Regional anesthesia for cardiac surgery.

PURPOSE OF REVIEW Anesthesia for cardiac surgery has traditionally utilized high-dose opioids to blunt the sympathetic response to surgery. However, recent data suggest that opioids prolong postoperative intubation, leading to increased morbidity. Given the increased risk of opioid dependency after in-hospital exposure to opioids, coupled with an increase in morbidity, regional techniques offer an adjunct for perioperative analgesia. The aim of this review is to describe conventional and emerging regional techniques for cardiac surgery. RECENT FINDINGS Well-studied techniques such as thoracic epidurals and paravertebral blocks are relatively low risk despite lack of widespread adoption. Benefits include reduced opioid exposure after paravertebral blocks and reduced risk of perioperative myocardial infarction after epidurals. To further lower the risk of epidural hematoma and pneumothorax, new regional techniques have been studied, including parasternal, pectoral, and erector spinae plane blocks. Because these are superficial compared with paravertebral and epidural blocks, they may have even lower risks of hematoma formation, whereas patients are anticoagulated on cardiopulmonary bypass. Efficacy data have been promising, although large and generalizable studies are lacking. SUMMARY New regional techniques for cardiac surgery may be potent perioperative analgesic adjuncts, but well-designed studies are needed to quantify the effectiveness and safety of these blocks.

[1]  Shenglei Zhang,et al.  Risk factors for ventilator-associated events: A prospective cohort study. , 2019, American journal of infection control.

[2]  X. Capdevila,et al.  Ultrasound-Guided Continuous Thoracic Erector Spinae Plane Block Within an Enhanced Recovery Program Is Associated with Decreased Opioid Consumption and Improved Patient Postoperative Rehabilitation After Open Cardiac Surgery-A Patient-Matched, Controlled Before-and-After Study. , 2019, Journal of cardiothoracic and vascular anesthesia.

[3]  N. Raj Regional anesthesia for sternotomy and bypass—Beyond the epidural , 2019, Paediatric anaesthesia.

[4]  K. Chin,et al.  Continuous Erector Spinae Plane Block as an Effective Analgesic Option in Anticoagulated Patients After Left Ventricular Assist Device Implantation: A Case Series. , 2019, Journal of cardiothoracic and vascular anesthesia.

[5]  Pectoralis and Serratus Plane Blocks , 2019, Military Advanced Regional Anesthesia and Analgesia Handbook.

[6]  S. Kopp,et al.  Epidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass. , 2019, The Cochrane database of systematic reviews.

[7]  Thomas J. Caruso,et al.  Toward Opioid-Free Fast Track for Pediatric Congenital Cardiac Surgery. , 2019, Journal of cardiothoracic and vascular anesthesia.

[8]  T. K. Harrison,et al.  Care of the Patient With a Peripheral Nerve Block , 2019, Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses.

[9]  A. Mittnacht Fascial Plane Blocks in Cardiac Surgery: Same but Different. , 2019, Journal of cardiothoracic and vascular anesthesia.

[10]  S. Chauhan,et al.  Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial. , 2019, Journal of Cardiothoracic and Vascular Anesthesia.

[11]  A. Gregory,et al.  Erector Spinae Plane Block for Open-Heart Surgery: A Potential Tool for Improved Analgesia. , 2019, Journal of cardiothoracic and vascular anesthesia.

[12]  S. Chauhan,et al.  Comparison of the Efficacy of Ultrasound-Guided Serratus Anterior Plane Block, Pectoral Nerves II Block, and Intercostal Nerve Block for the Management of Postoperative Thoracotomy Pain After Pediatric Cardiac Surgery. , 2019, Journal of cardiothoracic and vascular anesthesia.

[13]  S. Suresh,et al.  Regional Analgesia Added to General Anesthesia Compared With General Anesthesia Plus Systemic Analgesia for Cardiac Surgery in Children: A Systematic Review and Meta-analysis of Randomized Clinical Trials , 2019, Anesthesia and analgesia.

[14]  Linlin Song,et al.  Inadvertent posterior intercostal artery puncture and haemorrhage after ultrasound-guided thoracic paravertebral block: a case report , 2018, BMC Anesthesiology.

[15]  B. Tsui,et al.  Opioid-Free Ultra-Fast-Track On-Pump Coronary Artery Bypass Grafting Using Erector Spinae Plane Catheters. , 2018, Journal of cardiothoracic and vascular anesthesia.

[16]  Katherine Taylor,et al.  A Systematic Review of Caudal Anesthesia and Postoperative Outcomes in Pediatric Cardiac Surgery Patients , 2018, Seminars in cardiothoracic and vascular anesthesia.

[17]  Thomas J. Caruso,et al.  Bilateral automatized intermittent bolus erector spinae plane analgesic blocks for sternotomy in a cardiac patient who underwent cardiopulmonary bypass: A new era of Cardiac Regional Anesthesia. , 2018, Journal of clinical anesthesia.

[18]  H. C. Kose,et al.  Lumbar versus thoracic erector spinae plane block: Similar nomenclature, different mechanism of action. , 2018, Journal of clinical anesthesia.

[19]  Naveen Singh,et al.  Comparison of Continuous Thoracic Epidural Analgesia with Bilateral Erector Spinae Plane Block for Perioperative Pain Management in Cardiac Surgery , 2018, Annals of cardiac anaesthesia.

[20]  Naveen Singh,et al.  Efficacy of Bilateral Pectoralis Nerve Block for Ultrafast Tracking and Postoperative Pain Management in Cardiac Surgery , 2018, Annals of cardiac anaesthesia.

[21]  M. Chakravarthy Regional Analgesia in Cardiothoracic Surgery: A Changing Paradigm Toward Opioid-Free Anesthesia? , 2018, Annals of cardiac anaesthesia.

[22]  B. Tsui A systematic approach to scoring bleeding risk in regional anesthesia procedures. , 2018, Journal of clinical anesthesia.

[23]  R. J. Ramamurthi,et al.  Bilateral continuous erector spinae plane blocks for sternotomy in a pediatric cardiac patient. , 2018, Journal of clinical anesthesia.

[24]  U. Pollak,et al.  Pediatric Cardiac Surgery and Pain Management: After 40 Years in the Desert, Have We Reached the Promised Land? , 2018, World journal for pediatric & congenital heart surgery.

[25]  A. Gregory,et al.  Enhanced Recovery for Cardiac Surgery. , 2018, Journal of cardiothoracic and vascular anesthesia.

[26]  S. Kopp,et al.  Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition) , 2018, Regional Anesthesia & Pain Medicine.

[27]  T. Kitamura,et al.  Early Extubation in the Operating Room after Congenital Open-Heart Surgery. , 2018, International heart journal.

[28]  M. Crawford,et al.  Use of Serratus Plane Block for Repair of Coarctation of Aorta: A Report of 3 Cases , 2018, Regional Anesthesia & Pain Medicine.

[29]  J. Cros,et al.  Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial , 2017, Regional Anesthesia & Pain Medicine.

[30]  H. Sakamoto,et al.  A case series of continuous paravertebral block in minimally invasive cardiac surgery , 2017, JA Clinical Reports.

[31]  H. Ueshima,et al.  Clinical experiences of Ultrasound-guided transversus thoracic muscle plane block for children. , 2017, Journal of clinical anesthesia.

[32]  J. Corrente,et al.  Perioperative and anesthesia-related cardiac arrests in geriatric patients: a systematic review using meta-regression analysis , 2017, Scientific Reports.

[33]  K. Chin,et al.  The analgesic efficacy of pre‐operative bilateral erector spinae plane (ESP) blocks in patients having ventral hernia repair , 2017, Anaesthesia.

[34]  H. Otake,et al.  Continuous transversus thoracic muscle plane block is effective for the median sternotomy. , 2017, Journal of clinical anesthesia.

[35]  A. Khalil,et al.  Ultrasound-Guided Serratus Anterior Plane Block Versus Thoracic Epidural Analgesia for Thoracotomy Pain. , 2017, Journal of cardiothoracic and vascular anesthesia.

[36]  A. Ho,et al.  Local Anaesthetic Toxicity after Bilateral Thoracic Paravertebral Block in Patients Undergoing Coronary Artery Bypass Surgery , 2016, Anaesthesia and intensive care.

[37]  K. Chin,et al.  The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain , 2016, Regional Anesthesia & Pain Medicine.

[38]  P. Stefanovich,et al.  Ultrasound-Guided Thoracic Paravertebral Blockade: A Retrospective Study of the Incidence of Complications , 2016, Anesthesia and analgesia.

[39]  H. Otake,et al.  The ultrasound-guided transversus thoracic muscle plane block is effective for the median sternotomy. , 2016, Journal of clinical anesthesia.

[40]  S. Gates,et al.  Paravertebral block versus thoracic epidural for patients undergoing thoracotomy. , 2016, The Cochrane database of systematic reviews.

[41]  G. Nolan,et al.  Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery , 2015, Anesthesiology.

[42]  H. Otake,et al.  Ultrasound-guided transversus thoracic muscle plane block: a cadaveric study of the spread of injectate. , 2015, Journal of clinical anesthesia.

[43]  A. Zangrillo,et al.  Benefits and risks of epidural analgesia in cardiac surgery. , 2015, British journal of anaesthesia.

[44]  G. Saydam,et al.  Does High Thoracic Epidural Analgesia with Levobupivacaine Preserve Myocardium? A Prospective Randomized Study , 2015, BioMed research international.

[45]  H. Ueshima,et al.  Pectoral Nerve Blocks for Breast Cancer Surgery: A Methodological Evaluation , 2015, Regional Anesthesia & Pain Medicine.

[46]  Stuart B. Goodman,et al.  Clinical recovery from surgery correlates with single-cell immune signatures , 2014, Science Translational Medicine.

[47]  D. Bichell,et al.  Postoperative complications and association with outcomes in pediatric cardiac surgery. , 2014, The Journal of thoracic and cardiovascular surgery.

[48]  P. Choi,et al.  Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews. , 2014, The Cochrane database of systematic reviews.

[49]  S. Chauhan,et al.  Parasternal intercostal block with ropivacaine for postoperative analgesia in pediatric patients undergoing cardiac surgery: a double-blind, randomized, controlled study. , 2012, Journal of cardiothoracic and vascular anesthesia.

[50]  John S Campos,et al.  Anesthesia-Related Cardiac Arrest in Children with Heart Disease: Data from the Pediatric Perioperative Cardiac Arrest (POCA) Registry , 2010, Anesthesia and analgesia.

[51]  E. Bignami,et al.  A comparison of epidural vs. paravertebral blockade in thoracic surgery. , 2009, Minerva anestesiologica.

[52]  G. Gildengorin,et al.  A Prospective Study of Ventilator-Associated Pneumonia in Children , 2009, Pediatrics.

[53]  J. García-Bengochea,et al.  High thoracic epidural blockade increases myocardial oxygen availability in coronary surgery patients , 2006, Acta anaesthesiologica Scandinavica.

[54]  R. Heyderman,et al.  Spinal Anesthesia with an Indwelling Catheter Reduces the Stress Response in Pediatric Open Heart Surgery , 2005, Anesthesiology.

[55]  D. Schroeder,et al.  Cardiac Arrest During Neuraxial Anesthesia: Frequency and Predisposing Factors Associated with Survival , 2005, Anesthesia and analgesia.

[56]  D. Kopacz,et al.  Parasternal Block and Local Anesthetic Infiltration with Levobupivacaine After Cardiac Surgery with Desflurane: The Effect on Postoperative Pain, Pulmonary Function, and Tracheal Extubation Times , 2005, Anesthesia and analgesia.

[57]  Robert W Emery,et al.  Opposite trends in coronary artery and valve surgery in a large multisurgeon practice, 1979-1999. , 2004, The Annals of thoracic surgery.

[58]  S. Hirai Systemic inflammatory response syndrome after cardiac surgery under cardiopulmonary bypass. , 2003, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia.

[59]  H. Grocott,et al.  High Spinal Anesthesia for Cardiac Surgery: Effects on &bgr;-Adrenergic Receptor Function, Stress Response, and Hemodynamics , 2003, Anesthesiology.

[60]  P. Lönnqvist,et al.  The effect of posture on cerebral oxygenation during abdominal surgery , 2001, Anaesthesia.

[61]  E. Marinopoulou,et al.  Intercostal Nerve Block with Bupivacaine for Post-Thoracotomy Pain Relief in Children , 2001, European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

[62]  M. Tryba,et al.  Rückenmarksnahe Regionalanästhesie und niedermolekulare Heparine: Pro und Kontra , 1993 .

[63]  A. Baxter,et al.  Continuous intercostal blockade after cardiac surgery. , 1987, British journal of anaesthesia.

[64]  Y. Oh,et al.  Efficacy of Ultrasound-Guided Serratus Plane Block on Postoperative Quality of Recovery and Analgesia After Video-Assisted Thoracic Surgery: A Randomized, Triple-Blind, Placebo-Controlled Study , 2018, Anesthesia and analgesia.

[65]  D. Unić-Stojanović,et al.  Blood transfusion in cardiac surgery--does the choice of anesthesia or type of surgery matter? , 2013, Vojnosanitetski pregled.

[66]  C. Prusinkiewicz,et al.  Neuraxial anesthesia for cardiac surgery: thoracic epidural and high spinal anesthesia - why is it different? , 2011, HSR proceedings in intensive care & cardiovascular anesthesia.

[67]  R. Lakshmy,et al.  Caudal epidural sufentanil and bupivacaine decreases stress response in paediatric cardiac surgery. , 2009, Annals of cardiac anaesthesia.

[68]  A. Pensado Castiñeiras,et al.  [Early extubation with caudal morphine after pediatric heart surgery]. , 2003, Revista espanola de anestesiologia y reanimacion.