Effects of fructose, sucrose and glucose feeding on plasma insulin concentrations and on adipose-tissue clearing-factor lipase activity in the rat.

The rise in adipose-tissue clearing-factor lipase activity that results from feeding glucose to starved rats cannot be duplicated by giving equicaloric amounts of fructose or sucrose. An inability of the administered fructose and sucrose to raise the plasma insulin concentration probably accounts for this failure in enzyme response.