The engine driving the ship: metabolic steering of cell proliferation and death
暂无分享,去创建一个
[1] D. Green,et al. Mitochondria and cell death: outer membrane permeabilization and beyond , 2010, Nature Reviews Molecular Cell Biology.
[2] A. Levine,et al. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function , 2010, Proceedings of the National Academy of Sciences.
[3] S. Sugano,et al. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species , 2010, Proceedings of the National Academy of Sciences.
[4] W. Freije,et al. Metabolic control of G1–S transition: cyclin E degradation by p53-induced activation of the ubiquitin–proteasome system , 2010, The Journal of cell biology.
[5] L. Obeid,et al. The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis* , 2010, The Journal of Biological Chemistry.
[6] M. Colombini,et al. Ceramide and activated Bax act synergistically to permeabilize the mitochondrial outer membrane , 2010, Apoptosis.
[7] Clifford A. Meyer,et al. Transcriptional role of cyclin D1 in development revealed by a genetic–proteomic screen , 2010, Nature.
[8] C. Deng,et al. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. , 2010, Cancer cell.
[9] L. Nutt,et al. Metabolic Control of Oocyte Apoptosis Mediated by 14-3-3ζ-Regulated Dephosphorylation of Caspase-2 (DOI:10.1016/j.devcel.2009.04.005) , 2010 .
[10] S. Moncada,et al. E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation , 2009, Proceedings of the National Academy of Sciences.
[11] David S. Park,et al. Amyloid-β42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism , 2009, Proceedings of the National Academy of Sciences.
[12] D. Green,et al. Novel roles for GAPDH in cell death and carcinogenesis , 2009, Cell Death and Differentiation.
[13] D. Newmeyer,et al. Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release. , 2009, Molecular biology of the cell.
[14] Dominique A. Glauser,et al. The FoxO/Bcl-6/cyclin D2 pathway mediates metabolic and growth factor stimulation of proliferation in Min6 pancreatic β-cells , 2009, Journal of receptor and signal transduction research.
[15] P. Ongusaha,et al. GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress. , 2009, Molecular cell.
[16] L. Nutt,et al. Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase‐2 , 2009, The EMBO journal.
[17] J. G. Pastorino,et al. Hexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanism , 2009, Cell cycle.
[18] D. Green,et al. Characterization of cytoplasmic caspase-2 activation by induced proximity. , 2009, Molecular cell.
[19] G. Krumschnabel,et al. Caspase-2: killer, savior and safeguard—emerging versatile roles for an ill-defined caspase , 2009, Oncogene.
[20] C. Sardet,et al. The CDK4–pRB–E2F1 pathway controls insulin secretion , 2009, Nature Cell Biology.
[21] S. Moncada,et al. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1 , 2009, Nature Cell Biology.
[22] A. Lane,et al. Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases* , 2009, The Journal of Biological Chemistry.
[23] Justin R. Cross,et al. ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation , 2009, Science.
[24] Pumin Zhang,et al. The function of APC/CCdh1 in cell cycle and beyond , 2009, Cell Division.
[25] J. Rathmell,et al. Glucose Metabolism Attenuates p53 and Puma-dependent Cell Death upon Growth Factor Deprivation* , 2008, Journal of Biological Chemistry.
[26] M. Deshmukh,et al. Glucose Metabolism Inhibits Apoptosis in Neurons and Cancer Cells by Redox Inactivation of Cytochrome c , 2008, Nature Cell Biology.
[27] Tak W. Mak,et al. Cytochrome c: functions beyond respiration , 2008, Nature Reviews Molecular Cell Biology.
[28] Rebecca C Taylor,et al. Apoptosis: controlled demolition at the cellular level , 2008, Nature Reviews Molecular Cell Biology.
[29] N. Danial,et al. BCL-2 Family Proteins: Critical Checkpoints of Apoptotic Cell Death , 2007, Clinical Cancer Research.
[30] A. Degterev,et al. A genome-wide RNAi screen reveals multiple regulators of caspase activation , 2007, The Journal of cell biology.
[31] D. Hardie,et al. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy , 2007, Nature Reviews Molecular Cell Biology.
[32] Pascal Barbry,et al. GAPDH and Autophagy Preserve Survival after Apoptotic Cytochrome c Release in the Absence of Caspase Activation , 2007, Cell.
[33] Lewis C. Cantley,et al. AKT/PKB Signaling: Navigating Downstream , 2007, Cell.
[34] J. Rathmell,et al. Filling a GAP(DH) in Caspase-Independent Cell Death , 2007, Cell.
[35] Bing Li,et al. The Role of Chromatin during Transcription , 2007, Cell.
[36] D. Stacey,et al. Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell , 2006, Cell Division.
[37] Ji Luo,et al. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism , 2006, Nature Reviews Genetics.
[38] Eyal Gottlieb,et al. TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis , 2006, Cell.
[39] Anping Li,et al. Cyclin D1 Determines Mitochondrial Function InVivo , 2006, Molecular and Cellular Biology.
[40] Oksana Gavrilova,et al. p53 Regulates Mitochondrial Respiration , 2006, Science.
[41] R. V. van Lier,et al. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. , 2006, Immunity.
[42] S. Kornbluth,et al. The apoptosome: physiological, developmental, and pathological modes of regulation. , 2006, Developmental cell.
[43] D. Green,et al. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. , 2006, Molecular cell.
[44] James M. Roberts,et al. A New Description of Cellular Quiescence , 2006, PLoS biology.
[45] M. Hall,et al. TOR Signaling in Growth and Metabolism , 2006, Cell.
[46] Utpal Banerjee,et al. Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation in Drosophila. , 2005, Developmental cell.
[47] L. Nutt,et al. Metabolic Regulation of Oocyte Cell Death through the CaMKII-Mediated Phosphorylation of Caspase-2 , 2005, Cell.
[48] T. Kuwana,et al. PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53 , 2005, Science.
[49] D. Schubert. Glucose metabolism and Alzheimer's disease , 2005, Ageing Research Reviews.
[50] Russell G. Jones,et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. , 2005, Molecular cell.
[51] D. Green,et al. Do inducers of apoptosis trigger caspase-independent cell death? , 2005, Nature Reviews Molecular Cell Biology.
[52] David Beach,et al. Glycolytic enzymes can modulate cellular life span. , 2005, Cancer research.
[53] C. Thompson,et al. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. , 2004, Molecular cell.
[54] J. Dice,et al. Mechanisms of chaperone-mediated autophagy. , 2004, The international journal of biochemistry & cell biology.
[55] S. Kumar,et al. The biochemical mechanism of caspase-2 activation , 2004, Cell Death and Differentiation.
[56] D. Green,et al. The Pathophysiology of Mitochondrial Cell Death , 2004, Science.
[57] J. Tschopp,et al. The PIDDosome, a Protein Complex Implicated in Activation of Caspase-2 in Response to Genotoxic Stress , 2004, Science.
[58] J. Auwerx,et al. Impaired pancreatic growth, β cell mass, and β cell function in E2F1 –/– mice , 2004 .
[59] N. Hay,et al. Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases , 2004, Molecular and Cellular Biology.
[60] W. Zwerschke,et al. Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence. , 2003, The Biochemical journal.
[61] P. Hammerman,et al. Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival , 2003, Molecular and Cellular Biology.
[62] S. R. Datta,et al. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis , 2003, Nature.
[63] Bruce A. Hay,et al. The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism , 2003, Current Biology.
[64] Petr Pancoska,et al. p53 has a direct apoptogenic role at the mitochondria. , 2003, Molecular cell.
[65] S. R. Datta,et al. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. , 2002, Developmental cell.
[66] Y. Hannun,et al. De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells , 2002, The Journal of Biological Chemistry.
[67] J. Hoek,et al. Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis* , 2002, The Journal of Biological Chemistry.
[68] Xuejun Jiang,et al. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. , 2002, Molecular cell.
[69] H. Yamaguchi,et al. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change , 2001, Oncogene.
[70] P. Rustin,et al. Increased in vivo apoptosis in cells lacking mitochondrial DNA gene expression , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[71] K. Vousden,et al. PUMA, a novel proapoptotic gene, is induced by p53. , 2001, Molecular cell.
[72] M. V. Vander Heiden,et al. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. , 2000, Molecular cell.
[73] T. Taniguchi,et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. , 2000, Science.
[74] S. Rabacchi,et al. Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid , 2000, The Journal of Neuroscience.
[75] P. Nurse. A Long Twentieth Century of the Cell Cycle and Beyond , 2000, Cell.
[76] D. Nicholson,et al. Caspase structure, proteolytic substrates, and function during apoptotic cell death , 1999, Cell Death and Differentiation.
[77] T. Ito,et al. Ceramide Induces Bcl2 Dephosphorylation via a Mechanism Involving Mitochondrial PP2A* , 1999, The Journal of Biological Chemistry.
[78] Susan S. Taylor,et al. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. , 1999, Molecular cell.
[79] R. Bucala,et al. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[80] D. Seol,et al. A Caspase-9 Variant Missing the Catalytic Site Is an Endogenous Inhibitor of Apoptosis* , 1999, The Journal of Biological Chemistry.
[81] M. Moskowitz,et al. Defects in regulation of apoptosis in caspase-2-deficient mice. , 1998, Genes & development.
[82] S. Srinivasula,et al. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.
[83] L. Peso,et al. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. , 1997, Science.
[84] S. R. Datta,et al. Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery , 1997, Cell.
[85] Xiaodong Wang,et al. Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 , 1997, Cell.
[86] Xiaodong Wang,et al. Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c , 1996, Cell.
[87] C. Sherr,et al. D-type cyclins. , 1995, Trends in biochemical sciences.
[88] D. Thorley-Lawson,et al. A novel form of Epstein-Barr virus latency in normal B cells in vivo , 1995, Cell.
[89] John Calvin Reed,et al. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.
[90] C. Sherr. G1 phase progression: Cycling on cue , 1994, Cell.
[91] D. Newmeyer,et al. Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria , 1994, Cell.
[92] D. Wood,et al. The mitochondrial tricarboxylate transport protein. cDNA cloning, primary structure, and comparison with other mitochondrial transport proteins. , 1993, The Journal of biological chemistry.
[93] John Calvin Reed,et al. Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA , 1993, Nature.
[94] B. Puschendorf,et al. Histone acetylation and histone synthesis in mouse fibroblasts during quiescence and restimulation into S-phase , 1991, Molecular and Cellular Biochemistry.
[95] M. Wikstrom. Proton pump coupled to cytochrome c oxidase in mitochondria , 1977, Nature.
[96] O. Warburg. [Origin of cancer cells]. , 1956, Oncologia.
[97] O. Ilkayeva,et al. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. , 2007, Molecular and cellular biology.
[98] J. Auwerx,et al. Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice. , 2004, The Journal of clinical investigation.
[99] B. Amir-Ahmady,et al. Dietary regulation of expression of glucose-6-phosphate dehydrogenase. , 2001, Annual review of nutrition.
[100] J. Klein. Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids , 2000, Journal of Neural Transmission.
[101] A. Lange,et al. Fructose‐2,6‐bisphosphate and control of carbohydrate metabolism in eukaryotes , 1999, BioFactors.
[102] S. Korsmeyer,et al. Cell Death Critical Control Points , 2004, Cell.