Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria

[1]  Piero Dolara,et al.  Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism. , 2010, The Journal of nutritional biochemistry.

[2]  M. Dell’Agli,et al.  Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-kappaB signaling. , 2010, Journal of agricultural and food chemistry.

[3]  S. Romeo,et al.  Antiplasmodial activity of Punica granatum L. fruit rind. , 2009, Journal of ethnopharmacology.

[4]  H. Osada,et al.  RECK negatively regulates matrix metalloproteinase-9 transcription. , 2009, Cancer research.

[5]  B. Witkowski,et al.  In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment , 2008, Antimicrobial Agents and Chemotherapy.

[6]  K. Fritz-Wolf,et al.  Compounds Structurally Related to Ellagic Acid Show Improved Antiplasmodial Activity , 2008, Antimicrobial Agents and Chemotherapy.

[7]  P. Arese,et al.  Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE , 2008, Malaria Journal.

[8]  M. Suchard,et al.  Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects. , 2008, Journal of medicinal food.

[9]  Julie S. Jurenka.  Therapeutic applications of pomegranate (Punica granatum L.): a review. , 2008, Alternative medicine review : a journal of clinical therapeutic.

[10]  S. Mertens-Talcott,et al.  Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers. , 2006, Journal of agricultural and food chemistry.

[11]  I. Clark,et al.  Human malarial disease: a consequence of inflammatory cytokine release , 2006, Malaria Journal.

[12]  David Heber,et al.  Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours. , 2006, The Journal of nutrition.

[13]  G. Opdenakker,et al.  Matrix metalloproteinases, tissue inhibitors of MMPs and TACE in experimental cerebral malaria , 2006, Laboratory Investigation.

[14]  James Varani,et al.  Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. , 2006, Journal of ethnopharmacology.

[15]  N. Seeram,et al.  Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. , 2006, Journal of agricultural and food chemistry.

[16]  S. Romeo,et al.  A structure-activity study for the inhibition of metalloproteinase-9 activity and gene expression by analogues of gallocatechin-3-gallate , 2005, Cellular and Molecular Life Sciences CMLS.

[17]  P. Arese,et al.  Phagocytosis of Hemozoin Enhances Matrix Metalloproteinase-9 Activity and TNF-α Production in Human Monocytes: Role of Matrix Metalloproteinases in the Pathogenesis of Falciparum Malaria1 , 2005, The Journal of Immunology.

[18]  B. Hafeez,et al.  Punica granatum L. extract inhibits IL-1beta-induced expression of matrix metalloproteinases by inhibiting the activation of MAP kinases and NF-kappaB in human chondrocytes in vitro. , 2005, The Journal of nutrition.

[19]  H. Mukhtar,et al.  Anthocyanin‐ and hydrolyzable tannin‐rich pomegranate fruit extract modulates MAPK and NF‐κB pathways and inhibits skin tumorigenesis in CD‐1 mice , 2005, International journal of cancer.

[20]  M. Olivier,et al.  Hemozoin Induces Macrophage Chemokine Expression through Oxidative Stress-Dependent and -Independent Mechanisms1 , 2005, The Journal of Immunology.

[21]  David Heber,et al.  Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. , 2004, Clinica chimica acta; international journal of clinical chemistry.

[22]  J. Hittner,et al.  Elevated Nitric Oxide Production in Children with Malarial Anemia: Hemozoin-Induced Nitric Oxide Synthase Type 2 Transcripts and Nitric Oxide in Blood Mononuclear Cells , 2004, Infection and Immunity.

[23]  B. Cerdá,et al.  The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy–6H–dibenzopyran–6– one derivatives by the colonic microflora of healthy humans , 2004, European journal of nutrition.

[24]  D. Taramelli,et al.  Synergistic and antagonistic interactions between haemozoin and bacterial endotoxin on human and mouse macrophages. , 2003, Parassitologia.

[25]  D. Radzioch,et al.  Hemozoin Increases IFN-γ-Inducible Macrophage Nitric Oxide Generation Through Extracellular Signal-Regulated Kinase- and NF-κB-Dependent Pathways 1 , 2003, The Journal of Immunology.

[26]  M. Dell’Agli,et al.  Inhibition of metalloproteinase-9 activity and gene expression by polyphenolic compounds isolated from the bark of Tristaniopsis calobuxus (Myrtaceae) , 2003, Cellular and Molecular Life Sciences CMLS.

[27]  S. Selvasubramanian,et al.  Immunomodulatory activity of Punica granatum in rabbits--a preliminary study. , 2001, Journal of ethnopharmacology.

[28]  M. Dell’Agli,et al.  In Vitro Antiplasmodial Activity of Extracts of Tristaniopsis Species and Identification of the Active Constituents: Ellagic Acid and 3,4,5-Trimethoxyphenyl-(6‘-O-galloyl)-O-β-d-glucopyranoside , 2001 .

[29]  A. Newby,et al.  Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κB , 1998, FEBS letters.

[30]  D. Goldberg,et al.  An iron-carboxylate bond links the heme units of malaria pigment. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[31]  F. Denizot,et al.  Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. , 1986, Journal of immunological methods.

[32]  W. Trager,et al.  Human malaria parasites in continuous culture. , 1976, Science.

[33]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[34]  H. Mukhtar,et al.  Pomegranate Fruit Extract Modulates UV-B–mediated Phosphorylation of Mitogen-activated Protein Kinases and Activation of Nuclear Factor Kappa B in Normal Human Epidermal Keratinocytes¶ , 2005, Photochemistry and photobiology.

[35]  D. Mazier,et al.  Tumor necrosis factor alpha in the pathogenesis of cerebral malaria. , 2003, Cellular and molecular life sciences : CMLS.

[36]  D. Mazier,et al.  Tumor necrosis factor a in the pathogenesis of cerebral malaria , 2003 .

[37]  D. Radzioch,et al.  Hemozoin increases IFN-gamma-inducible macrophage nitric oxide generation through extracellular signal-regulated kinase- and NF-kappa B-dependent pathways. , 2003, Journal of immunology.

[38]  M. Dell’Agli,et al.  In vitro antiplasmodial activity of extracts of Tristaniopsis species and identification of the active constituents: ellagic acid and 3,4,5-trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside. , 2001, Journal of natural products.

[39]  C. C. Lin,et al.  Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. , 1999, The American journal of Chinese medicine.