A bead and spring model for the stiffness of DNA

The chain stiffness of linear native DNA is represented by a generalized bead and spring model recently proposed. It incorporates molecular rigidity by means of springs between beads, which are second neighbors along the contour of the chain. These springs are equivalent to elastic forces having longitudinal and transversal contributions. The model is compared with existing experimental data of sedimentation and low‐angle light scattering to obtain the statistical parameters of DNA. The value of the statistical length obtained with this model is 1300 Å. The same value is obtained with the wormlike chain. Throughout this analysis, excluded volume is left out as a simplifying assumption.

[1]  I. Noda.  Sedimentation coefficient and intrinsic viscosity of semiflexible chains , 1974, Biopolymers.

[2]  H. Yamakawa,et al.  Intrinsic viscosity of wormlike chains. Determination of the shift factor. , 1974, Macromolecules.

[3]  M. Kumbar.  Hydrodynamic properties of ring macromolecules with increasing chain stiffness and excluded volume , 1973 .

[4]  H. Yamakawa,et al.  Translational Friction Coefficient of Wormlike Chains , 1973 .

[5]  M. Kumbar.  Hydrodynamic properties of supercoiled linear polymer molecules , 1973 .

[6]  J. Kovac,et al.  Polymer conformational statistics. III. Modified Gaussian models of stiff chains , 1973 .

[7]  C. Schmid,et al.  Statistical length of DNA from light scattering , 1971, Biopolymers.

[8]  A. I. Krasna,et al.  Characterization of acid‐denatured DNA by low‐angle light scattering , 1970, Biopolymers.

[9]  E. M. Simon.  Dynamic Model for Locally Stiff Ring and Straight Chain Polymers , 1970 .

[10]  M. Fixman,et al.  Polymer conformation and dynamics in solution. , 1970, Annual review of physical chemistry.

[11]  S. Imai.  Hydrodynamical Properties of Stiff Linear and Ring Polymers , 1969 .

[12]  Milton Kerker,et al.  The Scattering of Light and Other Electromagnetic Radiation ~Academic , 1969 .

[13]  B. Zimm,et al.  Molecular weight of T7 and calf thymus DNA by low‐angle light scattering , 1968, Biopolymers.

[14]  J. Hearst,et al.  Sedimentation Coefficients of Linear and Cyclic Wormlike Coils with Excluded‐Volume Effects , 1967 .

[15]  J. Hearst,et al.  On Polymer Dynamics , 1966 .

[16]  J. Hearst,et al.  Sedimentation Constants of Broken Chains and Wormlike Coils , 1962 .

[17]  T. Onishi,et al.  Relaxation Spectrum of Chain High Polymeric Substances , 1958 .