A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction

[1]  J. Widom,et al.  The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription , 2009, The Journal of experimental medicine.

[2]  D. Schatz,et al.  Balancing AID and DNA repair during somatic hypermutation. , 2009, Trends in immunology.

[3]  J. Potter,et al.  Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study. , 2009, Gastroenterology.

[4]  B. Cairns,et al.  DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45 , 2008, Cell.

[5]  T. Honjo,et al.  Organ‐specific profiles of genetic changes in cancers caused by activation‐induced cytidine deaminase expression , 2008, International journal of cancer.

[6]  M. Nussenzweig,et al.  AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations , 2008, Cell.

[7]  G. Bhagat,et al.  Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. , 2008, Cancer cell.

[8]  T. Honjo,et al.  Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. , 2008, Gastroenterology.

[9]  H. Seno,et al.  Mechanism for gastric cancer development by Helicobacter pylori infection , 2008, Journal of gastroenterology and hepatology.

[10]  P. Allavena,et al.  Cancer-related inflammation , 2008, Nature.

[11]  W. Park,et al.  Activation-Induced Cytidine Deaminase Expression in Gastric Cancer , 2008, Tumor Biology.

[12]  K. Kinoshita,et al.  Activation‐induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma , 2008, Hepatology.

[13]  D. Schatz,et al.  Two levels of protection for the B cell genome during somatic hypermutation , 2008, Nature.

[14]  M. Nussenzweig,et al.  A role for AID in chromosome translocations between c-myc and the IgH variable region , 2007, The Journal of experimental medicine.

[15]  T. Honjo,et al.  Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling , 2007, Oncogene.

[16]  K. Sugano,et al.  Novel interleukin‐4 and interleukin‐1 receptor antagonist gene variations associated with non‐cardia gastric cancer in Japan: Comprehensive analysis of 207 polymorphisms of 11 cytokine genes , 2007, Journal of gastroenterology and hepatology.

[17]  Takeshi Azuma,et al.  Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium , 2007, Nature Medicine.

[18]  E. Birney,et al.  Patterns of somatic mutation in human cancer genomes , 2007, Nature.

[19]  K. Kinoshita,et al.  Expression of activation‐induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis , 2007, International journal of cancer.

[20]  G. Parmigiani,et al.  The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.

[21]  A. Yasui,et al.  MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes , 2005, The Journal of experimental medicine.

[22]  John Bertin,et al.  Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island , 2004, Nature Immunology.

[23]  Takeshi Azuma,et al.  Helicobacter pylori CagA Induces Ras-independent Morphogenetic Response through SHP-2 Recruitment and Activation* , 2004, Journal of Biological Chemistry.

[24]  E. Friedberg,et al.  The role of endogenous and exogenous DNA damage and mutagenesis. , 2004, Current opinion in genetics & development.

[25]  N. Chiorazzi,et al.  Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone. , 2003, Blood.

[26]  N. Kakazu,et al.  Constitutive Expression of AID Leads to Tumorigenesis , 2003, The Journal of experimental medicine.

[27]  W. Klapper,et al.  Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas. , 2003, Blood.

[28]  S. Narumiya,et al.  Cyclooxygenase 2- and prostaglandin E2 receptor EP2-dependent angiogenesis in ApcΔ716 mouse intestinal polyps , 2002 .

[29]  Y. Shiratori,et al.  Distinct Mechanism of Helicobacter pylori-mediated NF-κB Activation between Gastric Cancer Cells and Monocytic Cells* , 2001, The Journal of Biological Chemistry.

[30]  J. Hoeijmakers.  Genome maintenance mechanisms for preventing cancer , 2001, Nature.

[31]  T. Honjo,et al.  Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme , 2000, Cell.

[32]  T. Honjo,et al.  Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells* , 1999, The Journal of Biological Chemistry.

[33]  K. Shimotohno,et al.  Hepatitis C Virus Core Protein Inhibits Fas- and Tumor Necrosis Factor Alpha-Mediated Apoptosis via NF-κB Activation , 1999, Journal of Virology.

[34]  J. L. Bos,et al.  ras oncogenes in human cancer: a review. , 1989, Cancer research.

[35]  高井 淳.  A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations , 2010 .

[36]  S. Narumiya,et al.  Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps. , 2002, Cancer research.

[37]  K. Shimotohno,et al.  Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation. , 1999, Journal of virology.