Toxic levels of amyloid beta peptide do not induce VEGF synthesis.

[1]  Xudong Huang,et al.  Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. , 2008, Journal of neurochemistry.

[2]  K. Yudoh,et al.  Distinct signaling pathways are involved in hypoxia‐ and IL‐1‐induced VEGF expression in human articular chondrocytes , 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[3]  K. Nishioka,et al.  Induction of vascular endothelial growth factor and matrix metalloproteinase-3 (stromelysin) by interleukin-1 in human articular chondrocytes and synoviocytes , 2005, Rheumatology International.

[4]  G. Camenisch,et al.  Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. , 2005, Blood.

[5]  K. Tsubota,et al.  TGF-beta1, IL-1beta, and Th2 cytokines stimulate vascular endothelial growth factor production from conjunctival fibroblasts. , 2005, Experimental eye research.

[6]  Y. Gho,et al.  Specific interaction of VEGF165 with β‐amyloid, and its protective effect on β‐amyloid‐induced neurotoxicity , 2005 .

[7]  C. Masters,et al.  Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease β‐amyloid , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[8]  T. Hemnani,et al.  Alzheimer’s disease pathogenesis and therapeutic interventions , 2004, Journal of Clinical Neuroscience.

[9]  Yong Song Gho,et al.  Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer’s disease , 2004, Neurobiology of Aging.

[10]  N. Ferrara,et al.  The biology of VEGF and its receptors , 2003, Nature Medicine.

[11]  N. Inestrosa,et al.  Copper reduction by copper binding proteins and its relation to neurodegenerative diseases , 2003, Biometals.

[12]  Xudong Huang,et al.  Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). , 2002, The Journal of biological chemistry.

[13]  T. K. Hunt,et al.  Copper-induced vascular endothelial growth factor expression and wound healing. , 2002, American journal of physiology. Heart and circulatory physiology.

[14]  Anders Wallin,et al.  Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer’s disease and vascular dementia , 2002, Neurobiology of Aging.

[15]  Jianwei Zhu,et al.  Upregulation of vascular endothelial growth factor by hydrogen peroxide in human colon cancer. , 2002, World journal of gastroenterology.

[16]  C. Roussos,et al.  Reactive oxygen species stimulate VEGF production from C(2)C(12) skeletal myotubes through a PI3K/Akt pathway. , 2001, American journal of physiology. Lung cellular and molecular physiology.

[17]  C. Masters,et al.  Alzheimer's Disease Amyloid-β Binds Copper and Zinc to Generate an Allosterically Ordered Membrane-penetrating Structure Containing Superoxide Dismutase-like Subunits* , 2001, The Journal of Biological Chemistry.

[18]  K. Jin,et al.  Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[19]  K. Jin,et al.  Vascular endothelial growth factor rescues HN33 neural cells from death induced by serum withdrawal , 2000, Journal of Molecular Neuroscience.

[20]  C. Masters,et al.  Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. , 1999, The Journal of biological chemistry.

[21]  Xudong Huang,et al.  The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. , 1999, Biochemistry.

[22]  C. Cobbs,et al.  Hypoxic induction of vascular endothelial growth factor (VEGF) protein in astroglial cultures , 1998, Brain Research.

[23]  R C Hamdy,et al.  Upregulation of vascular endothelial growth factor by H2O2 in rat heart endothelial cells. , 1998, Free radical biology & medicine.

[24]  J. LaManna,et al.  Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia. , 1998, Brain research. Molecular brain research.

[25]  J. D. Robertson,et al.  Copper, iron and zinc in Alzheimer's disease senile plaques , 1998, Journal of the Neurological Sciences.

[26]  Xudong Huang,et al.  Dramatic Aggregation of Alzheimer Aβ by Cu(II) Is Induced by Conditions Representing Physiological Acidosis* , 1998, The Journal of Biological Chemistry.

[27]  G. Perry,et al.  Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[28]  E. Voest,et al.  Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo. , 1996, The Journal of clinical investigation.

[29]  M. Mattson,et al.  A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[30]  C. Vigo‐Pelfrey,et al.  Rapid Communication: Characterization of β‐Amyloid Peptide from Human Cerebrospinal Fluid , 1993 .

[31]  B. Hyman,et al.  The Lack of Accumulation of Senile Plaques or Amyloid Burden in Alzheimer's Disease Suggests a Dynamic Balance Between Amyloid Deposition and Resolution , 1993, Journal of neuropathology and experimental neurology.

[32]  D. Selkoe The molecular pathology of Alzheimer's disease , 1991, Neuron.

[33]  D. A. Brown,et al.  Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  R. Martins,et al.  Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. , 1985, The EMBO journal.

[35]  A. Lumsden,et al.  Effects of TNF-α and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells , 2005 .

[36]  Peter Carmeliet,et al.  VEGF: a critical player in neurodegeneration. , 2004, The Journal of clinical investigation.

[37]  H. Stuerenburg CSF copper concentrations, blood-brain barrier function, and coeruloplasmin synthesis during the treatment of Wilson's disease , 2000, Journal of Neural Transmission.