Experimental epidural anaesthesia in the dog with lignocaine and bupivacaine.

Regional epidural anaesthesia was produced with lignocaine and bupivacaine in dogs with permanently implanted catheters in the lumbar epidural space. Neurological techniques were used to evaluate and measure the signs of anaesthesia. The response to both drugs in the dog paralleled the response in man, bupivacaine proving to be more potent than lignocaine, having less propensity to spread, and less of a sedative effect.