Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis

[1]  P. Eilers,et al.  Progression and Tumor Heterogeneity Analysis in Early Rectal Cancer , 2008, Clinical Cancer Research.

[2]  H. Morreau,et al.  Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas , 2007, The Journal of pathology.

[3]  Ekaterina S Jordanova,et al.  Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer , 2007, BMC Genomics.

[4]  E. Korn,et al.  Stage‐specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis , 2007, Genes, chromosomes & cancer.

[5]  Daniel F Hayes,et al.  ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[6]  Dana M. Brantley-Sieders,et al.  Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice. , 2006, Cancer research.

[7]  C. Pilarsky,et al.  A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer , 2006, Molecular Cancer.

[8]  T. Frebourg,et al.  Contribution of the BOP1 gene, located on 8q24, to colorectal tumorigenesis , 2006, Genes, chromosomes & cancer.

[9]  Z. Szallasi,et al.  A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers , 2006, Nature Genetics.

[10]  E. Kremmer,et al.  Dominant-negative Pes1 mutants inhibit ribosomal RNA processing and cell proliferation via incorporation into the PeBoW-complex , 2006, Nucleic acids research.

[11]  Howard Y. Chang,et al.  Genetic regulators of large-scale transcriptional signatures in cancer , 2006, Nature Genetics.

[12]  R. Fodde,et al.  Smad4 haploinsufficiency in mouse models for intestinal cancer , 2006, Oncogene.

[13]  K. Saito,et al.  Overexpression of stathmin in oral squamous-cell carcinoma: correlation with tumour progression and poor prognosis , 2006, British Journal of Cancer.

[14]  Eytan Domany,et al.  Relationship of gene expression and chromosomal abnormalities in colorectal cancer. , 2006, Cancer research.

[15]  R. Steele,et al.  Chromosomal changes in colorectal adenomas: Relationship to gene mutations and potential for clinical utility , 2006, Genes, chromosomes & cancer.

[16]  R. Lothe,et al.  The order of genetic events associated with colorectal cancer progression inferred from meta‐analysis of copy number changes , 2006, Genes, chromosomes & cancer.

[17]  J Han JM van Krieken,et al.  Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles , 2005, BMC Genomics.

[18]  T. Golub,et al.  Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma , 2005, Nature.

[19]  R. Simon,et al.  Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[20]  L. Ellis,et al.  Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  O. Cummings,et al.  Coming To Terms With Pathologists Over Colon Polyps With Cancer or High-grade Dysplasia , 2005, Journal of clinical gastroenterology.

[22]  I. Frayling,et al.  Systematic review of genetic influences on the prognosis of colorectal cancer , 2004, The British journal of surgery.

[23]  D. Wilkinson,et al.  Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly. , 2004, Developmental cell.

[24]  G. Atweh,et al.  The role of stathmin in the regulation of the cell cycle , 2004, Journal of cellular biochemistry.

[25]  F. Bertucci,et al.  Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters , 2004, Oncogene.

[26]  M. Kanamori,et al.  Correlation of EPHA2 overexpression with high microvessel count in human primary colorectal cancer , 2004, Cancer science.

[27]  Toshio Kuroki,et al.  Role of Smad4 (DPC4) inactivation in human cancer. , 2003, Biochemical and biophysical research communications.

[28]  J. Massagué,et al.  Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.

[29]  Mattias Höglund,et al.  Dissecting karyotypic patterns in colorectal tumors: two distinct but overlapping pathways in the adenoma-carcinoma transition. , 2002, Cancer research.

[30]  J. Arends,et al.  Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. , 2002, Gastroenterology.

[31]  F. Bertucci,et al.  Distinct and complementary information provided by use of tissue and DNA microarrays in the study of breast tumor markers. , 2002, The American journal of pathology.

[32]  G. Noël,et al.  Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer , 2002 .

[33]  F. Speleman,et al.  Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes , 2002, Genome Biology.

[34]  Keith Wilson,et al.  Silence of chromosomal amplifications in colon cancer. , 2002, Cancer research.

[35]  Rieken,et al.  [Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer]. , 2001, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al].

[36]  Christopher M. Gallo,et al.  TGIF2 Interacts with Histone Deacetylase 1 and Represses Transcription* , 2001, The Journal of Biological Chemistry.

[37]  U. Alon,et al.  Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. , 2001, Cancer research.

[38]  E Soeda,et al.  Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines. , 2000, Biochemical and biophysical research communications.

[39]  U. Alon,et al.  Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[40]  Takeo Iwama,et al.  Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis , 1999, Oncogene.

[41]  J. Yokota,et al.  Mutation analysis of the Smad2 gene in human colon cancers using genomic DNA and intron primers. , 1998, Carcinogenesis.

[42]  Irene L Andrulis,et al.  MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma , 1996, Cell.

[43]  Scott E. Kern,et al.  Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers , 1996, Nature Genetics.

[44]  E. Schröck,et al.  Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors , 1996, Genes, chromosomes & cancer.

[45]  A. Knudson.  Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[46]  Carsten Wiuf,et al.  Frequent occurrence of uniparental disomy in colorectal cancer. , 2007, Carcinogenesis.

[47]  R Fodde,et al.  Expression and genomic profiling of colorectal cancer. , 2007, Biochimica et biophysica acta.

[48]  R. Simon,et al.  Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. , 2006, Cancer research.

[49]  E. Keeffe,et al.  Hematologic side effects of PEG interferon and ribavirin. Management with growth factors. , 2005, Journal of clinical gastroenterology.

[50]  J. Massagué,et al.  Mechanisms of TGF-beta signaling from cell membrane to the nucleus. , 2003, Cell.

[51]  G. Buess,et al.  Technique and results of transanal endoscopic microsurgery in early rectal cancer. , 1992, American journal of surgery.