access, in 192 patients (75%), followed by the right brachial vein, in 28 patients (10.9%). Conclusions: Ultrasound-guided and fluoroscopy-positioned PICC placement had a low incidence of complications, reduced infection rates, and proved safe and effective in cases of difficult vascular access. PICCs can be considered the devices of choice for central vascular access.

[1]  S. Manjunath,et al.  “Peripherally Inserted Central Catheters: Our Experience from a Cancer Research Centre” , 2014, Indian Journal of Surgical Oncology.

[2]  V. Chopra,et al.  PICC-associated bloodstream infections: prevalence, patterns, and predictors. , 2014, The American journal of medicine.

[3]  Linping Song,et al.  Malposition of peripherally inserted central catheter: Experience from 3,012 patients with cancer , 2013, Experimental and therapeutic medicine.

[4]  M. Gorman,et al.  Central venous catheter care for the patient with cancer: American Society of Clinical Oncology clinical practice guideline. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[5]  R. Sinert,et al.  Systematic review: is real-time ultrasonic-guided central line placement by ED physicians more successful than the traditional landmark approach? , 2011, Emergency Medicine Journal.

[6]  C. Pui,et al.  Thrombolytic therapy for central venous catheter occlusion , 2012, Haematologica.

[7]  G. Moneta,et al.  Peripherally inserted central catheter usage patterns and associated symptomatic upper extremity venous thrombosis. , 2012, Journal of vascular surgery.

[8]  R. Dawson PICC Zone Insertion MethodTM (ZIMTM): A Systematic Approach to Determine the Ideal Insertion Site for PICCs in the Upper Arm , 2011 .

[9]  M. Wallace,et al.  Quality improvement guidelines for central venous access. , 1997, Journal of vascular and interventional radiology : JVIR.

[10]  G. Vaidean,et al.  Risk of venous thromboembolism in hospitalized patients with peripherally inserted central catheters. , 2009, Journal of hospital medicine.

[11]  L. Mazzolai,et al.  Randomized controlled trial of peripherally inserted central catheters vs. peripheral catheters for middle duration in‐hospital intravenous therapy , 2008, Journal of thrombosis and haemostasis : JTH.

[12]  A. Maraveyas,et al.  The Effectiveness of Nurse Led 2-D Ultrasound Guided Insertion of Peripherally Inserted Central Catheters in Adult Patients: A Systematic Review , 2008 .

[13]  L. Simcock No Going Back: Advantages of Ultrasound- Guided Upper Arm PICC Placement , 2008 .

[14]  R. Young,et al.  Efficacy of the CathRite system to guide bedside placement of peripherally inserted central venous catheters in critically ill patients: a pilot study. , 2007, Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.

[15]  S. Secoli,et al.  Complicações acerca do cateter venoso central de inserção periférica (PICC) , 2008 .

[16]  Marcus Ferrone,et al.  Risk of Catheter-Related Bloodstream Infection With Peripherally Inserted Central Venous Catheters Used in Hospitalized Patients , 2006 .

[17]  D. Links,et al.  Horner's syndrome after placement of a peripherally inserted central catheter. , 2006, JPEN. Journal of parenteral and enteral nutrition.

[18]  Dan M. Kluger,et al.  The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. , 2006, Mayo Clinic proceedings.

[19]  K. Kagisaki,et al.  Chylothorax as a complication of innominate vein thrombosis induced by a peripherally inserted central catheter , 2006, Anaesthesia.

[20]  K. Costeloe,et al.  The Cobweb Sign: Percutaneous Silastic Long Line Tip Placement in Tributaries of Superficial Veins , 2005, Journal of Perinatology.

[21]  Douglas F. Burns Clinical Investigation: Retrospective Analysis - The Vanderbilt PICC Service: Program, Procedural, and Patient Outcomes Successes , 2005 .

[22]  Dorthea D. McMahon Evaluating New Technology to Improve Patient Outcomes: A Quality Improvement Approach , 2002, Journal of infusion nursing : the official publication of the Infusion Nurses Society.

[23]  E. Steiger,et al.  Venous thrombosis associated with peripherally inserted central catheters: a retrospective analysis of the Cleveland Clinic experience. , 2002, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[24]  P. Santulli,et al.  Peripherally inserted central catheters with distal versus proximal valves: prospective randomized trial. , 2001, Journal of vascular and interventional radiology : JVIR.

[25]  F. Lynch,et al.  Venous thrombosis associated with the placement of peripherally inserted central catheters. , 2000, Journal of vascular and interventional radiology : JVIR.

[26]  P. Santulli,et al.  Prospective randomized comparison of valved versus nonvalved peripherally inserted central vein catheters. , 1999, AJR. American journal of roentgenology.