Fluid preload before spinal anaesthesia in Caesarean section: the effect on neonatal acid–base status

Background and objective: We evaluated the effect of two different preload solutions: (i) Ringer's lactate (compound sodium lactate intravenous infusion BP) and (ii) 0.9% sodium chloride solution on the neonatal acid–base status of the newborn infants. The two standard regimens were compared to detect a possible difference. Methods: A 2 L crystalloid fluid bolus was administered immediately before spinal anaesthesia for elective Caesarean section in two groups of 20 healthy parturients, while rigorously maintaining maternal normotension. Results: No significant differences in the Apgar scores at 1 and 5 min, or infant well‐being were demonstrated in either of the two groups. The data show that umbilical artery PCO2 is lower in the Ringer's lactate group and that pH is insignificantly higher by 0.03. Conclusions: The choice of Ringer's lactate or saline for fluid preload does not have any effect on neonatal well‐being.

[1]  S. Halpern,et al.  The Effects of an Increase of Central Blood Volume Before Spinal Anesthesia for Cesarean Delivery: A Qualitative Systematic Review , 2001, Anesthesia and analgesia.

[2]  C. Rout,et al.  Spinal hypotension associated with Cesarean section: will preload ever work? , 1999, Anesthesiology.

[3]  T. Mashimo,et al.  Effects of crystalloid and colloid preload on blood volume in the parturient undergoing spinal anesthesia for elective Cesarean section. , 1999, Anesthesiology.

[4]  M. Vercauteren,et al.  Hydroxyethylstarch compared with modified gelatin as volume preload before spinal anaesthesia for Caesarean section. , 1996, British journal of anaesthesia.

[5]  A. Rubenstein,et al.  Prevention of Hypotension After Spinal Anesthesia for Cesarean Section: Six Percent Hetastarch Versus Lactated Ringer's Solution , 1995, Anesthesia and analgesia.

[6]  J. Wildsmith,et al.  Prevention and treatment of hypotension during central neural block. , 1993, British journal of anaesthesia.

[7]  C. Rout,et al.  Leg elevation and wrapping in the prevention of hypotension following spinal anaesthesia for elective Caesarean section , 1993, Anaesthesia.

[8]  B. Leighton,et al.  INFLUENCE OF THE CHOICE OF CRYSTALLOID SOLUTION ON NEONATAL ACID-BASE STATUS AT CESAREAN SECTION , 1987 .

[9]  D. I. Edelstone,et al.  Fetal Acid—Base State Following Spinal or Epidural Anesthesia for Cesarean Section , 1980, Obstetrics and gynecology.

[10]  D. Thompson,et al.  Prevention of spinal hypotension associated with Cesarean section. , 1976, Anesthesiology.

[11]  M. Burton,et al.  Time and lateral tilt at Caesarean section. , 1972, British journal of anaesthesia.

[12]  E. Cosmi,et al.  Biochemical Status and Clinical Condition of Mother and Infant at Cesarean Section , 1969, Anesthesia and analgesia.

[13]  S. Datta,et al.  Method of ephedrine administration and nausea and hypotension during spinal anesthesia for cesarean section. , 1982, Anesthesiology.

[14]  W. Marais [Elective caesarean section]. , 1979, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.