Old and new in exploring the anterior chamber angle.

Angle-closure glaucoma includes a number of entities with closed angle, elevated intraocular pressure, in association with optic nerve damage and visual field defects as common markers. These entities are characterized by irido-trabecular apposition, irido-trabecular synechiae or both. The angle configuration must be systematically checked at least one time in patients presenting with raised intraocular pressure or glaucoma. Gonioscopy represented for a long time the gold standard for clinically assessing anterior chamber angle structures and their configuration. However, the interpretation of gonio-scopic findings is subjective and only semiquantitative. With the development of new imaging techniques of the anterior segment, new analysis methods have also emerged. Ultrabiomicroscopy was the first method of analyzing the anterior segment and is still the only imaging technique for all anterior segment structures (especially the ciliary body). Another method is optical coherence tomography, a non-contact technique by which angle configuration can be assessed in a more rapid and less invasive manner. Recently developed Pentacam technology could represent in the near future a more quantitative, rapid and non-invasive screening tool which could allow early detection of angle closure glaucoma and narrow angle configurations by measuring a set of anterior chamber parameters. List of abbreviations: ACG -angle closure glaucoma, ASOCT-anterior segment optical coherence tomography UMB- ultrasound biomicroscopy (ultrabiomicroscopy), PAS-posterior angle synechiae ACD-anterior chamber depth, ACV-anterior chamber volume, PLI-periphery laser iridotomy.

[1]  F. Källmark,et al.  Evaluation of Nasal and Temporal Anterior Chamber Angle with Four Different Techniques , 2013 .

[2]  Aliş,et al.  Glaucoma anterior chamber morphometry based on optical Scheimpflug images , 2010 .

[3]  Mingguang He,et al.  Anterior chamber angle assessment techniques. , 2008, Survey of ophthalmology.

[4]  Ronald H Silverman,et al.  High‐resolution ultrasound imaging of the eye – a review , 2009, Clinical & experimental ophthalmology.

[5]  Paul J Foster,et al.  Detection of gonioscopically occludable angles and primary angle closure glaucoma by estimation of limbal chamber depth in Asians: modified grading scheme , 2000, The British journal of ophthalmology.

[6]  F. Abolbashari,et al.  Assessment of the anterior chamber parameters after laser iridotomy in primary angle close suspect using Pentacam and gonioscopy. , 2013, International journal of ophthalmology.

[7]  D. Friedman,et al.  Changes in anterior segment morphology in response to illumination and after laser iridotomy in Asian eyes: an anterior segment OCT study , 2007, British Journal of Ophthalmology.

[8]  F. Källmark,et al.  Difference in the anterior chamber angle of the four meridians , 2012 .

[9]  H Iijima,et al.  Ultrasound biomicroscopic study of ciliary body thickness in eyes with narrow angles. , 2000, American journal of ophthalmology.

[10]  Samin Hong,et al.  Anterior Chamber Measurements by Pentacam and AS-OCT in Eyes With Normal Open Angles , 2008, Korean journal of ophthalmology : KJO.

[11]  Mingguang He,et al.  Laser peripheral iridotomy in eyes with narrow drainage angles: ultrasound biomicroscopy outcomes. The Liwan Eye Study. , 2007, Ophthalmology.

[12]  D. Edgar,et al.  Noncontact Screening Methods for the Detection of Narrow Anterior Chamber Angles. , 2015, Investigative ophthalmology & visual science.

[13]  D. Friedman,et al.  Comparison of gonioscopy and anterior segment ocular coherence tomography in detecting angle closure in different quadrants of the anterior chamber angle. , 2008, Ophthalmology.

[14]  Y. Tano,et al.  [Clinical study of anterior ocular segment topography in angle-closure glaucoma using the three-dimensional anterior segment analyzer Pentacam]. , 2006, Nippon Ganka Gakkai zasshi.

[15]  M. Puech ophtalmologiques UBM and glaucoma : diagnosis and follow-up of plateau iris , 2013 .

[16]  D. Friedman,et al.  Detection of primary angle closure using anterior segment optical coherence tomography in Asian eyes. , 2007, Ophthalmology.

[17]  D. Edgar,et al.  Methods of measurement of the anterior chamber angle Part 1: Angle closure glaucoma and gonioscopy , 2013 .

[18]  Ramin Khoramnia,et al.  Anterior chamber measurements using Pentacam rotating Scheimpflug camera , 2006, Journal of cataract and refractive surgery.

[19]  Tanuj Dada,et al.  Comparison of anterior segment optical coherence tomography and ultrasound biomicroscopy for assessment of the anterior segment , 2007, Journal of cataract and refractive surgery.

[20]  Tin Aung,et al.  High-definition optical coherence tomography imaging of the iridocorneal angle of the eye. , 2009, Archives of ophthalmology.

[21]  Z. Wang,et al.  Pentacam could be a useful tool for evaluating and qualifying the anterior chamber morphology. , 2014, International journal of clinical and experimental medicine.

[22]  Joseph A Izatt,et al.  Comparison of optical coherence tomography and ultrasound biomicroscopy for detection of narrow anterior chamber angles. , 2005, Archives of ophthalmology.

[23]  Parul Singh,et al.  Gonioscopy: A Review , 2013 .

[24]  Y. Chan,et al.  Configuration of the drainage angle, intraocular pressure, and optic disc cupping in subjects with chronic angle-closure glaucoma. , 2005, Ophthalmology.

[25]  R. Ritch,et al.  Exfoliation syndrome. , 2001, Survey of ophthalmology.

[26]  Hiroshi Ishikawa,et al.  Anterior segment imaging: ultrasound biomicroscopy. , 2004, Ophthalmology clinics of North America.

[27]  Lance Liu Anatomical changes of the anterior chamber angle with anterior-segment optical coherence tomography. , 2008, Archives of ophthalmology.

[28]  C. Cheung,et al.  Repeatability and reproducibility of anterior chamber angle measurement with anterior segment optical coherence tomography , 2007, British Journal of Ophthalmology.

[29]  Tin Aung,et al.  Assessment of the scleral spur in anterior segment optical coherence tomography images. , 2008, Archives of ophthalmology.

[30]  Chungkwon Yoo,et al.  Peripheral Anterior Synechiae and Ultrasound Biomicroscopic Parameters in Angle-Closure Glaucoma Suspects , 2007, Korean journal of ophthalmology : KJO.

[31]  J. Sommerhalder,et al.  Prospective comparison of ultrasound biomicroscopy and anterior segment optical coherence tomography for evaluation of anterior chamber dimensions in European eyes with primary angle closure , 2010, Eye.

[32]  J. Myers Anterior Segment Optical Coherence Tomography as a Screening Tool for the Assessment of the Anterior Segment Angle , 2010 .

[33]  N. Congdon,et al.  Angle-closure glaucoma: impact, etiology, diagnosis, and treatment , 2003, Current opinion in ophthalmology.

[34]  Ningli Wang,et al.  Narrow- and open-angle measurements with anterior-segment optical coherence tomography and Pentacam™. , 2010, Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye.