Assessment of functional outcome in patients of Hirschprung’s disease following two stages Duhamel pull through

Purpose: The aim of this study was to assess the functional outcome in patients of Hirschprung’s disease (HD) following two stages Duhamel pull through operation, that is levelling colostomy followed by the pull through. Materials and Methods: The study was conducted in the Department of Pediatric Surgery of a busy tertiary care children’s hospital. Patients who completed the two stage Duhamel pull through operation at least 6 months prior and aged more than three years were included in the study. The quality of life (QOL) was assessed by using a questionnaire to the parents and clinical examination of the child. Continence status was assessed by applying the Krickenbeck Score. Results: Thirty patients were assessed after completion of two stage Duhamel pull through operation. Quality of life (QOL) was good in 27 patients (90%), fair in 2 patients (6.6%) and poor in 1 patient (3.3%). Voluntary Bowel Movement was present in 25 patients (83.3%) and absent in 5 patients (16.6%). Soiling was absent in 27 patients (90%) and present in 3 patients (10%). Among these 3 patients, 2 patients had grade 1 and 1 patient had grade 2 soiling. Constipation was absent in 26 patients (86.6%) and present in 4 patients (13.3%). Among these 4 patients, 1 patient had grade1 and 3 patients had grade 2 constipation. Conclusion: In patients of Hirschprung’s disease, fecal continence and the quality of life was satisfactory after the two stage Duhamel pull through operation.

[1]  J. Seo [Intestinal neuronal dysplasia]. , 2007, The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi.

[2]  S. Moore,et al.  Preliminary report on the International Conference for the Development of Standards for the Treatment of Anorectal Malformations. , 2005, Journal of pediatric surgery.

[3]  D. Lloyd,et al.  Comparison of functional outcomes of Duhamel and transanal endorectal coloanal anastomosis for Hirschsprung's disease. , 2004, Journal of pediatric surgery.

[4]  I. Vinograd,et al.  Congenital megacolon associated with familial dysautonomia , 1984, European Journal of Pediatrics.

[5]  A. Hadidi Transanal endorectal pull-through for Hirschsprung's disease: experience with 68 patients. , 2003, Journal of pediatric surgery.

[6]  G. Mavridis,et al.  Currarino triad associated with Hirschsprung's disease. , 2003, Journal of pediatric surgery.

[7]  M. Heikkinen,et al.  Long-term anal sphincter performance after surgery for Hirschsprung's disease. , 1997, Journal of pediatric surgery.

[8]  D. Bourdelat,et al.  Duhamel Operation 40 Years After: A Multicentric Study , 1997, European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

[9]  Quality of life and clinical trials , 1995, The Lancet.

[10]  M. Levitt,et al.  Anorectal malformations , 1995, Seminars in pediatric surgery.

[11]  A. Chakravarti,et al.  A genetic study of Hirschsprung disease. , 1990, American journal of human genetics.

[12]  J. Templeton,et al.  Short-term v long-term quality of life in children following repair of high imperforate anus. , 1987, Journal of pediatric surgery.

[13]  P. Baird,et al.  Hirschsprung disease in a large birth cohort. , 1985, Teratology.

[14]  J. Orr,et al.  Presentation and incidence of Hirschsprung's disease. , 1983, British medical journal.

[15]  M. Cloup,et al.  [Intestinal obstruction in the new born]. , 1977, Annales de pediatrie.

[16]  J. Kelly,et al.  The clinical and radiological assessment of anal continence in childhood. , 1972, The Australian and New Zealand journal of surgery.