Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality

[1]  M. Vatn,et al.  Growth and Recurrence of Colorectal Polyps: A Double-Blind 3-Year Intervention with Calcium and Antioxidants , 1998, Digestion.

[2]  A. Kristal,et al.  Dietary supplement use and medical conditions: the VITAL study. , 2003, American journal of preventive medicine.

[3]  S. S. Levinson,et al.  Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E. , 2004, Clinica chimica acta; international journal of clinical chemistry.

[4]  F. Cicuttini,et al.  Supplementary vitamin E does not affect the loss of cartilage volume in knee osteoarthritis: a 2 year double blind randomized placebo controlled study. , 2002, The Journal of rheumatology.

[5]  A. Bendich,et al.  Safety of oral intake of vitamin E. , 1988, The American journal of clinical nutrition.

[6]  P. Dowd,et al.  On the mechanism of the anticlotting action of vitamin E quinone. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[7]  P. Galan,et al.  Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial. MIN. VIT. AOX. geriatric network. , 1999, Archives of internal medicine.

[8]  H. Pasantes‐Morales,et al.  Treatment with Taurine, Diltiazem, and Vitamin E Retards the Progressive Visual Field Reduction in Retinitis Pigmentosa: A 3-Year Follow-Up Study , 2002, Metabolic Brain Disease.

[9]  B. Oken.  Practice parameter: Management of dementia (an evidence-based review) , 2001, Neurology.

[10]  G. Y. Wong,et al.  The Hierarchical Logistic Regression Model for Multilevel Analysis , 1985 .

[11]  P. Ducimetiere,et al.  Effects of Long-Term Daily Low-Dose Supplementation With Antioxidant Vitamins and Minerals on Structure and Function of Large Arteries , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[12]  W. R. Bruce,et al.  A randomized trial of vitamins C and E in the prevention of recurrence of colorectal polyps. , 1988, Cancer research.

[13]  L. Wilhelmsen,et al.  Functional deterioration and selenium‐vitamin E treatment in myotonic dystrophy. A placebo‐controlled study , 1994, Journal of internal medicine.

[14]  T A Colacchio,et al.  A clinical trial of antioxidant vitamins to prevent colorectal adenoma. Polyp Prevention Study Group. , 1994, The New England journal of medicine.

[15]  R. Stocker,et al.  Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein , 1993 .

[16]  F. Granado,et al.  Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study. , 2003, Nutrition.

[17]  H. J. Roberts.  Perspective on vitamin E as therapy. , 1981, JAMA.

[18]  Yuk Fai Cheong,et al.  HLM 6: Hierarchical Linear and Nonlinear Modeling , 2000 .

[19]  G. Lamas,et al.  Randomized Trials of Vitamin E in the Treatment and Prevention of Cardiovascular Disease , 2004 .

[20]  Catherine A McCarty,et al.  Vitamin E supplementation and cataract: randomized controlled trial. , 2004, Ophthalmology.

[21]  L. Balluz,et al.  Vitamin and mineral supplement use in the United States. Results from the third National Health and Nutrition Examination Survey. , 2000, Archives of family medicine.

[22]  H. Wollersheim,et al.  Effect of glutathione S-transferase M1 genotype on progression of atherosclerosis in lifelong male smokers. , 2001, Atherosclerosis.

[23]  E. Goetghebeur,et al.  Detection and Estimation of J-shaped Risk-Response Relationships , 1995 .

[24]  P. Albert,et al.  Models for longitudinal data: a generalized estimating equation approach. , 1988, Biometrics.

[25]  C. S. Yang,et al.  An intervention trial to inhibit the progression of precancerous gastric lesions: compliance, serum micronutrients and S‐allyl cysteine levels, and toxicity , 2001, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[26]  P. Shekelle,et al.  Effect of supplemental vitamin E for the prevention and treatment of cardiovascular disease , 2004, Journal of General Internal Medicine.

[27]  P. Lavori,et al.  Vitamin E treatment of tardive dyskinesia. , 1993, The American journal of psychiatry.

[28]  M. Steiner,et al.  Vitamin E plus aspirin compared with aspirin alone in patients with transient ischemic attacks. , 1995, The American journal of clinical nutrition.

[29]  M. Gail,et al.  Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. , 1993, Journal of the National Cancer Institute.

[30]  M. Roncaglioni.  Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general Practice , 2001, The Lancet.

[31]  C. Evelo,et al.  Inhibition of various glutathione S-transferase isoenzymes by RRR-α-tocopherol , 2003 .

[32]  S. Greenland.  Dose‐Response and Trend Analysis in Epidemiology: Alternatives to Categorical Analysis , 1995, Epidemiology.

[33]  P. Taylor,et al.  Nutrition intervention trials in Linxian, China: multiple vitamin/mineral supplementation, cancer incidence, and disease-specific mortality among adults with esophageal dysplasia. , 1993, Journal of the National Cancer Institute.

[34]  E. Topol,et al.  Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials , 2003, The Lancet.

[35]  M. Boaz,et al.  Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial , 2000, The Lancet.

[36]  D. Reid,et al.  A double-blind trial of vitamin E in angina pectoris , 1974 .

[37]  F. Kelly,et al.  Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) , 1996, The Lancet.

[38]  Anthony S. Bryk,et al.  Hierarchical Linear Models: Applications and Data Analysis Methods , 1992 .

[39]  S. Richer.  Multicenter ophthalmic and nutritional age-related macular degeneration study--part 2: antioxidant intervention and conclusions. , 1996, Journal of the American Optometric Association.

[40]  D. Forman,et al.  Vitamins to prevent cancer: supplementary problems , 2004, The Lancet.

[41]  C. Morris,et al.  Routine Vitamin Supplementation To Prevent Cardiovascular Disease: A Summary of the Evidence for the U.S. Preventive Services Task Force , 2003, Annals of Internal Medicine.

[42]  J. Cleary,et al.  Prevention of Tocopherol-mediated Peroxidation in Ubiquinol-10-free Human Low Density Lipoprotein (*) , 1995, The Journal of Biological Chemistry.

[43]  C. Gluud,et al.  Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis , 2004, The Lancet.

[44]  P Woodbury,et al.  A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. , 1997, The New England journal of medicine.

[45]  D. Tribble.  Antioxidant Consumption and Risk of Coronary Heart Disease: Emphasis on Vitamin C, Vitamin E, and β-Carotene A Statement for Healthcare Professionals From the American Heart Association , 1999 .

[46]  J. Manson,et al.  Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality. , 2002, Archives of internal medicine.

[47]  J. Hsia,et al.  Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: A randomized controlled trial , 2002 .

[48]  S. Yusuf,et al.  Vitamin E supplementation and cardiovascular events in high-risk patients. , 2000, The New England journal of medicine.

[49]  E. Guallar,et al.  Use of two-segmented logistic regression to estimate change-points in epidemiologic studies. , 1998, American journal of epidemiology.

[50]  M. Lesser,et al.  Effect of wheat fiber and vitamins C and E on rectal polyps in patients with familial adenomatous polyposis. , 1989, Journal of the National Cancer Institute.

[51]  Bernard Rosner,et al.  A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. , 1993 .

[52]  M. McKenna,et al.  Expressing dietary values for fat-soluble vitamins: changes in concepts and terminology. , 1981, The American journal of clinical nutrition.

[53]  E. Schouten,et al.  Effect of daily vitamin E and multivitamin-mineral supplementation on acute respiratory tract infections in elderly persons: a randomized controlled trial. , 2002, JAMA.

[54]  A. Favier,et al.  A double-blind, placebo-controlled randomized clinical trial of α-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis , 2001 .

[55]  L. Roncucci,et al.  Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas , 1993, Diseases of the colon and rectum.

[56]  L. Appel,et al.  Supplementation of Diets with α-Tocopherol Reduces Serum Concentrations of γ- and δ-Tocopherol in Humans , 2003 .

[57]  N. Brown,et al.  The Roche European American Cataract Trial (REACT): A randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract , 2002, Ophthalmic epidemiology.

[58]  A. Coats.  MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial , 2002 .

[59]  Nea Malila,et al.  Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up. , 2003, JAMA.