Rapid extended coverage simultaneous multisection black-blood vessel wall MR imaging.

A two-dimensional rapid extended coverage (REX) rapid acquisition with relaxation enhancement (RARE) pulse sequence for simultaneous multisection double inversion-recovery (DIR) black-blood vessel wall magnetic resonance (MR) imaging was developed. Aortic vessel wall MR imaging was performed in five healthy subjects (mean age, 33 years +/- 4 [SD]) and five patients with atherosclerotic disease (mean age, 67 years +/- 11.7). Shortening of blood inversion time and imaging of multiple sections after single DIR block resulted in simultaneous acquisition of up to 20 aortic wall sections in less than 1 minute (spatial resolution, 0.97 x 0.97 x 3 mm(3)). Higher signal-to-noise ratios per unit time per section (16.0 +/- 2.45 vs 7.5 +/- 1.10, P <.05), no significant changes in contrast-to-noise ratios (15.0 +/- 5.3 vs 20.1 +/- 3.9, P >.05), and 17-fold improvement in acquisition time compared with those at conventional single-section DIR RARE imaging was achieved. Use of the REX method significantly shortened aortic imaging acquisition times without degrading image quality.

[1]  Robin M Heidemann,et al.  Generalized autocalibrating partially parallel acquisitions (GRAPPA) , 2002, Magnetic resonance in medicine.

[2]  René M. Botnar,et al.  Noninvasive Coronary Vessel Wall and Plaque Imaging With Magnetic Resonance Imaging , 2000, Circulation.

[3]  D A Steinman,et al.  Effect of black blood MR image quality on vessel wall segmentation , 2001, Magnetic resonance in medicine.

[4]  V. Fuster,et al.  Effects of Lipid-Lowering by Simvastatin on Human Atherosclerotic Lesions: A Longitudinal Study by High-Resolution, Noninvasive Magnetic Resonance Imaging , 2001, Circulation.

[5]  Chun Yuan,et al.  T1‐insensitive flow suppression using quadruple inversion‐recovery , 2002, Magnetic resonance in medicine.

[6]  O. Simonetti,et al.  "Black blood" T2-weighted inversion-recovery MR imaging of the heart. , 1996, Radiology.

[7]  J. Weinberger.  Noninvasive imaging of atherosclerotic plaque in the arch of the aorta with transcutaneous B-mode ultrasonography. , 2002, Neuroimaging clinics of North America.

[8]  Bob S. Hu,et al.  Real‐time black‐blood MRI using spatial presaturation , 2001, Journal of magnetic resonance imaging : JMRI.

[9]  Dennis L Parker,et al.  Improved efficiency in double‐inversion fast spin‐echo imaging , 2002, Magnetic resonance in medicine.

[10]  C Yuan,et al.  Carotid atherosclerotic plaque: noninvasive MR characterization and identification of vulnerable lesions. , 2001, Radiology.

[11]  V. Fuster,et al.  In vivo magnetic resonance evaluation of atherosclerotic plaques in the human thoracic aorta: a comparison with transesophageal echocardiography. , 2000, Circulation.

[12]  René M. Botnar,et al.  3D coronary vessel wall imaging utilizing a local inversion technique with spiral image acquisition , 2001, Magnetic resonance in medicine.

[13]  V. Fuster,et al.  Clinical Imaging of the High-Risk or Vulnerable Atherosclerotic Plaque , 2001, Circulation research.

[14]  René M. Botnar,et al.  Three-Dimensional Black-Blood Cardiac Magnetic Resonance Coronary Vessel Wall Imaging Detects Positive Arterial Remodeling in Patients With Nonsignificant Coronary Artery Disease , 2002, Circulation.

[15]  J Coste,et al.  Comparison of single-shot fast spin-echo and conventional spin-echo sequences for MR imaging of the heart: initial experience. , 2001, Radiology.

[16]  Zahi A Fayad,et al.  Acute coronary syndromes: biology , 1999, The Lancet.

[17]  René M. Botnar,et al.  Age and Sex Distribution of Subclinical Aortic Atherosclerosis: A Magnetic Resonance Imaging Examination of the Framingham Heart Study , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[18]  Chun Yuan,et al.  Classification of Human Carotid Atherosclerotic Lesions With In Vivo Multicontrast Magnetic Resonance Imaging , 2002, Circulation.

[19]  Samin K. Sharma,et al.  Noninvasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging. , 2000, Circulation.

[20]  Hee Kwon Song,et al.  Multislice double inversion pulse sequence for efficient black‐blood MRI , 2002, Magnetic resonance in medicine.

[21]  Bob S. Hu,et al.  High‐resolution three‐dimensional in vivo imaging of atherosclerotic plaque , 1999, Magnetic resonance in medicine.

[22]  Peter Libby,et al.  Current Concepts of the Pathogenesis of the Acute Coronary Syndromes , 2001, Circulation.

[23]  G Johnson,et al.  Thoracic aorta: rapid black-blood MR imaging with half-Fourier rapid acquisition with relaxation enhancement with or without electrocardiographic triggering. , 1999, Radiology.