Systems and Trans-System Level Analysis Identi fi es Conserved Iron

Eugen I. Urzica,a David Casero,b,c Hiroaki Yamasaki,a,c Scott I. Hsieh,a Lital N. Adler,a Steven J. Karpowicz,a,1 Crysten E. Blaby-Haas,a Steven G. Clarke,a Joseph A. Loo,a,c,d Matteo Pellegrini,b,c and Sabeeha S. Merchanta,c,2 a Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095 bDepartment of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095 c Institute of Genomics and Proteomics, David Geffen School of Medicine at the University of California, Los Angeles, California 90095 dDepartment of Biological Chemistry, David Geffen School of Medicine at the University of California, Los Angeles, California 90095