Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading.

[1]  H. Sievänen Immobilization and bone structure in humans. , 2010, Archives of biochemistry and biophysics.

[2]  S. Yakar,et al.  IGF-1 and Bone: New Discoveries From Mouse Models , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[3]  Christopher R Jacobs,et al.  Osteocyte mechanobiology and pericellular mechanics. , 2010, Annual review of biomedical engineering.

[4]  Ralph Müller,et al.  Guidelines for assessment of bone microstructure in rodents using micro–computed tomography , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[5]  D Felsenberg,et al.  Recovery of muscle atrophy and bone loss from 90 days bed rest: results from a one-year follow-up. , 2009, Bone.

[6]  G. Mazziotti,et al.  Growth hormone, insulin-like growth factors, and the skeleton. , 2008, Endocrine reviews.

[7]  S. Majumdar,et al.  IGF‐I Receptor Is Required for the Anabolic Actions of Parathyroid Hormone on Bone , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[8]  S. Majumdar,et al.  Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading. , 2007, Journal of applied physiology.

[9]  S. Doty,et al.  Insulin-like growth factor-I is essential for embryonic bone development. , 2006, Endocrinology.

[10]  T. Lang,et al.  Adaptation of the Proximal Femur to Skeletal Reloading After Long‐Duration Spaceflight , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[11]  Alexander G Robling,et al.  Biomechanical and molecular regulation of bone remodeling. , 2006, Annual review of biomedical engineering.

[12]  M. Allen,et al.  Differential bone and muscle recovery following hindlimb unloading in skeletally mature male rats. , 2006, Journal of musculoskeletal & neuronal interactions.

[13]  H. Genant,et al.  Cortical and Trabecular Bone Mineral Loss From the Spine and Hip in Long‐Duration Spaceflight , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[14]  D. Ginzinger,et al.  Skeletal unloading induces resistance to insulin-like growth factor I on bone formation. , 2003, Bone.

[15]  D. Bikle,et al.  The impact of skeletal unloading on bone formation. , 2003, Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology.

[16]  M. Bouxsein,et al.  Osteoblast-specific Knockout of the Insulin-like Growth Factor (IGF) Receptor Gene Reveals an Essential Role of IGF Signaling in Bone Matrix Mineralization* , 2002, The Journal of Biological Chemistry.

[17]  Alexander G Robling,et al.  Improved Bone Structure and Strength After Long‐Term Mechanical Loading Is Greatest if Loading Is Separated Into Short Bouts , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  L. Donahue,et al.  Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. , 2000, Endocrinology.

[19]  S. Xuan,et al.  Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes , 2000, Mammalian Genome.

[20]  C. Bondy,et al.  Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis. , 1995, Endocrinology.

[21]  J. Chow,et al.  Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation. , 1995, The American journal of physiology.

[22]  G. Rodan,et al.  Differential expression of insulin-like growth factor-I (IGF-I) and IGF-II messenger ribonucleic acid in growing rat bone. , 1993, Endocrinology.

[23]  D. Bikle,et al.  Bone response to normal weight bearing after a period of skeletal unloading. , 1989, The American journal of physiology.

[24]  M. Drezner,et al.  Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee , 1987 .

[25]  R. Globus,et al.  Effects of simulated weightlessness on bone mineral metabolism. , 1984, Endocrinology.

[26]  Engin Ozcivici,et al.  Mechanical signals as anabolic agents in bone , 2010, Nature Reviews Rheumatology.

[27]  A. Leblanc,et al.  Skeletal responses to space flight and the bed rest analog: a review. , 2007, Journal of musculoskeletal & neuronal interactions.

[28]  P. Lips,et al.  Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia. , 2007, The Journal of endocrinology.

[29]  Ruth K Globus,et al.  The hindlimb unloading rat model: literature overview, technique update and comparison with space flight data. , 2005, Advances in space biology and medicine.