Estimated Prevalence of Opioid Use Disorder in Massachusetts, 2011-2015: A Capture-Recapture Analysis

Objectives To estimate the annual prevalence of opioid use disorder (OUD) in Massachusetts from 2011 to 2015. Methods We performed a multisample stratified capture-recapture analysis to estimate OUD prevalence in Massachusetts. Individuals identified from 6 administrative databases for 2011 to 2012 and 7 databases for 2013 to 2015 were linked at the individual level and included in the analysis. Individuals were stratified by age group, sex, and county of residence. Results The OUD prevalence in Massachusetts among people aged 11 years or older was 2.72% in 2011 and 2.87% in 2012. Between 2013 and 2015, the prevalence increased from 3.87% to 4.60%. The greatest increase in prevalence was observed among those in the youngest age group (11-25 years), a 76% increase from 2011 to 2012 and a 42% increase from 2013 to 2015. Conclusions In Massachusetts, the OUD prevalence was 4.6% among people 11 years or older in 2015. The number of individuals with OUD is likely increasing, particularly among young people.

[1]  Cheng-Chung Fang,et al.  Underreporting of illicit drug use by patients at emergency departments as revealed by two-tiered urinalysis. , 2006, Addictive behaviors.

[2]  Taylor B. Seybolt,et al.  Counting civilian casualties : an introduction to recording and estimating nonmilitary deaths in conflict , 2013 .

[3]  S. Galea,et al.  Understanding the rural-urban differences in nonmedical prescription opioid use and abuse in the United States. , 2014, American journal of public health.

[4]  G. Seber A Review of Estimating Animal Abundance II , 1992 .

[5]  R. Stone Pregnant women and substance use: fear, stigma, and barriers to care , 2015, Health & Justice.

[6]  He Zhu,et al.  Treatment utilization among persons with opioid use disorder in the United States. , 2016, Drug and alcohol dependence.

[7]  B. Marshall,et al.  Injection drug use and overdose among young adults who use prescription opioids non-medically. , 2018, Addictive behaviors.

[8]  Daniel Ciccarone,et al.  Fentanyl in the US heroin supply: A rapidly changing risk environment. , 2017, The International journal on drug policy.

[9]  M. Stein,et al.  Looking for the uninsured in Massachusetts? Check opioid dependent persons seeking detoxification. , 2014, Drug and alcohol dependence.

[10]  J. Zibbell,et al.  Increases in Drug and Opioid Overdose Deaths—United States, 2000–2014 , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[11]  Daniel Ciccarone,et al.  US regional and demographic differences in prescription opioid and heroin-related overdose hospitalizations. , 2017, The International journal on drug policy.

[12]  Debra Houry,et al.  New Data on Opioid Use and Prescribing in the United States. , 2017, JAMA.

[13]  I. Gemmell,et al.  Capture-recapture estimates of problem drug use and the use of simulation based confidence intervals in a stratified analysis , 2004, Journal of Epidemiology and Community Health.

[14]  James H. Ford,et al.  Massachusetts's experience suggests coverage alone is insufficient to increase addiction disorders treatment. , 2012, Health affairs.

[15]  G. Seber The estimation of animal abundance and related parameters , 1974 .

[16]  Al Ozonoff,et al.  Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis , 2013, BMJ.

[17]  Regina Y. Liu,et al.  Using i.i.d. bootstrap inference for general non-i.i.d. models , 1995 .

[18]  M. Shattell,et al.  Harm reduction: compassionate care of persons with addictions. , 2013, Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses.

[19]  D. Holtzman,et al.  Increases in Acute Hepatitis C Virus Infection Related to a Growing Opioid Epidemic and Associated Injection Drug Use, United States, 2004 to 2014 , 2018, American journal of public health.

[20]  Mona Doshani,et al.  Using Population Based Hospitalization Data to Monitor Increases in Conditions Causing Morbidity Among Persons Who Inject Drugs , 2018, Journal of Community Health.

[21]  A. Morrison,et al.  Capture-recapture: a useful methodological tool for counting traffic related injuries? , 2000, Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention.

[22]  F. Blyth,et al.  Defining problematic pharmaceutical opioid use among people prescribed opioids for chronic noncancer pain: do different measures identify the same patients? , 2016, Pain.

[23]  R. Matthew Gladden,et al.  Characteristics of Fentanyl Overdose — Massachusetts, 2014–2016 , 2017, MMWR. Morbidity and mortality weekly report.

[24]  H. Akaike A new look at the statistical model identification , 1974 .

[25]  S. Mars,et al.  Nationwide increase in hospitalizations for heroin-related soft tissue infections: Associations with structural market conditions. , 2016, Drug and alcohol dependence.

[26]  Alain Origer Prevalence of Problem Drug Use and Injecting Drug Use in Luxembourg: A Longitudinal and Methodological Perspective , 2012, European Addiction Research.

[27]  Ronald E. LaPorte,et al.  Capture-recapture and multiple-record systems estimation I: History and theoretical development ( Review ) , 1995 .