Laryngeal Chondroma: A Benign Process with Long-Term Clinical Implications

Chondroma of the laryngeal cartilage is a rare, benign neoplasm which can manifest as a neck mass or, if situated within the airway, as slowly progressive obstruction, hoarseness or dyspnea. The most common location for chondroma is the posterior lamina of the cricoid cartilage; the next most common locations are the thyroid, arytenoid and epiglottic cartilages. Chondroma and low-grade chondrosarcoma are difficult to distinguish from one another histologically. Although chondrosarcoma reportedly recurs, local surgical excision without radical margins and with long-term clinical follow-up is recommended. We report one case of thyroid cartilage chondroma and include a review of radiologic studies and histopathologic analysis results. We also report a second case with severe airway obstruction caused by a large cricoid chondroma. A review of the English language biomedical literature on laryngeal chondroma is included.

[1]  M. Mafee,et al.  Chondrosarcoma of the larynx. Diagnosis with magnetic resonance imaging and computed tomography. , 1990, Archives of otolaryngology--head & neck surgery.

[2]  C. Stayboldt,et al.  Chondrosarcoma of the epiglottis with regional and distant metastasis , 1989, The Laryngoscope.

[3]  C. Norris,et al.  Cartilaginous Tumors of the Trachea and Larynx , 1989, The Annals of otology, rhinology, and laryngology.

[4]  J. Batsakis,et al.  Cartilage Tumors of the Larynx , 1988, Southern medical journal.

[5]  G. Snow,et al.  Cartilagenous tumours of the larynx , 1987, The Journal of Laryngology & Otology.

[6]  D. Brown,et al.  Laryngeal chondrosarcoma: gross pathological, histologic and electron microscopic characteristics. , 1985, Canadian journal of surgery. Journal canadien de chirurgie.

[7]  H. Tucker,et al.  Chondrosarcoma of the Larynx , 1984, The Annals of otology, rhinology, and laryngology.

[8]  K. Unni,et al.  Cartilaginous Tumors of the Larynx: A Series of 33 Patients , 1982, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[9]  H. Tucker,et al.  Chondroma of the larynx. Surgical technique. , 1981, Archives of otolaryngology.

[10]  J. Singh,et al.  Cartilagenous tumors of the larynx: A review of literature and two case experiences , 1980, The Laryngoscope.

[11]  R. Cantrell,et al.  Conservative Surgical Treatment of Chondrosarcoma of the Larynx , 1980, The Annals of otology, rhinology, and laryngology.

[12]  J. S. Lewis,et al.  Radiologic diagnosis of chondroma and chondrosarcoma of the larynx. , 1975, Archives of otolaryngology.

[13]  H. Biller,et al.  Cartilaginous tumors of the larynx. , 1974, Archives of otolaryngology.

[14]  H. M. Jones Cartilaginous tumours of the head and neck , 1973, The Journal of Laryngology & Otology.

[15]  K. Balogh,et al.  Cartilaginous tumors of the larynx A clinicopathologic study of 10 new cases and a review of the literature , 1970, Cancer.

[16]  V. Hyams,et al.  Cartilaginous tumors of the larynx , 1970, The Laryngoscope.

[17]  C. Wengraf Second Primary Laryngeal Chondroma , 1969, The Journal of Laryngology & Otology.

[18]  L. Barsocchini,et al.  Cartilaginous tumours of the larynx. A review of the literature and a report of four cases. , 1968, The Annals of otology, rhinology, and laryngology.

[19]  A. Rao A Case of Chondroma of the Epiglottis , 1964, The Journal of Laryngology & Otology.

[20]  E. Huizinga,et al.  IV Bronchography in Agenesia and Hypoplasia of the Lung , 1964, The Annals of otology, rhinology, and laryngology.

[21]  E. W. Cocke Benign cartilaginous tumors of the larynx , 1962, The Laryngoscope.

[22]  J. F. Hora,et al.  Laryngeal chondroma. , 1961, A M A Archives of Otolaryngology.

[23]  W. Walter Chondroma of the larynx. Report of a case and a review of the literature. , 1959, The Annals of otology, rhinology, and laryngology.

[24]  M. Schiff,et al.  Chondroma of the larynx; report of a case with recurrence after twenty-eight years. , 1959, A.M.A. archives of otolaryngology.

[25]  E. Thompson Cancer of the larynx. , 1957, Journal of the National Medical Association.

[26]  M. G. Baradulina [Chondroma of the larynx]. , 1956, Vestnik otorinolaringologii.

[27]  H. Sirota,et al.  Chondrosarcoma of the larynx. , 1952, A.M.A. archives of otolaryngology.

[28]  M. Link Chondroma and chondrosarcoma of the larynx. , 1949, The Annals of otology, rhinology, and laryngology.

[29]  S. Dupertuis,et al.  Chondroma of the Larynx. Review of the literature and report of two cases , 1944 .

[30]  H. Jaffe,et al.  Chondrosarcoma of Bone. , 1943, The American journal of pathology.

[31]  E. Gatewood CHONDROMA OF THE LARYNX: REPORT OF TWO CASES IN WHICH LARYNGOFISSURE WAS EMPLOYED , 1942 .

[32]  H. B. Orton L Chondroma of the Larynx , 1941 .

[33]  F. Neuffer,et al.  CHONDROMA OF THE LARYNX REQUIRING TOTAL LARYNGECTOMY , 1940 .

[34]  C. Jackson The Larynx and Its Diseases , 1937, The Indian Medical Gazette.

[35]  H. B. Graham XXII. Chondroma of the Larynx: Case Report , 1934 .

[36]  F. A. Figi XXVIII. Chondroma of the Larynx: Report of Six Cases , 1932 .

[37]  D. Neilson Chondroma of the Thyroid Cartilage , 1929, The Journal of Laryngology & Otology.

[38]  H S Birkett,et al.  CHRONDROMA OF THE LARYNX. , 1927, Canadian Medical Association journal.

[39]  Irwin Morre Cartilaginous Tumours of the Larynx , 1925, The Journal of Laryngology & Otology.

[40]  B. Gordon Cartilaginous tumors of the larynx. , 1918 .