Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
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Gerald C. Chu | M. Loda | R. Cardiff | S. Signoretti | J. Ward | A. Borowsky | M. Ittmann | G. Chu | Jiaoti Huang | E. Radaelli | B. Robinson | G. Thomas | B. Simons | Philip L. Martin | R. Sullivan
[1] C. Abate-Shen,et al. Modeling prostate cancer in mice: something old, something new, something premalignant, something metastatic , 2013, Cancer and Metastasis Reviews.
[2] R. Cardiff,et al. B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer. , 2012, Cancer research.
[3] Paul G. Hynes,et al. TMPRSS2- Driven ERG Expression In Vivo Increases Self-Renewal and Maintains Expression in a Castration Resistant Subpopulation , 2012, PloS one.
[4] S. Yeh,et al. Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines , 2012, EMBO molecular medicine.
[5] C. Magi-Galluzzi,et al. Intraductal carcinoma of the prostate. , 2012, Archives of pathology & laboratory medicine.
[6] Gerald C. Chu,et al. Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases , 2012, Cell.
[7] L. Tran,et al. Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. , 2012, Cancer research.
[8] M. Ittmann,et al. Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. , 2012, Cancer cell.
[9] Jeffrey M. Rosen,et al. Activation of Wnt Signaling by Chemically Induced Dimerization of LRP5 Disrupts Cellular Homeostasis , 2012, PloS one.
[10] S. Abdulkadir,et al. A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53 , 2011, Oncogene.
[11] D. Tuveson,et al. SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. , 2011, The Journal of clinical investigation.
[12] Stephen J. Salipante,et al. Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers , 2011, Proceedings of the National Academy of Sciences.
[13] J. McKenney,et al. Conditional Expression of the Androgen Receptor Induces Oncogenic Transformation of the Mouse Prostate* , 2011, The Journal of Biological Chemistry.
[14] R. M. Simpson,et al. Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition. , 2011, The American journal of pathology.
[15] M. Henry,et al. Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle? , 2011, Nature Reviews Urology.
[16] L. Tran,et al. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. , 2011, Cancer cell.
[17] Chris Sander,et al. MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors , 2011, PloS one.
[18] Gerald C. Chu,et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression , 2011, Nature.
[19] R. Matusik,et al. Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model , 2010, Oncogene.
[20] P. Scardino,et al. Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens. , 2011, The American journal of pathology.
[21] Fen Wang. Modeling human prostate cancer in genetically engineered mice. , 2011, Progress in molecular biology and translational science.
[22] M. Poutanen,et al. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice. , 2010, Neoplasia.
[23] Yuzhuo Wang,et al. Development of metastatic and non‐metastatic tumor lines from a patient's prostate cancer specimen—identification of a small subpopulation with metastatic potential in the primary tumor , 2010, The Prostate.
[24] Peter S. Nelson,et al. The Effects of Aging on the Molecular and Cellular Composition of the Prostate Microenvironment , 2010, PloS one.
[25] Jiaoti Huang,et al. Identification of a Cell of Origin for Human Prostate Cancer , 2010, Science.
[26] C. Sander,et al. Integrative genomic profiling of human prostate cancer. , 2010, Cancer cell.
[27] R. Cardiff,et al. Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors. , 2010, Cancer cell.
[28] M. Karin,et al. B-cell-derived lymphotoxin promotes castration-resistant prostate cancer , 2010, Nature.
[29] C. Bieberich,et al. MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells , 2010, PloS one.
[30] P. Russell,et al. Modeling prostate cancer: a perspective on transgenic mouse models , 2010, Cancer and Metastasis Reviews.
[31] J. Cuzick,et al. SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation. , 2010, Cancer research.
[32] S. Hayward,et al. Functional Remodeling of Benign Human Prostatic Tissues In Vivo by Spontaneously Immortalized Progenitor and Intermediate Cells , 2009, Stem cells.
[33] S. Hirschfeld,et al. Guiding the Optimal Translation of New Cancer Treatments From Canine to Human Cancer Patients , 2009, Clinical Cancer Research.
[34] M. Teitell,et al. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells , 2009, Proceedings of the National Academy of Sciences.
[35] D. Wilson. Tissue , 2009, The Lancet.
[36] N. Northrup,et al. Prostate cancer in dogs: comparative and clinical aspects. , 2009, Veterinary journal.
[37] Pier Paolo Pandolfi,et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate , 2009, Nature Genetics.
[38] R. de Wit,et al. Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer , 2008, British Journal of Cancer.
[39] G. V. van Leenders,et al. Histopathological and immunohistochemical characterization of canine prostate cancer , 2008, The Prostate.
[40] P. Nelson,et al. A causal role for ERG in neoplastic transformation of prostate epithelium , 2008, Proceedings of the National Academy of Sciences.
[41] F. Yang,et al. Fibroblast growth factor-2 mediates transforming growth factor-β action in prostate cancer reactive stroma , 2008, Oncogene.
[42] M. Teitell,et al. Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. , 2007, Cancer cell.
[43] Leif E. Peterson,et al. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. , 2007, Cancer cell.
[44] J. Resau,et al. Inactivation of Apc in the mouse prostate causes prostate carcinoma. , 2007, Cancer research.
[45] Michael Ittmann,et al. Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer. , 2006, Cancer research.
[46] M. Ather,et al. Neuroendocrine differentiation in prostate cancer. , 2006, Urology.
[47] I. Mellinghoff,et al. Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[48] P. Nelson,et al. The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. , 2006, Cancer research.
[49] J. Tchinda,et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. , 2006, Science.
[50] R. Cardiff,et al. Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model. , 2005, Cancer research.
[51] Feng Yang,et al. Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis. , 2005, Cancer research.
[52] Jason A. Koutcher,et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis , 2005, Nature.
[53] Yuzhuo Wang,et al. Development and characterization of efficient xenograft models for benign and malignant human prostate tissue , 2005, The Prostate.
[54] M. Ittmann,et al. The role of fibroblast growth factors and their receptors in prostate cancer. , 2004, Endocrine-related cancer.
[55] O. Klezovitch,et al. Hepsin promotes prostate cancer progression and metastasis. , 2004, Cancer cell.
[56] M. Rubin,et al. Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee , 2004, Cancer Research.
[57] M. Ittmann,et al. Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia , 2004, The Prostate.
[58] M. Ittmann,et al. Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. , 2003, Cancer research.
[59] M. Ittmann,et al. Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. , 2003, Cancer research.
[60] P. Scardino,et al. Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[61] Mustafa Ozen,et al. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. , 2003, Cancer research.
[62] Leif E. Peterson,et al. Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. , 2003, Cancer research.
[63] T. Graeber,et al. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. , 2003, Cancer cell.
[64] P. Nelson,et al. Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. , 2003, Cancer cell.
[65] Todd R. Golub,et al. Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: The MPAKT model , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[66] R. Vessella,et al. LuCaP 35: A new model of prostate cancer progression to androgen independence , 2003, The Prostate.
[67] Satoru Takahashi,et al. Age‐dependent histopathological findings in the prostate of probasin/SV40 T antigen transgenic rats: Lack of influence of carcinogen or testosterone treatment , 2003, Cancer science.
[68] Jose J. Galvez,et al. Prostatic intraepithelial neoplasia in genetically engineered mice. , 2002, The American journal of pathology.
[69] G. Ayala,et al. Stromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model. , 2002, Cancer research.
[70] S. Hayward,et al. Malignant transformation in a nontumorigenic human prostatic epithelial cell line. , 2001, Cancer research.
[71] K. Imaida,et al. Experimental prostate carcinogenesis - rodent models. , 2000, Mutation research.
[72] M. Ittmann,et al. Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[73] Carlos Cordon-Cardo,et al. Pten is essential for embryonic development and tumour suppression , 1998, Nature Genetics.
[74] R. Dahiya,et al. Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model. , 1998, Differentiation; research in biological diversity.
[75] R. Maronpot,et al. Spontaneous Lesions in Aging FVB/N Mice , 1996, Toxicologic pathology.