论文信息 - Optimization of Sustained‐release Diltiazem Formulations in Man by use of an In‐vitro/In‐vivo Correlation

Optimization of Sustained‐release Diltiazem Formulations in Man by use of an In‐vitro/In‐vivo Correlation

In‐vitro/in‐vivo correlations (IVIVC) are useful for predicting in‐vivo results from in‐vitro data. An IVIVC has been used to optimize a hydrocolloidal‐based matrix tablet designed to be bioequivalent to an existing once‐daily diltiazem HCl*** product (Dilacor XR 240 mg; Rhone‐Poulenc Rorer).

K. Yu | D. Friend | M. Gebert | D. Wong | S. A. Altaf

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