A study of facial expression in Parkinson's disease using a novel microcomputer-based method.

The aim of this study was to compare the smiling behaviour of a group of Parkinson's disease sufferers with a control group of a similar age using a novel microcomputer-based approach, which utilises a mathematical model of the face to quantify facial expression. The findings indicate that the Parkinson's group differed from the control group in the frequency of smiling while watching a series of cartoons and in the degree of mouth opening during smiling. Both groups completed the Levine-Pilowsky Depression questionnaire, and patients with Parkinson's disease had significantly higher depression scores than those of the control group. Significant negative correlations between depression score and frequency of smiling, and depression score and inner eyebrow separation were also found.

[1]  Vogel Hp Symptoms of Depression in Parkinson's Disease , 1982, Pharmacopsychiatria.

[2]  D M Boulton,et al.  The Classification of Depression by Numerical Taxonomy , 1969, British Journal of Psychiatry.

[3]  G. Klerman,et al.  Facial Electromyography in the Assessment of Improvement in Depression , 1978, Psychosomatic medicine.

[4]  H. Vogel Symptoms of Depression in Parkinson's Disease , 1982, Pharmacopsychiatria.

[5]  J. W. Warburton Depressive symptoms in Parkinson patients referred for thalamotomy. , 1967, Journal of neurology, neurosurgery, and psychiatry.

[6]  R. Mindham Psychiatric symptoms in Parkinsonism. , 1970, Journal of neurology, neurosurgery, and psychiatry.

[7]  M Thornton,et al.  Facial expressions can be modelled mathematically. , 1982, The British journal of psychiatry : the journal of mental science.

[8]  W. Rinn,et al.  The neuropsychology of facial expression: a review of the neurological and psychological mechanisms for producing facial expressions. , 1984, Psychological bulletin.

[9]  I Pilowsky,et al.  A microcomputer based approach to the quantification of facial expressions. , 1985, Australasian physical & engineering sciences in medicine.

[10]  I. Pilowsky,et al.  A Method for Measuring Depression: Validity Studies on a Depression Questionnaire , 1972, British Journal of Psychiatry.

[11]  R. Buck,et al.  Nonverbal Communication of Affect in Brain-Damaged Patients , 1980, Cortex.