Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity
暂无分享,去创建一个
C. Limatola | A. Paiardini | F. Cutruzzolà | A. Macone | A. Baracca | G. Sgarbi | G. Solaini | M. Magnifico | C. Lauro | A. Tramutola | M. Perluigi | A. Paone | Amani Bouzidi | G. Giardina | G. Boumis | S. Rinaldo | C. Lanzillotta | Francesca Romana Liberati | Chiara Lanzillotta | Antonella Tramutola
[1] D. Boison,et al. Sarcosine Suppresses Epileptogenesis in Rats With Effects on Hippocampal DNA Methylation , 2020, Frontiers in Molecular Neuroscience.
[2] M. Salmerón-Sánchez,et al. The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis , 2020, Nature Metabolism.
[3] J. Moscat,et al. The complexity of the serine glycine one-carbon pathway in cancer , 2019, The Journal of cell biology.
[4] Yana Qi,et al. Distribution Of Brain Metastasis From Lung Cancer , 2019, Cancer management and research.
[5] M. Yuneva,et al. Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion , 2019, Molecular metabolism.
[6] C. Limatola,et al. Fractalkine Modulates Microglia Metabolism in Brain Ischemia , 2019, Front. Cell. Neurosci..
[7] M. V. Vander Heiden,et al. Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation , 2019, Nature Metabolism.
[8] C. Nardella,et al. Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties. , 2018, Biochemistry.
[9] D. Butterfield,et al. Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome , 2018, Translational Neurodegeneration.
[10] S. Hladky,et al. Elimination of substances from the brain parenchyma: efflux via perivascular pathways and via the blood–brain barrier , 2018, Fluids and Barriers of the CNS.
[11] A. J. Scott,et al. AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization , 2018, The Journal of Biological Chemistry.
[12] A. Paiardini,et al. The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells , 2018, The FEBS journal.
[13] M. Arese,et al. Nonylphenol and Octylphenol Differently Affect Cell Redox Balance by Modulating the Nitric Oxide Signaling , 2018, Oxidative medicine and cellular longevity.
[14] S. Colgan,et al. Hypoxanthine is a checkpoint stress metabolite in colonic epithelial energy modulation and barrier function , 2018, The Journal of Biological Chemistry.
[15] A. Costanzini,et al. The role of the ATPase inhibitor factor 1 (IF1) in cancer cells adaptation to hypoxia and anoxia. , 2018, Biochimica et biophysica acta. Bioenergetics.
[16] U. Staubli,et al. Phenylglycine analogs are inhibitors of the neutral amino acid transporters ASCT1 and ASCT2 and enhance NMDA receptor-mediated LTP in rat visual cortex slices , 2017, Neuropharmacology.
[17] I. Amelio,et al. Exploiting tumour addiction with a serine and glycine-free diet , 2017, Cell Death and Differentiation.
[18] O. Sansom,et al. Modulating the therapeutic response of tumours to dietary serine and glycine starvation , 2017, Nature.
[19] Cheng Li,et al. GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses , 2017, Nucleic Acids Res..
[20] W. Jung,et al. Differential Site-Based Expression of Pentose Phosphate Pathway-Related Proteins among Breast Cancer Metastases , 2017, Disease markers.
[21] Joshua D Rabinowitz,et al. One-Carbon Metabolism in Health and Disease. , 2017, Cell metabolism.
[22] E. Laczko,et al. Brain interstitial fluid glutamine homeostasis is controlled by blood–brain barrier SLC7A5/LAT1 amino acid transporter , 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[23] N. Heintz,et al. AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion , 2016, Molecular biology of the cell.
[24] Xiaozhuo Chen,et al. Extracellular ATP a New Player in Cancer Metabolism: NSCLC Cells Internalize ATP In Vitro and In Vivo Using Multiple Endocytic Mechanisms , 2016, Molecular Cancer Research.
[25] M. V. Vander Heiden,et al. The importance of serine metabolism in cancer , 2016, The Journal of cell biology.
[26] J. Rabinowitz,et al. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. , 2016, Cell metabolism.
[27] S. Manalis,et al. Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells. , 2016, Developmental cell.
[28] Tianyi Yang,et al. A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells , 2015, Oncotarget.
[29] Terry A. Gaige,et al. Automated live cell imaging of cell migration across a microfluidic-controlled chemoattractant gradient , 2015, Nature Methods.
[30] Helena Marzo-Ortega,et al. Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis , 2015, Nature Communications.
[31] S. Gibson,et al. Differential cellular responses induced by dorsomorphin and LDN‐193189 in chemotherapy‐sensitive and chemotherapy‐resistant human epithelial ovarian cancer cells , 2015, International journal of cancer.
[32] L. Cantley,et al. Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain. , 2015, Cancer research.
[33] S. Higo,et al. Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5 , 2015, Nature Communications.
[34] A. Paiardini,et al. SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation , 2014, Cell Death and Disease.
[35] M. Morello,et al. Bioinformatics analysis of the serine and glycine pathway in cancer cells , 2014, Oncotarget.
[36] I. Amelio,et al. Serine and glycine metabolism in cancer☆ , 2014, Trends in biochemical sciences.
[37] G. Martinelli,et al. Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma , 2014, Oncotarget.
[38] N. Vaidehi,et al. Human breast cancer metastases to the brain display GABAergic properties in the neural niche , 2014, Proceedings of the National Academy of Sciences.
[39] Joshua M. Stuart,et al. The Cancer Genome Atlas Pan-Cancer analysis project , 2013, Nature Genetics.
[40] Karen Blyth,et al. Serine starvation induces stress and p53 dependent metabolic remodeling in cancer cells , 2012, Nature.
[41] Keisuke Sawada,et al. Autocrine regulation of TGF-&bgr;1-induced cell migration by exocytosis of ATP and activation of P2 receptors in human lung cancer cells , 2012, Journal of Cell Science.
[42] G. Filomeni,et al. Redox implications of AMPK-mediated signal transduction beyond energetic clues , 2012, Journal of Cell Science.
[43] R. Dhir,et al. Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasion. , 2010, Cancer research.
[44] P. Febbo,et al. Use of gene expression signatures to identify origin of primary and therapeutic strategies for patients with advanced solid tumors. , 2010 .
[45] P. Stover,et al. Cytoplasmic Serine Hydroxymethyltransferase Regulates the Metabolic Partitioning of Methylenetetrahydrofolate but Is Not Essential in Mice* , 2008, Journal of Biological Chemistry.
[46] H. Johnson,et al. A comparison of 'traditional' and multimedia information systems development practices , 2003, Inf. Softw. Technol..
[47] H. Satoh,et al. Specific organ metastases and survival in metastatic non-small-cell lung cancer. , 2015, Molecular and clinical oncology.
[48] I. Molnár-Perl,et al. GC-MS of amino acids as their trimethylsilyl/t-butyldimethylsilyl Derivatives: In model solutions III , 2000 .
[49] S. Mukerji,et al. Lactate release from cultured astrocytes and neurons: A comparison , 1988, Glia.