Structural studies of the translational apparatus.

[1]  Anders Liljas,et al.  Structural aspects of protein synthesis , 2004, Nature Structural Biology.

[2]  J Frank,et al.  Structure and structural variations of the Escherichia coli 30 S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy. , 1999, Journal of molecular biology.

[3]  S. Harvey,et al.  Major groove binding of the tRNA/mRNA complex to the 16 S ribosomal RNA decoding site. , 1999, Journal of molecular biology.

[4]  A. Liljas,et al.  The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. , 1998, Structure.

[5]  J. Puglisi,et al.  Structural origins of gentamicin antibiotic action , 1998, The EMBO journal.

[6]  A. Tocilj,et al.  Crystallographic studies on the ribosome, a large macromolecular assembly exhibiting severe nonisomorphism, extreme beam sensitivity and no internal symmetry. , 1998, Acta crystallographica. Section A, Foundations of crystallography.

[7]  P. Moore,et al.  Structure and stability of variants of the sarcin-ricin loop of 28S rRNA: NMR studies of the prokaryotic SRL and a functional mutant. , 1998, RNA.

[8]  R. Gutell,et al.  A functional ribosomal RNA tertiary structure involves a base triple interaction. , 1998, Biochemistry.

[9]  D. Draper,et al.  The solution structure of ribosomal protein S4 Δ41 reveals two subdomains and a positively charged surface that may interact with RNA , 1998, EMBO Journal.

[10]  D. Draper,et al.  The crystal structure of ribosomal protein S4 reveals a two‐domain molecule with an extensive RNA‐binding surface: one domain shows structural homology to the ETS DNA‐binding motif , 1998, The EMBO journal.

[11]  J Frank,et al.  Escherichia coli 70 S ribosome at 15 A resolution by cryo-electron microscopy: localization of fMet-tRNAfMet and fitting of L1 protein. , 1998, Journal of molecular biology.

[12]  Joachim Frank,et al.  A 9 Å Resolution X-Ray Crystallographic Map of the Large Ribosomal Subunit , 1998, Cell.

[13]  J. Nyborg,et al.  Protein biosynthesis: structural studies of the elongation cycle , 1998, FEBS letters.

[14]  B. Golden,et al.  Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance. , 1998, Journal of molecular biology.

[15]  P. Moore,et al.  The structure of a methylated tetraloop in 16S ribosomal RNA. , 1998, Structure.

[16]  F. Zemlin,et al.  Correlation of the expansion segments in mammalian rRNA with the fine structure of the 80 S ribosome; a cryoelectron microscopic reconstruction of the rabbit reticulocyte ribosome at 21 A resolution. , 1998, Journal of molecular biology.

[17]  N. Leontis,et al.  Structure and dynamics of ribosomal RNA. , 1998, Current opinion in structural biology.

[18]  V. Ramakrishnan,et al.  Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome. , 1998, Trends in biochemical sciences.

[19]  J Frank,et al.  Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[20]  V. Ramakrishnan,et al.  Conformational variability of the N-terminal helix in the structure of ribosomal protein S15. , 1998, Structure.

[21]  J. Puglisi,et al.  Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16 S rRNA. , 1998, Journal of molecular biology.

[22]  J. Puglisi,et al.  Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA. , 1998, Journal of molecular biology.

[23]  M van Heel,et al.  The 80S rat liver ribosome at 25 A resolution by electron cryomicroscopy and angular reconstitution. , 1998, Structure.

[24]  R. Garrett,et al.  The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre. , 1998, Journal of molecular biology.

[25]  Harry F Noller,et al.  Molecular Movement inside the Translational Engine , 1998, Cell.

[26]  Harry F Noller,et al.  Mapping the Position of Translational Elongation Factor EF-G in the Ribosome by Directed Hydroxyl Radical Probing , 1998, Cell.

[27]  J Frank,et al.  Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. , 1997, Science.

[28]  P. Moore,et al.  The loop E-loop D region of Escherichia coli 5S rRNA: the solution structure reveals an unusual loop that may be important for binding ribosomal proteins. , 1997, Structure.

[29]  T. Steitz,et al.  Metals, Motifs, and Recognition in the Crystal Structure of a 5S rRNA Domain , 1997, Cell.

[30]  S. Grzesiek,et al.  The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA. , 1997, Journal of molecular biology.

[31]  H. Noller,et al.  Structure of a conserved RNA component of the peptidyl transferase centre , 1997, Nature Structural Biology.

[32]  R. Brimacombe,et al.  Visualization of elongation factor Tu on the Escherichia coli ribosome , 1997, Nature.

[33]  J Frank,et al.  The ribosome at higher resolution--the donut takes shape. , 1997, Current opinion in structural biology.

[34]  R. Brimacombe,et al.  Arrangement of tRNAs in Pre- and Posttranslocational Ribosomes Revealed by Electron Cryomicroscopy , 1997, Cell.

[35]  J. Puglisi,et al.  Structure of the A Site of Escherichia coli 16S Ribosomal RNA Complexed with an Aminoglycoside Antibiotic , 1996, Science.

[36]  J. Nyborg,et al.  Structure of the ternary complex of EF-Tu: macromolecular mimicry in translation. , 1996, Trends in biochemical sciences.

[37]  A. Liljas,et al.  Crystal structure of the RNA binding ribosomal protein L1 from Thermus thermophilus. , 1996, The EMBO journal.

[38]  F. Jurnak,et al.  A complex profile of protein elongation: translating chemical energy into molecular movement. , 1996, Structure.

[39]  J. Frank,et al.  Direct Visualization of A-, P-, and E-Site Transfer RNAs in the Escherichia coli Ribosome , 1996, Science.

[40]  S Thirup,et al.  Crystal Structure of the Ternary Complex of Phe-tRNAPhe, EF-Tu, and a GTP Analog , 1995, Science.

[41]  J. Frank,et al.  A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome , 1995, Nature.

[42]  R. Brimacombe,et al.  The structure of ribosomal RNA: a three-dimensional jigsaw puzzle. , 1995, European journal of biochemistry.

[43]  A. Liljas,et al.  Three‐dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus. , 1994, The EMBO journal.

[44]  J. Wang,et al.  The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. , 1994, The EMBO journal.

[45]  I. Wool,et al.  The conformation of the sarcin/ricin loop from 28S ribosomal RNA. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[46]  D. Draper,et al.  Recognition of the highly conserved GTPase center of 23 S ribosomal RNA by ribosomal protein L11 and the antibiotic thiostrepton. , 1991, Journal of molecular biology.

[47]  P. Sigler,et al.  The 3 A crystal structure of yeast initiator tRNA: functional implications in initiator/elongator discrimination. , 1991, The EMBO journal.

[48]  A Yonath,et al.  A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstruction. , 1987, Science.

[49]  J. Frank,et al.  The movement of tRNA through the ribosome. , 1998, Biophysical journal.

[50]  P. Moore,et al.  The three-dimensional structure of the ribosome and its components. , 1998, Annual review of biophysics and biomolecular structure.

[51]  J. Frank,et al.  Three-dimensional structure of the yeast ribosome. , 1998, Nucleic acids research.