KMT5A-methylated SNIP1 promotes triple-negative breast cancer metastasis by activating YAP signaling

[1]  Y. Osuga,et al.  Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer , 2020, Biomolecules.

[2]  Kevin M. McBride,et al.  Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis , 2020, Cancer Research.

[3]  Jianhua Wu,et al.  Downregulation of histone methyltransferase SET8 inhibits progression of hepatocellular carcinoma , 2020, Scientific Reports.

[4]  A. Jemal,et al.  Cancer statistics, 2020 , 2020, CA: a cancer journal for clinicians.

[5]  Y. Tong,et al.  KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells. , 2020, Cancer letters.

[6]  Yingwen Zhang,et al.  CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity , 2019, Nature Communications.

[7]  Emily J. Girard,et al.  Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. , 2019, Cancer cell.

[8]  Fan Mo,et al.  The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α , 2019, Cell Death & Differentiation.

[9]  Xiao-wei Ding,et al.  Monomethyltransferase SET8 facilitates hepatocellular carcinoma growth by enhancing aerobic glycolysis , 2019, Cell Death & Disease.

[10]  Min Gyu Lee,et al.  SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis , 2018, Nature Cell Biology.

[11]  Y. Xiong,et al.  SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response , 2018, Cell reports.

[12]  Chun Xing Li,et al.  The EZH2- H3K27me3-DNMT1 complex orchestrates epigenetic silencing of the wwc1 gene, a Hippo/YAP pathway upstream effector, in breast cancer epithelial cells. , 2018, Cellular signalling.

[13]  Shihao Zhang,et al.  SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis. , 2018, Cancer cell.

[14]  John M. Lamar,et al.  YAP/TAZ Activation as a Target for Treating Metastatic Cancer , 2018, Cancers.

[15]  L. Magnani,et al.  Extensive and systematic rewiring of histone post-translational modifications in cancer model systems , 2018, Nucleic acids research.

[16]  J. Park,et al.  The Role of Hippo Pathway in Cancer Stem Cell Biology , 2018, Molecules and cells.

[17]  Jeong-Hwan Kim,et al.  Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer , 2018, The Journal of clinical investigation.

[18]  Jie He,et al.  KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase , 2017, Nature.

[19]  C. Peng,et al.  Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation. , 2017, Molecular cell.

[20]  Dan Han,et al.  Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity , 2017, Cell.

[21]  Siyuan Song,et al.  MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells , 2017, EMBO reports.

[22]  J. Visvader,et al.  Dysregulation of histone methyltransferases in breast cancer – Opportunities for new targeted therapies? , 2016, Molecular oncology.

[23]  J. Balko,et al.  Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease , 2016, Nature Reviews Clinical Oncology.

[24]  Jianming Xu,et al.  SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-β Responses* , 2016, The Journal of Biological Chemistry.

[25]  A. Jemal,et al.  Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.

[26]  Jidong Zhu,et al.  Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53 , 2015, Nature Communications.

[27]  Young Chul Kim,et al.  Alternative Wnt Signaling Activates YAP/TAZ , 2015, Cell.

[28]  Xiaobing Shi,et al.  Emerging roles of lysine methylation on non-histone proteins , 2015, Cellular and Molecular Life Sciences.

[29]  Yusuke Nakamura,et al.  Critical roles of non-histone protein lysine methylation in human tumorigenesis , 2015, Nature Reviews Cancer.

[30]  S. Li,et al.  Non-histone protein methylation as a regulator of cellular signalling and function , 2014, Nature Reviews Molecular Cell Biology.

[31]  Liuqing Yang,et al.  lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals , 2014, Cell.

[32]  A. Butte,et al.  SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer , 2014, Nature.

[33]  Kwok-Kin Wong,et al.  A genetic screen identifies an LKB1–MARK signalling axis controlling the Hippo–YAP pathway , 2013, Nature Cell Biology.

[34]  D. Nam,et al.  Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells. , 2013, Cancer cell.

[35]  Stephen T. C. Wong,et al.  Identification of Prognosis-Relevant Subgroups in Patients with Chemoresistant Triple-Negative Breast Cancer , 2013, Clinical Cancer Research.

[36]  A. Feinberg The epigenetic basis of common human disease. , 2013, Transactions of the American Clinical and Climatological Association.

[37]  Peter A. Jones,et al.  Cancer genetics and epigenetics: two sides of the same coin? , 2012, Cancer cell.

[38]  Xiao Han,et al.  SET8 promotes epithelial–mesenchymal transition and confers TWIST dual transcriptional activities , 2012, The EMBO journal.

[39]  S. Bicciato,et al.  The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells , 2011, Cell.

[40]  S. Campaner,et al.  The methyltransferase Set7/9 (Setd7) is dispensable for the p53-mediated DNA damage response in vivo. , 2011, Molecular cell.

[41]  M. Esteller,et al.  Cancer epigenetics reaches mainstream oncology , 2011, Nature Medicine.

[42]  D. Reinberg,et al.  Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. , 2010, Molecular cell.

[43]  D. Pan,et al.  The hippo signaling pathway in development and cancer. , 2010, Developmental cell.

[44]  C. Bracken,et al.  Regulation of cyclin D1 RNA stability by SNIP1. , 2008, Cancer research.

[45]  Or Gozani,et al.  Modulation of p53 function by SET8-mediated methylation at lysine 382. , 2007, Molecular cell.

[46]  C. Bracken,et al.  SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes. , 2006, Molecular cell.

[47]  William Arbuthnot Sir Lane,et al.  The c-MYC Oncoprotein Is a Substrate of the Acetyltransferases hGCN5/PCAF and TIP60 , 2004, Molecular and Cellular Biology.

[48]  T. Owen-Hughes,et al.  The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression , 2004, Oncogene.

[49]  D. Livingston,et al.  MYC recruits the TIP60 histone acetyltransferase complex to chromatin , 2003, EMBO reports.

[50]  Yvonne A. Evrard,et al.  c-Myc Transformation Domain Recruits the Human STAGA Complex and Requires TRRAP and GCN5 Acetylase Activity for Transcription Activation* , 2003, Journal of Biological Chemistry.

[51]  B. Lüscher,et al.  Stimulation of c‐MYC transcriptional activity and acetylation by recruitment of the cofactor CBP , 2003, EMBO reports.

[52]  T. Yeates Structures of SET Domain Proteins Protein Lysine Methyltransferases Make Their Mark , 2002, Cell.

[53]  Hengbin Wang,et al.  Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific Methyltransferase , 2002, Current Biology.

[54]  Stephanie Birkey Reffey,et al.  SNIP1 Inhibits NF-κB Signaling by Competing for Its Binding to the C/H1 Domain of CBP/p300 Transcriptional Co-activators* , 2001, The Journal of Biological Chemistry.

[55]  A. Roberts,et al.  A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction. , 2000, Genes & development.

[56]  M. Cole,et al.  The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc , 2000, Molecular and Cellular Biology.