G1 phase arrest of human smooth muscle cells by heparin, IL-4 and cAMP is linked to repression of cyclin D1 and cdk2.

[1]  P. Vadiveloo,et al.  Differential regulation of cell cycle machinery by various antiproliferative agents is linked to macrophage arrest at distinct G1 checkpoints. , 1996, Oncogene.

[2]  H. Nojima,et al.  Phorbol Ester Inhibits the Phosphorylation of the Retinoblastoma Protein without Suppressing Cyclin D-associated Kinase in Vascular Smooth Muscle Cells (*) , 1996, The Journal of Biological Chemistry.

[3]  L. Hengst,et al.  Translational Control of p27Kip1 Accumulation During the Cell Cycle , 1996, Science.

[4]  J. Jones,et al.  Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. , 1996, Cancer research.

[5]  A. Iavarone,et al.  Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. , 1995, Genes & development.

[6]  M. Roussel,et al.  Rescue of defective mitogenic signaling by D-type cyclins. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[7]  James M. Roberts,et al.  Inhibitors of mammalian G1 cyclin-dependent kinases. , 1995, Genes & development.

[8]  R. Weinberg,et al.  The retinoblastoma protein and cell cycle control , 1995, Cell.

[9]  J. Griffin,et al.  Cdk4 integrates growth stimulatory and inhibitory signals during G1 phase of hematopoietic cells. , 1995, Oncogene.

[10]  D. Reisman,et al.  Transforming growth factor-beta 1 inhibits cyclin D1 expression in intestinal epithelial cells. , 1995, Oncogene.

[11]  James M. Roberts,et al.  lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin , 1994, Nature.

[12]  M. Pierre,et al.  Inhibition of G1 cyclin expression and G1 cyclin-dependent protein kinases by cAMP in an astrocytic cell line. , 1994, Biochemical and biophysical research communications.

[13]  J. Massagué,et al.  Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27 Kip1 ) of cyclin-dependent kinase 4 activation , 1994, Cell.

[14]  L. Alberghina,et al.  Repression of growth-regulated Gl cyclin expression by cyclic AMP in budding yeast , 1994, Nature.

[15]  B. Futcher,et al.  Inhibition of Gl cyclin activity by the Ras/cAMP pathway in yeast , 1994, Nature.

[16]  Gregory J. Hannon,et al.  pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest , 1994, Nature.

[17]  N. L. Thangue,et al.  DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control , 1994 .

[18]  C. Sherr,et al.  Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase , 1994, Molecular and cellular biology.

[19]  E. Harlow,et al.  Identification of G1 kinase activity for cdk6, a novel cyclin D partner , 1994, Molecular and cellular biology.

[20]  S. Shurtleff,et al.  D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.

[21]  G. Evan,et al.  Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues and induces apoptosis. , 1994, Circulation research.

[22]  W. Zhou,et al.  Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery. , 1994, Biochemical and biophysical research communications.

[23]  R. Weinberg,et al.  Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. Shurtleff,et al.  Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. , 1993, Genes & development.

[25]  G. Thibault,et al.  IL-4, but not tumor necrosis factor-alpha, increases endothelial cell adhesiveness for lymphocytes by activating a cAMP-dependent pathway. , 1993, Journal of immunology.

[26]  S. Pang,et al.  Smooth muscle cell proliferation. Expression and kinase activities of p34cdc2 and mitogen-activated protein kinase homologues. , 1993, Circulation research.

[27]  Charles J. Sherr,et al.  Mammalian G1 cyclins , 1993, Cell.

[28]  David M. Livingston,et al.  Functional interactions of the retinoblastoma protein with mammalian D-type cyclins , 1993, Cell.

[29]  M. Pagano,et al.  Cyclin D1 is a nuclear protein required for cell cycle progression in G1. , 1993, Genes & development.

[30]  R Pepperkok,et al.  Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts , 1993, The Journal of cell biology.

[31]  O. Kozawa,et al.  Effect of pituitary adenylate cyclase activating polypeptide on vasopressin-induced proliferation of aortic smooth muscle cells: comparison with vasoactive intestinal polypeptide. , 1993, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[32]  F. C. Lucibello,et al.  Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. , 1993, Journal of cell science.

[33]  M. Hallett,et al.  Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells. , 1992, The Biochemical journal.

[34]  Steven K. Hanks,et al.  Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins , 1992, Cell.

[35]  James M. Roberts,et al.  Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle , 1992 .

[36]  B. Cocks,et al.  Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents. , 1992, The Journal of biological chemistry.

[37]  S. Elledge,et al.  CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[38]  D. Morgan,et al.  Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[39]  F. Hall,et al.  Co-purification of p34cdc2/p58cyclin A proline-directed protein kinase and the retinoblastoma tumor susceptibility gene product: interaction of an oncogenic serine/threonine protein kinase with a tumor-suppressor protein. , 1992, Oncogene.

[40]  K. Matsumoto,et al.  Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[41]  M. Meyerson,et al.  Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase , 1991, Nature.

[42]  S. Elledge,et al.  A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1. , 1991, The EMBO journal.

[43]  M. Auffredou,et al.  IL-4 counteracts anti-mu-induced human B cell proliferation: involvement of a cAMP-dependent inhibitory pathway. , 1991, European cytokine network.

[44]  J. Maller,et al.  Activation of p34cdc2 kinase by cyclin A , 1991, The Journal of cell biology.

[45]  P. Nurse,et al.  The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product , 1990, Cell.

[46]  A. Newby,et al.  Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP. , 1990, Atherosclerosis.

[47]  B. Caleb,et al.  Heparin inhibits c-fos and c-myc mRNA expression in vascular smooth muscle cells. , 1990, Cell regulation.

[48]  Tony Hunter,et al.  Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 , 1989, Cell.

[49]  D. Beach,et al.  The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells , 1989, Cell.

[50]  David Beach,et al.  cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF , 1989, Cell.

[51]  O. Kocher,et al.  Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. , 1988, Atherosclerosis.

[52]  J. Potashkin,et al.  Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2 + and suc1 + , 1987, Cell.

[53]  P. Nurse,et al.  Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2 , 1987, Nature.

[54]  G. Bondjers,et al.  Regional Accumulations of T Cells, Macrophages, and Smooth Muscle Cells in the Human Atherosclerotic Plaque , 1986, Arteriosclerosis.

[55]  R. Ross.  The pathogenesis of atherosclerosis--an update. , 1986, The New England journal of medicine.

[56]  D. Cochran,et al.  Effect of heparin on vascular smooth muscle cells. I. Cell metabolism , 1985, Journal of cellular physiology.

[57]  W. Rutter,et al.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. , 1979, Biochemistry.

[58]  G. Peterson,et al.  A simplification of the protein assay method of Lowry et al. which is more generally applicable. , 1977, Analytical biochemistry.

[59]  A. Clowes,et al.  Suppression by heparin of smooth muscle cell proliferation in injured arteries , 1977, Nature.

[60]  P. Vadiveloo,et al.  Interleukin-4 inhibits human smooth muscle cell proliferation. , 1994, Artery.

[61]  James M. Roberts,et al.  p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. , 1994, Genes & development.

[62]  M. Roussel,et al.  Novel mammalian cyclins (CYL genes) expressed during G1. , 1991, Cold Spring Harbor symposia on quantitative biology.