Chemiluminescence-Based Micro-Total-Analysis System with Amorphous Silicon Photodiodes

In this paper we present a chemiluminescence-based micro-total-analysis system integrating amorphous silicon for on-chip detection as a technically feasible solution to develop “true” lab-on-chip systems, intended as stand-alone devices implementing all the analytical steps from sample preparation to on-chip detection. The achieved performances are comparable to that of the state-of-the-art lab equipment demonstrating that such systems would enable the development of a variety of point-of-care testing systems, opening new analytical application scenarios.