A microfabricated, optically accessible device to study the effects of mechanical cues on collagen fiber organization

[1]  T. Matsuda,et al.  Mechanical stress induced cellular orientation and phenotypic modulation of 3-D cultured smooth muscle cells. , 1993, ASAIO journal.

[2]  Yu Sun,et al.  Microdevice array-based identification of distinct mechanobiological response profiles in layer-specific valve interstitial cells. , 2013, Integrative biology : quantitative biosciences from nano to macro.

[3]  Timothy M Maul,et al.  Effects of uniaxial cyclic strain on adipose-derived stem cell morphology, proliferation, and differentiation , 2007, Biomechanics and modeling in mechanobiology.

[4]  M Eastwood,et al.  Fibroblast responses to mechanical forces , 1998, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[5]  J. H. Wang,et al.  An Introductory Review of Cell Mechanobiology , 2006, Biomechanics and modeling in mechanobiology.

[6]  Natalia Juncosa-Melvin,et al.  Using functional tissue engineering and bioreactors to mechanically stimulate tissue-engineered constructs. , 2009, Tissue engineering. Part A.

[7]  V. Trinkaus-Randall,et al.  Disorganized collagen scaffold interferes with fibroblast mediated deposition of organized extracellular matrix in vitro , 2012, Biotechnology and bioengineering.

[8]  W. Petroll,et al.  Regulation of corneal fibroblast morphology and collagen reorganization by extracellular matrix mechanical properties. , 2007, Investigative ophthalmology & visual science.

[9]  Tibor Juhasz,et al.  Nonlinear optical macroscopic assessment of 3-D corneal collagen organization and axial biomechanics. , 2011, Investigative ophthalmology & visual science.

[10]  G. Whitesides,et al.  Fabrication of microfluidic systems in poly(dimethylsiloxane) , 2000, Electrophoresis.

[11]  Christopher R Jacobs,et al.  Mechanically induced osteogenic differentiation – the role of RhoA, ROCKII and cytoskeletal dynamics , 2009, Journal of Cell Science.

[12]  B. H. Campbell,et al.  Cyclic Mechanical Stretching of Human Tendon Fibroblasts Increases the Production of Prostaglandin E 2 and Levels of Cyclooxygenase Expression: A Novel In Vitro Model Study , 2003, Connective tissue research.

[13]  Andrew K. Capulli,et al.  Combining Dynamic Stretch and Tunable Stiffness to Probe Cell Mechanobiology In Vitro , 2011, PloS one.

[14]  Shuichi Takayama,et al.  Individually programmable cell stretching microwell arrays actuated by a Braille display. , 2008, Biomaterials.

[15]  G. Benedek,et al.  Theory of transparency of the eye. , 1971, Applied optics.

[16]  H. Hämmerle,et al.  Orientation response of arterial smooth muscle cells to mechanical stimulation. , 1986, European journal of cell biology.

[17]  K. Billiar,et al.  Applying controlled non-uniform deformation for in vitro studies of cell mechanobiology , 2010, Biomechanics and modeling in mechanobiology.

[18]  Yu Sun,et al.  (Micro)managing the mechanical microenvironment. , 2011, Integrative biology : quantitative biosciences from nano to macro.

[19]  Natalia Juncosa-Melvin,et al.  Effect of scaffold material, construct length and mechanical stimulation on the in vitro stiffness of the engineered tendon construct. , 2008, Journal of biomechanics.

[20]  T. Einhorn,et al.  Mechanical stimulation alters tissue differentiation and molecular expression during bone healing , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[21]  Yu Sun,et al.  Microfabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation. , 2010, Lab on a chip.

[22]  A. Ratcliffe,et al.  Bone formation on tissue-engineered cartilage constructs in vivo: effects of chondrocyte viability and mechanical loading. , 2003, Tissue engineering.

[23]  D. Mackenna,et al.  Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. , 2000, Cardiovascular research.

[24]  Robert E Guldberg,et al.  Cyclic mechanical compression increases mineralization of cell-seeded polymer scaffolds in vivo. , 2007, Journal of biomechanical engineering.

[25]  T. Matsuda,et al.  Mechanical Stress-Induced Orientation and Ultrastructural Change of Smooth Muscle Cells Cultured in Three-Dimensional Collagen Lattices , 1994, Cell transplantation.

[26]  J. Jester,et al.  Modulation of cultured corneal keratocyte phenotype by growth factors/cytokines control in vitro contractility and extracellular matrix contraction. , 2003, Experimental eye research.

[27]  H. Hämmerle,et al.  Orientation of cultured arterial smooth muscle cells growing on cyclically stretched substrates. , 1986, Acta anatomica.

[28]  K. J. Grande-Allen,et al.  Effects of static and cyclic loading in regulating extracellular matrix synthesis by cardiovascular cells. , 2006, Cardiovascular research.

[29]  Christopher S. Chen,et al.  Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. , 2004, Developmental cell.

[30]  B. Williams Mechanical influences on vascular smooth muscle cell function , 1998, Journal of hypertension.

[31]  D. Maurice The structure and transparency of the cornea , 1957, The Journal of physiology.

[32]  David J. Mooney,et al.  Cyclic mechanical strain regulates the development of engineered smooth muscle tissue , 1999, Nature Biotechnology.

[33]  F. Ruggiero,et al.  Human corneal fibrillogenesis. Collagen V structural analysis and fibrillar assembly by stromal fibroblasts in culture. , 1996, Investigative ophthalmology & visual science.

[34]  R. Hart,et al.  The transparency of the mammalian cornea , 1970, The Journal of physiology.

[35]  J. Coulombre,et al.  The role of intraocular pressure in the development of the chick eye. IV. Corneal curvature. , 1958, A.M.A. archives of ophthalmology.

[36]  Jeffrey A. Paten,et al.  Design and performance of an optically accessible, low-volume, mechanobioreactor for long-term study of living constructs. , 2011, Tissue engineering. Part C, Methods.

[37]  D. A. Lee,et al.  Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles. , 2005, Biochemical and biophysical research communications.

[38]  Jeffrey W. Ruberti,et al.  Prelude to corneal tissue engineering – Gaining control of collagen organization , 2008, Progress in Retinal and Eye Research.

[39]  F. N. van de Vosse,et al.  Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy , 2011, Biomechanics and Modeling in Mechanobiology.

[40]  J. Coulombre,et al.  Corneal development. I. Corneal transparency. , 1958, Journal of cellular and comparative physiology.

[41]  A. Seth,et al.  Mechanical force regulation of myofibroblast differentiation in cardiac fibroblasts. , 2003, American journal of physiology. Heart and circulatory physiology.