Effects of preoperative methoxamine on blood loss and haemodynamic variables during transurethral prostatic resection under spinal anaesthesia.

Thirty-six patients who presented for transurethral prostatic resection were allocated randomly to one of two groups. Patients in group A were given methoxamine 10 mg i.m., 15 min before spinal anaesthesia. Patients in group B acted as a control group. All patients received spinal anaesthesia. Preoperative administration of methoxamine 10 mg i.m. decreased blood loss significantly and improved haemodynamic stability compared with the control group.

[1]  K. Channer,et al.  Changes in Haemodynamic Variables during Transurethral Resection of the Prostate: Comparison of General and Spinal Anaesthesia , 1994 .

[2]  J. Wildsmith,et al.  Prevention and treatment of hypotension during central neural block. , 1993, British journal of anaesthesia.

[3]  W. Staub,et al.  Phenoxybenzamine in benign prostatic obstruction. , 1988, JAMA.

[4]  J. Kumazawa,et al.  Pharmacological characteristics of smooth muscle in benign prostatic hyperplasia and normal prostatic tissue. , 1987, The Journal of urology.

[5]  H. Lepor,et al.  Alpha 2 adrenergic receptors in canine prostate: biochemical and functional correlations. , 1987, The Journal of urology.

[6]  P. Abrams,et al.  Blood loss during transurethral resection of the prostate , 1982, Anaesthesia.

[7]  S. McGowan,et al.  Anaesthesia for transurethral prostatectomy , 1980, Anaesthesia.

[8]  S. Raz,et al.  Adrenergic and cholinergic receptors in the human prostate, prostatic capsule and bladder neck. , 1975, British journal of urology.

[9]  J. Desmond.  Complications of transurethral prostatic surgery , 1971, Canadian Anaesthetists' Society journal.

[10]  A. Zorgniotti,et al.  Anesthesia, Hemorrhage and Prostatectomy , 1970 .

[11]  J. Desmond,et al.  Bleeding during transurethral prostatic surgery , 1969, Canadian Anaesthetists' Society journal.

[12]  H. Lepor,et al.  The relative efficacy of terazosin versus terazosin and flutamide for the treatment of symptomatic BPH , 1992, The Prostate.

[13]  K. Andersson,et al.  Effects of prazosin and carbachol in patients with benign prostatic obstruction. , 1988, Scandinavian journal of urology and nephrology.

[14]  O. Berséus,et al.  A simple photometric method for determination of blood loss during transurethral surgery. , 1978, Scandinavian journal of urology and nephrology.

[15]  S. Raz,et al.  Pharmacological receptors in the prostate. , 1973, British journal of urology.

[16]  R. Dripps,et al.  The use of methoxamine for maintenance of the circulation during spinal anesthesia. , 1950, Surgery, gynecology & obstetrics.