MUTAGEN: Multi-User Tool for Annotating GENomes

SUMMARY MUTAGEN is a free prokaryotic annotation system. It offers the advantages of genome comparison, graphical sequence browsers, search facilities and open-source for user-specific adjustments. The web-interface allows several users to access the system from standard desktop computers. The Sulfolobus acidocaldarius genome, and several plasmids and viruses have so far been analysed and annotated using MUTAGEN. AVAILABILITY MUTAGEN is released as open-source software under GPL. The code is available for download and/or contribution at http://dac.molbio.ku.dk/bioinformatics/MUTAGEN/

[1]  T Gaasterland,et al.  MAGPIE: automated genome interpretation. , 1996, Trends in genetics : TIG.

[2]  M. D. Wilkinson,et al.  Genquire: genome annotation browser/editor , 2002, Bioinform..

[3]  Y. Kawarabayasi,et al.  Complete genome sequence of an aerobic thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain7. , 2001, DNA research : an international journal for rapid publication of reports on genes and genomes.

[4]  D. Higgins,et al.  T-Coffee: A novel method for fast and accurate multiple sequence alignment. , 2000, Journal of molecular biology.

[5]  Natalia Ivanova,et al.  The ERGOTM genome analysis and discovery system , 2003, Nucleic Acids Res..

[6]  Kim Rutherford,et al.  Artemis: sequence visualization and annotation , 2000, Bioinform..

[7]  R. Giegerich,et al.  GenDB--an open source genome annotation system for prokaryote genomes. , 2003, Nucleic acids research.

[8]  Mark A. Ragan,et al.  The complete genome of the crenarchaeon Sulfolobus solfataricus P2 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[9]  S. Brenner Errors in genome annotation. , 1999, Trends in genetics : TIG.