Oxamides as novel NR2B selective NMDA receptor antagonists.

[1]  P. Chazot.  The NMDA receptor NR2B subunit: a valid therapeutic target for multiple CNS pathologies. , 2004, Current medicinal chemistry.

[2]  B. Ágai,et al.  Indole-2-carboxamides as novel NR2B selective NMDA receptor antagonists. , 2003, Bioorganic & medicinal chemistry letters.

[3]  B. Ágai,et al.  A facile synthesis of 3-(substituted benzyl)piperidines , 2003 .

[4]  S. Kolok,et al.  Inducible expression and pharmacology of recombinant NMDA receptors, composed of rat NR1a/NR2B subunits , 2003, Neurochemistry International.

[5]  L. Meltzer,et al.  NR2B selective NMDA receptor antagonists. , 2002, Current pharmaceutical design.

[6]  J. Hawkinson,et al.  4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist. , 1999, Journal of medicinal chemistry.

[7]  S. Boyce,et al.  Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn , 1999, Neuropharmacology.

[8]  F. Menniti,et al.  Antagonists selective for NMDA receptors containing the NR2B subunit. , 1999, Current pharmaceutical design.

[9]  J. Kemp,et al.  In Vitro Binding Properties in Rat Brain of [3H]Ro 25‐6981, a Potent and Selective Antagonist of NMDA Receptors Containing NR2B Subunits , 1998, Journal of neurochemistry.

[10]  J. Kemp,et al.  Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. , 1997, The Journal of pharmacology and experimental therapeutics.

[11]  A. Malmberg,et al.  Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. , 1997, The Journal of pharmacology and experimental therapeutics.

[12]  M. Collins,et al.  (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses. , 1995, Journal of medicinal chemistry.

[13]  S. Hunskaar,et al.  Formalin test in mice, a useful technique for evaluating mild analgesics , 1985, Journal of Neuroscience Methods.

[14]  A. Janowsky,et al.  The N-methyl-D-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications. , 2003, Pharmacology & therapeutics.

[15]  H. Mil,et al.  The influence of bumetanide on the membrane potential of mouse skeletal muscle cells in isotonic and hypertonic media. , 1997 .