Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure
暂无分享,去创建一个
A. Sugawara | S. Ito | R. Ito | H. Kagechika | K. Shimizu | W. Rainey | S. Kure | A. Yokoyama | Susumu Suzuki | I. Fujiwara | Akiko Saito-hakoda | R. Parvin | Erika Noro | Hiroki Shimada | Dai Suzuki
[1] A. Sugawara,et al. Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression , 2015, PloS one.
[2] Jiang He,et al. Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries. , 2015, Circulation.
[3] D. Lackland,et al. Global burden of cardiovascular disease and stroke: hypertension at the core. , 2015, The Canadian journal of cardiology.
[4] W. Bollag,et al. The effect of pioglitazone on aldosterone and cortisol production in HAC15 human adrenocortical carcinoma cells , 2014, Molecular and Cellular Endocrinology.
[5] H. Okamura,et al. Angiotensin II Triggers Expression of the Adrenal Gland Zona Glomerulosa-Specific 3β-Hydroxysteroid Dehydrogenase Isoenzyme through De Novo Protein Synthesis of the Orphan Nuclear Receptors NGFIB and NURR1 , 2014, Molecular and Cellular Biology.
[6] Jiang Zhu,et al. Retinoid X receptor agonists inhibit hypertension-induced myocardial hypertrophy by modulating LKB1/AMPK/p70S6K signaling pathway. , 2014, American journal of hypertension.
[7] S. Ito,et al. Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism. , 2014, The Journal of clinical endocrinology and metabolism.
[8] W. Bollag,et al. Acute and chronic regulation of aldosterone production , 2012, Molecular and Cellular Endocrinology.
[9] A. Sugawara,et al. Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production. , 2011, Journal of molecular endocrinology.
[10] Philippe Lefebvre,et al. Retinoid X receptors: common heterodimerization partners with distinct functions , 2010, Trends in Endocrinology & Metabolism.
[11] Y. Wan,et al. Retinoid pathway and cancer therapeutics. , 2010, Advanced drug delivery reviews.
[12] W. Rainey,et al. Role of angiotensin II-induced rapid response genes in the regulation of enzymes needed for aldosterone synthesis. , 2008, Journal of molecular endocrinology.
[13] Daniel W. Jones,et al. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. , 2008, Circulation.
[14] L. R. Howe. Rexinoids and Breast Cancer Prevention , 2007, Clinical Cancer Research.
[15] L. Altucci,et al. RAR and RXR modulation in cancer and metabolic disease , 2007, Nature Reviews Drug Discovery.
[16] R. Dummer,et al. The optimal use of bexarotene in cutaneous T‐cell lymphoma , 2007, The British journal of dermatology.
[17] M. Sporn,et al. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer , 2007, Nature Reviews Cancer.
[18] C. Gomez-Sanchez,et al. Angiotensin II-mediated protein kinase D activation stimulates aldosterone and cortisol secretion in H295R human adrenocortical cells. , 2006, Endocrinology.
[19] A. Itai,et al. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. , 2006, Journal of molecular and cellular cardiology.
[20] H. Kagechika,et al. Synthetic retinoids: recent developments concerning structure and clinical utility. , 2005, Journal of medicinal chemistry.
[21] P. White,et al. The regulation of aldosterone synthase expression , 2004, Molecular and Cellular Endocrinology.
[22] Takashi Suzuki,et al. The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production. , 2004, Molecular endocrinology.
[23] W. Rainey,et al. Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase. , 2002, Endocrinology.
[24] Y. Hashimoto,et al. Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions. , 2002, Journal of medicinal chemistry.
[25] C Clyne,et al. Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1. , 2002, Journal of molecular endocrinology.
[26] A. Sugawara,et al. Transcription Suppression of Thromboxane Receptor Gene by Peroxisome Proliferator-activated Receptor-γ via an Interaction with Sp1 in Vascular Smooth Muscle Cells* , 2002, The Journal of Biological Chemistry.
[27] H. Rasmussen,et al. Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation , 2001, Molecular and Cellular Endocrinology.
[28] D. B. Hales,et al. The in Vivo Effects of Adrenocorticotropin and Sodium Restriction on the Formation of Different Species of Steroidogenic Acute Regulatory Protein in Rat Adrenal1. , 1999, Endocrinology.
[29] N. Gretz,et al. Specific Regulation of StAR Expression in the Rat Adrenal Zona Glomerulosa: an In Situ Hybridization Study , 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[30] I. Bird,et al. Protein kinase A, protein kinase C, and Ca(2+)-regulated expression of 21-hydroxylase cytochrome P450 in H295R human adrenocortical cells. , 1998, The Journal of clinical endocrinology and metabolism.
[31] I. Friedberg,et al. Submitochondrial Distribution of Three Key Steroidogenic Proteins (Steroidogenic Acute Regulatory Protein and Cytochrome P450scc and 3β-Hydroxysteroid Dehydrogenase Isomerase Enzymes) upon Stimulation by Intracellular Calcium in Adrenal Glomerulosa Cells* , 1997, The Journal of Biological Chemistry.
[32] J. Mathis,et al. Differential regulation of 11 beta-hydroxylase and aldosterone synthase in human adrenocortical H295R cells. , 1996, Molecular and cellular endocrinology.
[33] I. Bird,et al. Differential control of 17 alpha-hydroxylase and 3 beta-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells. , 1996, The Journal of clinical endocrinology and metabolism.
[34] D. Stocco,et al. The steroidogenic acute regulatory protein is induced by angiotensin II and K+ in H295R adrenocortical cells , 1995, Molecular and Cellular Endocrinology.
[35] J. Ross,et al. Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[36] R. Evans,et al. RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. , 1994, Genes & development.
[37] A. Fukamizu,et al. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. , 1993, The Journal of biological chemistry.
[38] P. White,et al. Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta). , 1989, The Journal of biological chemistry.
[39] G. Tsujimoto,et al. Salt-sensitive hypertension in circadian clock–deficient Cry-null mice involves dysregulated adrenal Hsd3b6 , 2010, Nature Medicine.
[40] Xiuwen Tang,et al. Bexarotene: a promising anticancer agent , 2009, Cancer Chemotherapy and Pharmacology.
[41] D. B. Hales,et al. The in vivo effects of adrenocorticotropin and sodium restriction on the formation of the different species of steroidogenic acute regulatory protein in rat adrenal. , 1999, Endocrinology.
[42] W. Rainey,et al. Regulation of 3 beta-hydroxysteroid dehydrogenase in adrenocortical cells: effects of angiotensin-II and transforming growth factor beta. , 1991, Endocrine research.