Case Report of 74-Year-Old Female with Microcystic Adnexal Carcinoma, a Rare and Locally Invasive Neoplasm, with Multiple Recurrences and Review of the Literature

Microcystic adnexal carcinomas (MAC) are a very rare form of locally invading neoplasms. This paper reports a case of a 74-year-old female diagnosed with a MAC neoplasm localized to the left upper cheek; she was treated with both surgery and radiotherapy. The patient had two recurrences after surgical excisions with the second excision being coupled with radiotherapy. This report asses the rarity of this disease, which may lead to misdiagnosis, and the optimal treatment to minimize the possibility of known high recurrence rates. MAC is not considered a highly metastatic neoplasm; however, potential for metastasis exists, as discussed in this case.

[1]  Jingxin Chen,et al.  Microcystic adnexal carcinoma in a non-Caucasian patient: A case report and review of the literature. , 2016, Oncology letters.

[2]  J. Rustemeyer,et al.  Microcystic adnexal carcinoma of the upper lip misdiagnosed benign desmoplastic trichoepithelioma , 2012, Oral and Maxillofacial Surgery.

[3]  L. Wilson,et al.  Surveillance, Epidemiology, and End Results (SEER) Database Analysis of Microcystic Adnexal Carcinoma (Sclerosing Sweat Duct Carcinoma) of the Skin , 2009, American journal of clinical oncology.

[4]  J. Shang,et al.  [Microcystic adnexal carcinoma: report of two cases]. , 2009, Zhonghua bing li xue za zhi = Chinese journal of pathology.

[5]  P. Petrow,et al.  Microcystic Adnexal Carcinoma: Report of Seven Cases Including One with Lung Metastasis , 2006, Dermatology.

[6]  D. Selva,et al.  Microcystic adnexal carcinoma: treatment with Mohs micrographic surgery. , 2005, Journal of the American Academy of Dermatology.

[7]  Y. Kitajima,et al.  Microcystic Adnexal Carcinoma with Lymph Node Metastasis , 2004, Dermatology.

[8]  J. Ratz,et al.  Microcystic adnexal carcinoma: First reported case in an African American man. , 2001, Journal of the American Academy of Dermatology.

[9]  S. Snow,et al.  Microcystic Adnexal Carcinoma: Report of 13 Cases and Review of the Literature , 2001, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[10]  M. Singer,et al.  Microcystic adnexal carcinoma: forty-eight cases, their treatment, and their outcome. , 2000, Archives of dermatology.

[11]  P. Robins,et al.  Microcystic adnexal carcinoma: collaborative series review and update. , 1999, Journal of the American Academy of Dermatology.

[12]  L. Goldberg,et al.  Microcystic adnexal carcinoma. Ten cases treated by Mohs micrographic surgery. , 1994, The Journal of dermatologic surgery and oncology.

[13]  S. Mills,et al.  Microcystic adnexal carcinoma. , 1984, Journal of the American Academy of Dermatology.